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Molecular Biology

D-Index
66
Citations
27184
World Ranking
1598
National Ranking
808

Overview

Alan D. Frankel is affiliated with the University of California, San Francisco in the United States. Their research spans across fields primarily focused on Biochemistry, Genetics and Molecular Biology, as well as Immunology and Microbiology.

Their scientific output includes work in several subfields such as Molecular Biology, Virology, Immunology, Cancer Research, and Radiology, Nuclear Medicine and Imaging. Their research topics have addressed areas including HIV Research and Treatment, RNA Research and Splicing, interferon and immune responses, Nuclear Structure and Function, Ubiquitin and proteasome pathways, RNA and protein synthesis mechanisms, and RNA modifications and cancer.

Alan D. Frankel has published in a range of journals, with frequent contributions to:

  • Molecular Cell
  • bioRxiv (Cold Spring Harbor Laboratory)
  • eLife
  • Science Advances
  • Cell Reports

Some recent publications include:

  • Phosphoregulation of Phase Separation by the SARS-CoV-2 N Protein Suggests a Biophysical Basis for its Dual Functions (2020, Molecular Cell)
  • A Quantitative Genetic Interaction Map of HIV Infection (2020, Molecular Cell)
  • Global post-translational modification profiling of HIV-1-infected cells reveals mechanisms of host cellular pathway remodeling (2022, Cell Reports)
  • Enhanced NF-κB activation via HIV-1 Tat-TRAF6 cross-talk (2024, Science Advances)
  • Functional and structural segregation of overlapping helices in HIV-1 (2022, eLife)

Frequent coauthors in their research are:

  • Maliheh Safari
  • Erik Verschueren
  • Michael Shales
  • David C. Crosby
  • Alexander Marson

Best Publications

  • A SARS-CoV-2 protein interaction map reveals targets for drug repurposing.

    David E. Gordon;Gwendolyn M. Jang;Mehdi Bouhaddou;Jiewei Xu

  • Cellular uptake of the tat protein from human immunodeficiency virus

    Alan D. Frankel;Carl O. Pabo

  • HIV-1: fifteen proteins and an RNA.

    Alan D. Frankel;John A. T. Young

  • Arginine-mediated RNA recognition: the arginine fork.

    Barbara J. Calnan;Bruce Tidor;Sara Biancalana;Derek Hudson

  • Global landscape of HIV-human protein complexes

    Stefanie Jäger;Peter Cimermancic;Peter Cimermancic;Natali Gulbahce;Natali Gulbahce;Jeffrey R. Johnson;Jeffrey R. Johnson;Jeffrey R. Johnson

  • α Helix-RNA Major Groove Recognition in an HIV-1 Rev Peptide-RRE RNA Complex

    John L. Battiste;Hongyuan Mao;N. Sambasiva Rao;Ruoying Tan

  • Conformation of the TAR RNA-arginine complex by NMR spectroscopy

    Joseph D. Puglisi;Ruoying Tan;Barbara J. Calnan;Alan D. Frankel

  • Tat protein from human immunodeficiency virus forms a metal-linked dimer

    Alan D. Frankel;David S. Bredt;Carl O. Pabo

  • Endocytosis and targeting of exogenous HIV-1 Tat protein.

    D.A. Mann;A.D. Frankel

  • Host Cell Factors in HIV Replication: Meta-Analysis of Genome-Wide Studies

    Frederic D. Bushman;Nirav Malani;Jason Fernandes;Jason Fernandes;Iván D'Orso;Iván D'Orso

  • The role of Tat in the human immunodeficiency virus life cycle indicates a primary effect on transcriptional elongation.

    Mark B. Feinberg;David Baltimore;Alan D. Frankel

  • Solution Structure of a Bovine Immunodeficiency Virus Tat-TAR Peptide-RNA Complex

    Joseph D. Puglisi;Lily Chen;Scott Blanchard;Alan D. Frankel

  • Analysis of arginine-rich peptides from the HIV Tat protein reveals unusual features of RNA-protein recognition.

    Barbara J. Calnan;Sara Biancalana;Derek Hudson;Alan D. Frankel

  • Metal-dependent folding of a single zinc finger from transcription factor IIIA

    Alan D. Frankel;Jeremy M. Berg;Carl O. Pabo

  • Inhibition of antigen-induced lymphocyte proliferation by Tat protein from HIV-1

    Raphael P. Viscidi;Kumudini Mayur;Howard M. Lederman;Alan D. Frankel

  • HIV-1 Tat protein trans-activates transcription in vitro

    Robert A. Marciniak;Barbara J. Calnan;Alan D. Frankel;Phillip A. Sharp

  • RNA recognition by an isolated α helix

    Ruoying Tan;Lily Chen;Joseph A. Buettner;Derek Hudson

  • Modular structure of transcription factors: Implications for gene regulation

    Alan D. Frankel;Peter S. Kim

  • Phosphoregulation of Phase Separation by the SARS-CoV-2 N Protein Suggests a Biophysical Basis for its Dual Functions.

    Christopher R. Carlson;Jonathan B. Asfaha;Chloe M. Ghent;Conor J. Howard

  • Structural variety of arginine-rich RNA-binding peptides.

    Ruoying Tan;Alan D. Frankel

Frequent Co-Authors

Nevan J. Krogan
Nevan J. Krogan University of California, San Francisco
Jeffrey R. Johnson
Jeffrey R. Johnson Icahn School of Medicine at Mount Sinai
Alexander Marson
Alexander Marson University of California, San Francisco
Gerard Cagney
Gerard Cagney University College Dublin
Charles S. Craik
Charles S. Craik University of California, San Francisco
Ryan D. Hernandez
Ryan D. Hernandez McGill University
Sumit K. Chanda
Sumit K. Chanda Discovery Institute
Pedro Beltrao
Pedro Beltrao European Bioinformatics Institute

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