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84
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Overview

Sara Lonardi is affiliated with the Istituto Oncologico Veneto in Italy. Their research primarily spans the field of Medicine, with significant contributions in Oncology, Pulmonary and Respiratory Medicine, Pathology and Forensic Medicine, Surgery, and Cancer Research.

Their scholarly work addresses a range of main topics, including:

  • Colorectal Cancer Treatments and Studies
  • Genetic factors in colorectal cancer
  • Gastric Cancer Management and Outcomes
  • Cancer Genomics and Diagnostics
  • Cancer Immunotherapy and Biomarkers
  • Hepatocellular Carcinoma Treatment and Prognosis
  • Lung Cancer Treatments and Mutations

Some recent papers featuring contributions linked to their research interest include:

  • The KEYNOTE-811 trial of dual PD-1 and HER2 blockade in HER2-positive gastric cancer, 2021, Nature
  • Pembrolizumab plus trastuzumab and chemotherapy for HER2-positive gastric or gastro-oesophageal junction adenocarcinoma: interim analyses from the phase 3 KEYNOTE-811 randomised placebo-controlled trial, 2023, The Lancet
  • Upfront FOLFOXIRI plus bevacizumab and reintroduction after progression versus mFOLFOX6 plus bevacizumab followed by FOLFIRI plus bevacizumab in the treatment of patients with metastatic colorectal cancer (TRIBE2): a multicentre, open-label, phase 3, randomised, controlled trial, 2020, The Lancet Oncology
  • The Pan-Immune-Inflammation Value is a new prognostic biomarker in metastatic colorectal cancer: results from a pooled-analysis of the Valentino and TRIBE first-line trials, 2020, British Journal of Cancer
  • Neoadjuvant and adjuvant pembrolizumab plus chemotherapy in locally advanced gastric or gastro-oesophageal cancer (KEYNOTE-585): an interim analysis of the multicentre, double-blind, randomised phase 3 study, 2023, The Lancet Oncology

Sara Lonardi frequently collaborates with several authors, including:

  • Filippo Pietrantonio
  • Chiara Cremolini
  • Francesca Bergamo
  • Matteo Fassan
  • Gianluca Masi

Their publications are often found in key journals such as:

  • Journal of Clinical Oncology
  • Annals of Oncology
  • European Journal of Cancer
  • ESMO Open
  • Cancers

Best Publications

  • Nivolumab in patients with metastatic DNA mismatch repair-deficient or microsatellite instability-high colorectal cancer (CheckMate 142): an open-label, multicentre, phase 2 study

    Michael J. Overman;Ray McDermott;Joseph L. Leach;Sara Lonardi

  • Durable clinical benefit with nivolumab plus ipilimumab in DNA mismatch repair-deficient/microsatellite instability-high metastatic colorectal cancer

    Michael J. Overman;Sara Lonardi;Ka Yeung Mark Wong;Heinz Josef Lenz

  • Encorafenib, Binimetinib, and Cetuximab in BRAF V600E–Mutated Colorectal Cancer

    Scott Kopetz;Axel Grothey;Rona Yaeger;Eric Van Cutsem

  • FOLFOXIRI plus bevacizumab versus FOLFIRI plus bevacizumab as first-line treatment of patients with metastatic colorectal cancer: updated overall survival and molecular subgroup analyses of the open-label, phase 3 TRIBE study

    Chiara Cremolini;Fotios Loupakis;Carlotta Antoniotti;Cristiana Lupi

  • Initial Therapy with FOLFOXIRI and Bevacizumab for Metastatic Colorectal Cancer

    Fotios Loupakis;Chiara Cremolini;Gianluca Masi;Sara Lonardi

  • Dual-targeted therapy with trastuzumab and lapatinib in treatment-refractory, KRAS codon 12/13 wild-type, HER2-positive metastatic colorectal cancer (HERACLES): A proof-of-concept, multicentre, open-label, phase 2 trial

    Andrea Sartore-Bianchi;Livio Trusolino;Cosimo Martino;Katia Bencardino

  • Ramucirumab versus placebo in combination with second-line FOLFIRI in patients with metastatic colorectal carcinoma that progressed during or after first-line therapy with bevacizumab, oxaliplatin, and a fluoropyrimidine (RAISE): A randomised, double-blind, multicentre, phase 3 study

    Josep Tabernero;Takayuki Yoshino;Allen Lee Cohn;Radka Obermannova

  • Primary Tumor Response to Preoperative Chemoradiation With or Without Oxaliplatin in Locally Advanced Rectal Cancer: Pathologic Results of the STAR-01 Randomized Phase III Trial

    Carlo Aschele;Luca Cionini;Sara Lonardi;Carmine Pinto

  • Rechallenge for Patients With RAS and BRAF Wild-Type Metastatic Colorectal Cancer With Acquired Resistance to First-line Cetuximab and Irinotecan: A Phase 2 Single-Arm Clinical Trial.

    Chiara Cremolini;Daniele Rossini;Emanuela Dell’Aquila;Sara Lonardi

  • Assessment of a HER2 scoring system for colorectal cancer: results from a validation study

    Emanuele Valtorta;Cosimo Martino;Andrea Sartore-Bianchi;Frédérique Penaullt-Llorca

  • Upfront FOLFOXIRI plus bevacizumab and reintroduction after progression versus mFOLFOX6 plus bevacizumab followed by FOLFIRI plus bevacizumab in the treatment of patients with metastatic colorectal cancer (TRIBE2): a multicentre, open-label, phase 3, randomised, controlled trial

    Chiara Cremolini;Carlotta Antoniotti;Daniele Rossini;Sara Lonardi

  • Ramucirumab with cisplatin and fluoropyrimidine as first-line therapy in patients with metastatic gastric or junctional adenocarcinoma (RAINFALL): a double-blind, randomised, placebo-controlled, phase 3 trial.

    Charles S Fuchs;Kohei Shitara;Maria Di Bartolomeo;Sara Lonardi

  • First-Line Nivolumab Plus Low-Dose Ipilimumab for Microsatellite Instability-High/Mismatch Repair-Deficient Metastatic Colorectal Cancer: The Phase II CheckMate 142 Study.

    Heinz-Josef Lenz;Eric Van Cutsem;Maria Luisa Limon;Ka Yeung Mark Wong

  • FOLFOXIRI plus bevacizumab as first-line treatment in BRAF mutant metastatic colorectal cancer

    F. Loupakis;C. Cremolini;L. Salvatore;G. Masi

  • Gefitinib in patients with progressive high-grade gliomas: a multicentre phase II study by Gruppo Italiano Cooperativo di Neuro-Oncologia (GICNO)

    E Franceschi;G Cavallo;S Lonardi;E Magrini

  • Early tumor shrinkage and depth of response predict long-term outcome in metastatic colorectal cancer patients treated with first-line chemotherapy plus bevacizumab: results from phase III TRIBE trial by the Gruppo Oncologico del Nord Ovest

    Chiara Cremolini;Fotios Loupakis;Carlotta Antoniotti;S. Lonardi

  • BRAF codons 594 and 596 mutations identify a new molecular subtype of metastatic colorectal cancer at favorable prognosis

    C Cremolini;M. Di Bartolomeo;A. Amatu;C. Antoniotti

  • The Pan-Immune-Inflammation Value is a new prognostic biomarker in metastatic colorectal cancer: results from a pooled-analysis of the Valentino and TRIBE first-line trials.

    Giovanni Fucà;Vincenzo Guarini;Carlotta Antoniotti;Federica Morano

  • A phase I–II study of weekly oxaliplatin, 5-fluorouracil continuous infusion and preoperative radiotherapy in locally advanced rectal cancer

    C. Aschele;M. L. Friso;S. Pucciarelli;S. Lonardi

  • BRAF and RAS mutations as prognostic factors in metastatic colorectal cancer patients undergoing liver resection.

    Marta Schirripa;F. Bergamo;Chiara Cremolini;M. Casagrande

Frequent Co-Authors

Vittorina Zagonel
Vittorina Zagonel Mario Negri Institute for Pharmacological Research
Fotios Loupakis
Fotios Loupakis Istituto Oncologico Veneto
Alfredo Falcone
Alfredo Falcone University of Pisa
Matteo Fassan
Matteo Fassan University of Padua
Heinz-Josef Lenz
Heinz-Josef Lenz University of Southern California
Stefano Cascinu
Stefano Cascinu Vita-Salute San Raffaele University
Andrea Sartore-Bianchi
Andrea Sartore-Bianchi University of Milan
Filippo de Braud
Filippo de Braud University of Milan
Daniele Santini
Daniele Santini Università Campus Bio-Medico
Giuseppe Tonini
Giuseppe Tonini Università Campus Bio-Medico

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