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Alberto Bardelli

Alberto Bardelli

D-Index & Metrics

Medicine

D-Index
122
Citations
82479
World Ranking
3407
National Ranking
98

Research.com Recognitions

  • Member of the European Molecular Biology Organization (EMBO)
  • Member of the European Molecular Biology Organization (EMBO)

Overview

Alberto Bardelli is affiliated with the University of Turin in Italy and has a significant body of research concentrated in medicine, particularly within oncology and molecular biology. Their publication record includes extensive work in cancer genomics, diagnostics, and colorectal cancer treatments, reflecting a focused interest in the genetic factors underlying colorectal cancer and related therapies.

Their research spans various subfields, with a high concentration in oncology, molecular biology, cancer research, pathology and forensic medicine, and pulmonary and respiratory medicine.

Frequent publication venues for Bardelli include Cancer Research, Annals of Oncology, Cancer Discovery, Cancers, and the Journal of Clinical Oncology, illustrating sustained contributions to prominent journals in the oncology and medical research communities.

Key recent publications authored by or involving Bardelli are:

  • EGFR Blockade Reverts Resistance to KRASG12C Inhibition in Colorectal Cancer, 2020, Cancer Discovery
  • High-dose vitamin C enhances cancer immunotherapy, 2020, Science Translational Medicine
  • Precision oncology in metastatic colorectal cancer - from biology to medicine, 2021, Nature Reviews Clinical Oncology
  • Circulating tumor DNA to guide rechallenge with panitumumab in metastatic colorectal cancer: the phase 2 CHRONOS trial, 2022, Nature Medicine
  • The status of tumor mutational burden and immunotherapy, 2022, Nature Cancer

Among frequent co-authors of Bardelli are Salvatore Siena, Federica Di Nicolantonio, Andrea Sartore-Bianchi, Silvia Marsoni, and Giovanni Crisafulli. These collaborators have contributed to a range of research efforts spanning cancer genomics and treatment strategies.

Main topics of Bardelli's work cover:

  • Cancer Genomics and Diagnostics
  • Colorectal Cancer Treatments and Studies
  • Genetic factors in colorectal cancer
  • Cancer Immunotherapy and Biomarkers
  • DNA Repair Mechanisms
  • Lung Cancer Treatments and Mutations
  • Melanoma and MAPK Pathways

Alberto Bardelli is recognized as a member of the European Molecular Biology Organization (EMBO).

Best Publications

  • Detection of Circulating Tumor DNA in Early- and Late-Stage Human Malignancies

    Chetan Bettegowda;Chetan Bettegowda;Mark Sausen;Rebecca J. Leary;Isaac Kinde

  • High frequency of mutations of the PIK3CA gene in human cancers

    Yardena Samuels;Zhenghe Wang;Alberto Bardelli;Natalie Silliman

  • ESMO consensus guidelines for the management of patients with metastatic colorectal cancer

    E. Van Cutsem;A. Cervantes;R. Adam;A. Sobrero

  • Liquid Biopsies: Genotyping Circulating Tumor DNA

    Luis A. Diaz;Alberto Bardelli

  • International network of cancer genome projects

    Thomas J. Hudson;Thomas J. Hudson;Warwick Anderson;Axel Aretz;Anna D. Barker

  • Unresponsiveness of colon cancer to BRAF(V600E) inhibition through feedback activation of EGFR

    Anirudh Prahallad;Chong Sun;Sidong Huang;Federica Di Nicolantonio

  • Wild-Type BRAF Is Required for Response to Panitumumab or Cetuximab in Metastatic Colorectal Cancer

    Federica Di Nicolantonio;Miriam Martini;Francesca Molinari;Andrea Sartore-Bianchi

  • Emergence of KRAS mutations and acquired resistance to anti-EGFR therapy in colorectal cancer

    Sandra Misale;Rona Yaeger;Sebastijan Hobor;Elisa Scala

  • Effects of KRAS, BRAF, NRAS, and PIK3CA mutations on the efficacy of cetuximab plus chemotherapy in chemotherapy-refractory metastatic colorectal cancer: a retrospective consortium analysis

    Wendy De Roock;Bart Claes;David Bernasconi;Jef De Schutter

  • Liquid biopsy: monitoring cancer-genetics in the blood.

    Emily Crowley;Federica Di Nicolantonio;Fotios Loupakis;Alberto Bardelli

  • Integrating liquid biopsies into the management of cancer

    Giulia Siravegna;Silvia Marsoni;Salvatore Siena;Alberto Bardelli

  • Tumorigenesis: RAF/RAS oncogenes and mismatch-repair status.

    Harith Rajagopalan;Alberto Bardelli;Christoph Lengauer;Kenneth W. Kinzler

  • A multifunctional docking site mediates signaling and transformation by the hepatocyte growth factor/scatter factor receptor family

    Carola Ponzetto;Alberto Bardelli;Alberto Bardelli;Zhu Zhen;Flavio Maina

  • Gene copy number for epidermal growth factor receptor (EGFR) and clinical response to antiEGFR treatment in colorectal cancer: a cohort study

    Mauro Moroni;Silvio Veronese;Silvia Benvenuti;Giovanna Marrapese

  • Dual-targeted therapy with trastuzumab and lapatinib in treatment-refractory, KRAS codon 12/13 wild-type, HER2-positive metastatic colorectal cancer (HERACLES): A proof-of-concept, multicentre, open-label, phase 2 trial

    Andrea Sartore-Bianchi;Livio Trusolino;Cosimo Martino;Katia Bencardino

  • Clonal evolution and resistance to EGFR blockade in the blood of colorectal cancer patients

    Giulia Siravegna;Benedetta Mussolin;Michela Buscarino;Giorgio Corti

  • Oncogenic Activation of the RAS/RAF Signaling Pathway Impairs the Response of Metastatic Colorectal Cancers to Anti–Epidermal Growth Factor Receptor Antibody Therapies

    Silvia Benvenuti;Andrea Sartore-Bianchi;Federica Di Nicolantonio;Carlo Zanon

  • A molecularly annotated platform of patient-derived xenografts ("xenopatients") identifies HER2 as an effective therapeutic target in cetuximab-resistant colorectal cancer.

    Andrea Bertotti;Giorgia Migliardi;Francesco Galimi;Francesco Sassi

  • Tumor cells can follow distinct evolutionary paths to become resistant to epidermal growth factor receptor inhibition

    Aaron N. Hata;Matthew J. Niederst;Hannah L. Archibald;Maria Gomez-Caraballo

  • PIK3CA mutations in colorectal cancer are associated with clinical resistance to EGFR-targeted monoclonal antibodies.

    Andrea Sartore-Bianchi;Miriam Martini;Francesca Molinari;Silvio Veronese

Frequent Co-Authors

Salvatore Siena
Salvatore Siena University of Milan
Andrea Sartore-Bianchi
Andrea Sartore-Bianchi University of Milan
Paolo M. Comoglio
Paolo M. Comoglio FIRC Institute of Molecular Oncology
Enzo Medico
Enzo Medico University of Turin
Fortunato Ciardiello
Fortunato Ciardiello University of Campania "Luigi Vanvitelli"
Vittorina Zagonel
Vittorina Zagonel Mario Negri Institute for Pharmacological Research
Sara Lonardi
Sara Lonardi Istituto Oncologico Veneto
Josep Tabernero
Josep Tabernero Vall d´Hebron Institute of Oncology
Filippo de Braud
Filippo de Braud University of Milan
Bert Vogelstein
Bert Vogelstein Johns Hopkins University

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