World's Best Scientists 2026 revealed!

D-Index & Metrics

Biology and Biochemistry

D-Index
70
Citations
15269
World Ranking
7113
National Ranking
3268

Overview

Alan Rein is affiliated with the National Institutes of Health in the United States. Their research primarily spans the fields of Biochemistry, Genetics and Molecular Biology, Immunology and Microbiology, and Medicine. Within these disciplines, their work focuses on several subfields including Molecular Biology, Virology, Infectious Diseases, Epidemiology, and Ecology.

The scientist's main topics of study include HIV Research and Treatment, RNA and protein synthesis mechanisms, RNA Research and Splicing, HIV/AIDS drug development and treatment, Bacteriophages and microbial interactions, Lipid Membrane Structure and Behavior, and CRISPR and Genetic Engineering.

Frequent coauthors contributing to their research are:

  • Siddhartha A.K. Datta
  • Karin Musier-Forsyth
  • Jienyu Ding
  • Yun-Xing Wang
  • Kin Kui Lai

The venues in which Alan Rein has published most frequently include:

  • Viruses
  • mBio
  • bioRxiv (Cold Spring Harbor Laboratory)
  • Nature Communications
  • Biophysical Journal

Among recent publications, notable papers are:

  • "Visualizing RNA conformational and architectural heterogeneity in solution," published in 2023 in Nature Communications
  • "IFITM3 Reduces Retroviral Envelope Abundance and Function and Is Counteracted by glycoGag," published in 2020 in mBio
  • "Antiviral HIV-1 SERINC restriction factors disrupt virus membrane asymmetry," published in 2023 in Nature Communications
  • "Determining structures of RNA conformers using AFM and deep neural networks," published in 2024 in Nature
  • "HIV-1 Gag protein with or without p6 specifically dimerizes on the viral RNA packaging signal," published in 2020 in Journal of Biological Chemistry

Best Publications

  • Loss of the tight junction protein claudin-7 correlates with histological grade in both ductal carcinoma in situ and invasive ductal carcinoma of the breast

    Scott L. Kominsky;Pedram Argani;Dorian Korz;Ella Evron;Ella Evron

  • Noninfectious human immunodeficiency virus type 1 mutants deficient in genomic RNA.

    R J Gorelick;S M Nigida;J W Bess;L O Arthur

  • Nucleic-acid-chaperone activity of retroviral nucleocapsid proteins: significance for viral replication.

    Alan Rein;Louis E Henderson;Judith G Levin

  • Point mutants of Moloney murine leukemia virus that fail to package viral RNA: evidence for specific RNA recognition by a "zinc finger-like" protein sequence

    Robert J. Gorelick;Louis E. Henderson;Janet P. Hanser;Alan Rein

  • High-throughput SHAPE analysis reveals structures in HIV-1 genomic RNA strongly conserved across distinct biological states.

    Kevin A Wilkinson;Robert J Gorelick;Suzy M Vasa;Nicolas Guex

  • Myristylation site in Pr65gag is essential for virus particle formation by moloney murine leukemia virus

    Alan Rein;Melody R. McClure;Nancy R. Rice;Ronald B. Luftig

  • RNA is a structural element in retrovirus particles

    Delphine Muriaux;Jane Mirro;Demetria Harvin;Alan Rein

  • In vitro assembly properties of human immunodeficiency virus type 1 Gag protein lacking the p6 domain.

    Stephen Campbell;Alan Rein

  • Function of the cytoplasmic domain of a retroviral transmembrane protein: p15E-p2E cleavage activates the membrane fusion capability of the murine leukemia virus Env protein.

    A Rein;J Mirro;J G Haynes;S M Ernst

  • The two zinc fingers in the human immunodeficiency virus type 1 nucleocapsid protein are not functionally equivalent.

    R J Gorelick;D J Chabot;A Rein;L E Henderson

  • Modulation of HIV-like particle assembly in vitro by inositol phosphates.

    Stephen Campbell;Robert J. Fisher;Eric M. Towler;Stephen Fox

  • Sequence-Specific Binding of Human Immunodeficiency Virus Type 1 Nucleocapsid Protein to Short Oligonucleotides

    Robert J. Fisher;Alan Rein;Matthew Fivash;Maria A. Urbaneja

  • Selective and nonselective packaging of cellular RNAs in retrovirus particles.

    Samuel J. Rulli;Catherine S. Hibbert;Jane Mirro;Thoru Pederson

  • HIV-1 nucleocapsid protein induces "maturation" of dimeric retroviral RNA in vitro

    Ya-Xiong Feng;Terry D. Copeland;Louis E. Henderson;Robert J. Gorelick

  • Supramolecular organization of immature and mature murine leukemia virus revealed by electron cryo-microscopy: Implications for retroviral assembly mechanisms

    Mark Yeager;Elizabeth M. Wilson-Kubalek;Scott G. Weiner;Patrick O. Brown

  • Infectivity of Moloney murine leukemia virus defective in late assembly events is restored by late assembly domains of other retroviruses.

    Bing Yuan;Stephen Campbell;Eran Bacharach;Alan Rein

  • Interference grouping of murine leukemia viruses: A distinct receptor for the MCF-Recombinant viruses in mouse cells

    Alan Rein

  • The Human Immunodeficiency Virus Type 1 Gag Polyprotein Has Nucleic Acid Chaperone Activity: Possible Role in Dimerization of Genomic RNA and Placement of tRNA on the Primer Binding Site

    Ya-Xiong Feng;Stephen Campbell;Demetria Harvin;Bernard Ehresmann

  • Human immunodeficiency virus type 1 nucleocapsid protein reduces reverse transcriptase pausing at a secondary structure near the murine leukemia virus polypurine tract.

    W Wu;L E Henderson;T D Copeland;R J Gorelick

  • In Vitro Characterization of the Interaction between HIV-1 Gag and Human Lysyl-tRNA Synthetase

    Brandie J. Kovaleski;Robert Kennedy;Minh K. Hong;Siddhartha A. Datta

Frequent Co-Authors

Judith G. Levin
Judith G. Levin National Institutes of Health
Robert J. Gorelick
Robert J. Gorelick National Institutes of Health
Kunio Nagashima
Kunio Nagashima National Institutes of Health
Mathias Lösche
Mathias Lösche Carnegie Mellon University
Robert J. Fisher
Robert J. Fisher Science Applications International Corporation (United States)
Karin Musier-Forsyth
Karin Musier-Forsyth The Ohio State University
Stephen Oroszlan
Stephen Oroszlan National Institutes of Health
Mark Yeager
Mark Yeager University of Miami
Saraswati Sukumar
Saraswati Sukumar Johns Hopkins University School of Medicine
Angelo M. De Marzo
Angelo M. De Marzo Johns Hopkins University School of Medicine

If you think any of the details on this page are incorrect, let us know.

Report an issue

We appreciate your kind effort to assist us to improve this page, it would be helpful providing us with as much detail as possible in the text box below:

Best Scientists Citing Alan Rein

Trending Scientists

Recently Published Articles