2012 - Fellow of the American Association for the Advancement of Science (AAAS)
Kevin M. Weeks focuses on RNA, Nucleic acid structure, Primer extension, Computational biology and Base pair. His RNA research includes themes of Stereochemistry, Protein secondary structure and Nucleotide. As a part of the same scientific study, Kevin M. Weeks usually deals with the Nucleic acid structure, concentrating on Biological system and frequently concerns with Crystallography and Ribosome.
Kevin M. Weeks has included themes like Nucleic acid and Massive parallel sequencing in his Primer extension study. His studies in Computational biology integrate themes in fields like Non-coding RNA, Small molecule, Regulation of gene expression, RNA-binding protein and Ribozyme. As a part of the same scientific family, he mostly works in the field of Base pair, focusing on Helix and, on occasion, Protein recognition, Plasma protein binding and Base sequence.
His primary scientific interests are in RNA, Nucleic acid structure, Computational biology, Genetics and Nucleotide. His RNA research incorporates themes from Base pair, Stereochemistry and Intron. His Base pair research is multidisciplinary, relying on both Helix and Protein secondary structure.
His Nucleic acid structure study incorporates themes from Biophysics, Genome, Molecular biology, Messenger RNA and Nucleic acid secondary structure. The study incorporates disciplines such as Ribosomal RNA, Reverse transcriptase, Massive parallel sequencing and Bioinformatics in addition to Computational biology. His studies deal with areas such as Reagent, Protein tertiary structure, Molecule, RNase P and Transfer RNA as well as Nucleotide.
Kevin M. Weeks mostly deals with RNA, Nucleic acid structure, Computational biology, Biophysics and Messenger RNA. The concepts of his RNA study are interwoven with issues in Genome, Nucleotide, Small molecule, Cell biology and Binding site. His Nucleic acid structure research is multidisciplinary, incorporating perspectives in Non-coding RNA, Base pair, Molecule, Primer extension and RNA-binding protein.
His Computational biology research incorporates elements of Translation, Regulation of gene expression, Reverse transcriptase and Function. In his study, Base sequence and Eukaryotic Ribosome is inextricably linked to Protein secondary structure, which falls within the broad field of Biophysics. His research in Messenger RNA intersects with topics in Complementary DNA, Nanopore and Transfer RNA.
Kevin M. Weeks mainly focuses on RNA, Computational biology, Nucleic acid structure, Reverse transcriptase and Massive parallel sequencing. His RNA research is multidisciplinary, relying on both Genome, k-mer, Conserved sequence, Sequence motif and Small molecule. His Computational biology study combines topics from a wide range of disciplines, such as Non-coding RNA, Nucleotide, Homology, Regulation of gene expression and Molecular Sequence Annotation.
His study in Nucleic acid structure is interdisciplinary in nature, drawing from both Messenger RNA, RNA-binding protein and RNase MRP. His Messenger RNA study combines topics in areas such as Base pair, Regulatory sequence, Molecular Probe Techniques and Protein secondary structure. Kevin M. Weeks combines subjects such as DNA Mutational Analysis, Nucleic acid and Bioinformatics with his study of Reverse transcriptase.
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Architecture and secondary structure of an entire HIV-1 RNA genome
Joseph M. Watts;Kristen K. Dang;Robert J. Gorelick;Christopher W. Leonard.
RNA structure analysis at single nucleotide resolution by selective 2'-hydroxyl acylation and primer extension (SHAPE).
Edward J. Merino;Kevin A. Wilkinson;Jennifer L. Coughlan;Kevin M. Weeks.
Journal of the American Chemical Society (2005)
Selective 2'-hydroxyl acylation analyzed by primer extension (SHAPE): quantitative RNA structure analysis at single nucleotide resolution.
Kevin A Wilkinson;Edward J Merino;Kevin M Weeks.
Nature Protocols (2006)
Accurate SHAPE-directed RNA structure determination
Katherine E. Deigan;Tian W. Li;David H. Mathews;Kevin M. Weeks.
Proceedings of the National Academy of Sciences of the United States of America (2009)
Fragments of the HIV-1 Tat protein specifically bind TAR RNA
Kevin M. Weeks;Christophe Ampe;Steve C. Schultz;Thomas A. Steitz.
RNA recognition by Tat-derived peptides: Interaction in the major groove?
Kevin M. Weeks;Donald M. Crothers.
High-throughput SHAPE analysis reveals structures in HIV-1 genomic RNA strongly conserved across distinct biological states.
Kevin A Wilkinson;Robert J Gorelick;Suzy M Vasa;Nicolas Guex.
PLOS Biology (2008)
RNA motif discovery by SHAPE and mutational profiling (SHAPE-MaP)
Nathan A Siegfried;Steven Busan;Greggory M Rice;Julie A E Nelson.
Nature Methods (2014)
A fast-acting reagent for accurate analysis of RNA secondary and tertiary structure by SHAPE chemistry.
Stefanie A. Mortimer;Kevin M. Weeks.
Journal of the American Chemical Society (2007)
Advances in RNA structure analysis by chemical probing.
Kevin M Weeks.
Current Opinion in Structural Biology (2010)
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