World's Best Scientists 2026 revealed!
George J. Giudice

George J. Giudice

D-Index & Metrics

Biology and Biochemistry

D-Index
55
Citations
10103
World Ranking
15139
National Ranking
6330

Overview

George J. Giudice is affiliated with the University of Iowa in the United States and works primarily within the field of Medicine. Their research spans various subfields including Pathology and Forensic Medicine, Genetics, Rheumatology, and Cell Biology.

The research topics covered by George J. Giudice include:

  • Autoimmune Bullous Skin Diseases
  • Coagulation, Bradykinin, Polyphosphates, and Angioedema
  • Urticaria and Related Conditions
  • Skin and Cellular Biology Research

Among their recent publications, two papers were published in 2020 through UNC Libraries:

  • Subepidermal blistering induced by human autoantibodies to BP180 requires innate immune players in a humanized bullous pemphigoid mouse model (2020, UNC Libraries)
  • Neutrophil elastase cleaves the murine hemidesmosomal protein BP180/type XVII collagen and generates degradation products that modulate experimental bullous pemphigoid (2020, UNC Libraries)

Frequent collaborators in their research include Zhi Liu, Ning Li, Luis A. Díaz, Wen Sui, and Ming-Lang Zhao. Both Zhi Liu and Ning Li have collaborated twice, as has Luis A. Díaz, while Wen Sui and Ming-Lang Zhao have each collaborated once.

Their work has been published predominantly in UNC Libraries, reflecting a consistent publishing venue in their recent scholarly output.

Best Publications

  • A passive transfer model of the organ-specific autoimmune disease, bullous pemphigoid, using antibodies generated against the hemidesmosomal antigen, BP180.

    Zhi Liu;Luis A. Diaz;James L. Troy;James L. Troy;Ann F. Taylor

  • Cloning and primary structural analysis of the bullous pemphigoid autoantigen BP180.

    George J Giudice;Daryl J Emery;Luis A Diaz

  • Isolation of a human epidermal cDNA corresponding to the 180-kD autoantigen recognized by bullous pemphigoid and herpes gestationis sera. Immunolocalization of this protein to the hemidesmosome.

    L A Diaz;H Ratrie rd;H Ratrie rd;W S Saunders;W S Saunders;S Futamura

  • Bullous pemphigoid and herpes gestationis autoantibodies recognize a common non-collagenous site on the BP180 ectodomain

    G.J. Giudice;D.J. Emery;B.D. Zelickson;G.J. Anhalt

  • Tight Clustering of Extracellular BP180 Epitopes Recognized by Bullous Pemphigoid Autoantibodies

    Detlef Zillikens;Pamela A. Rose;Shawn D. Balding;Zhi Liu

  • The role of complement in experimental bullous pemphigoid.

    Zhi Liu;George J. Giudice;Susan J. Swartz;Janet A. Fairley;Janet A. Fairley

  • Cicatricial Pemphigoid Autoantibodies React with Multiple Sites on the BP180 Extracellular Domain

    Shawn D. Balding;Catherine Prost;Luis A. Diaz;Philippe Bernard

  • A major role for neutrophils in experimental bullous pemphigoid

    Zhi Liu;George J. Giudice;Xiaoye Zhou;Susan J. Swartz

  • 92-kD gelatinase is produced by eosinophils at the site of blister formation in bullous pemphigoid and cleaves the extracellular domain of recombinant 180-kD bullous pemphigoid autoantigen.

    M Ståhle-Bäckdahl;M Inoue;G J Guidice;W C Parks

  • A novel subepidermal blistering disease with autoantibodies to a 200-kDa antigen of the basement membrane zone

    Detlef Zillikens;Detlef Zillikens;Yoshie Kawahara;Akira Ishiko;Hiroshi Shimizu

  • A Highly Sensitive Enzyme-Linked Immunosorbent Assay for the Detection of Circulating Anti-BP180 Autoantibodies in Patients with Bullous Pemphigoid

    Detlef Zillikens;Jose M. Mascaro;Pamela A. Rose;Zhi Liu

  • The Prevalence of Antibodies against Desmoglein 1 in Endemic Pemphigus Foliaceus in Brazil

    Simon J.P. Warren;Mong Shang Lin;George J. Giudice;Raymond G. Hoffmann

  • A pathogenic role for IgE in autoimmunity: bullous pemphigoid IgE reproduces the early phase of lesion development in human skin grafted to nu/nu mice.

    Janet A. Fairley;Christopher T. Burnett;Chang-Ling Fu;David L. Larson

  • A critical role for neutrophil elastase in experimental bullous pemphigoid

    Zhi Liu;Steven D. Shapiro;Xiaoye Zhou;Sally S. Twining

  • Autoantibodies in lichen planus pemphigoides react with a novel epitope within the C-terminal NC16A domain of BP180.

    Detlef Zillikens;Detlef Zillikens;Frederic Caux;Jose M. Mascaro;Ulrich Wesselmann

  • Bullous pemphigoid and cicatricial pemphigoid autoantibodies react with ultrastructurally separable epitopes on the BP180 ectodomain: Evidence that BP180 spans the lamina lucida

    Christophe Bédane;James R. McMillan;Shawn D. Balding;Philippe Bernard

  • The human keratin genes and their differential expression.

    Elaine Fuchs;Angela L. Tyner;George J. Giudice;Douglas Marchuk

  • Autoantibodies to BP180 associated with bullous pemphigoid release interleukin-6 and interleukin-8 from cultured human keratinocytes.

    Enno Schmidt;Stanislaus Reimer;Silke Jainta;Eva-Bettina Bröcker

  • Identification of a potential effector function for IgE autoantibodies in the organ-specific autoimmune disease bullous pemphigoid

    Otobia G. Dimson;George J. Giudice;Chang Ling Fu;Francoise Van den Bergh

  • Identification of two collagen domains within the bullous pemphigoid autoantigen, BP180.

    G J Giudice;H L Squiquera;P M Elias;L A Diaz

Frequent Co-Authors

Luis A. Diaz
Luis A. Diaz Memorial Sloan Kettering Cancer Center
Janet A. Fairley
Janet A. Fairley University of Iowa
Zhi Liu
Zhi Liu University of North Carolina at Chapel Hill
Detlef Zillikens
Detlef Zillikens University of Lübeck
Enno Schmidt
Enno Schmidt University of Lübeck
Leena Bruckner-Tuderman
Leena Bruckner-Tuderman University of Freiburg
M. Peter Marinkovich
M. Peter Marinkovich Stanford University
Grant James Anhalt
Grant James Anhalt Johns Hopkins University
Elaine Fuchs
Elaine Fuchs Rockefeller University
Hiroshi Shimizu
Hiroshi Shimizu Hokkaido University

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