His scientific interests lie mostly in DNA, Zinc finger, Genetics, DNA-binding protein and Stereochemistry. The various areas that Carl O. Pabo examines in his DNA study include High-mobility group, Peptide sequence, Gene, Protein structure and Binding site. Carl O. Pabo combines subjects such as Phage display and Liaison with his study of Zinc finger.
His Phage display research includes elements of Zinc finger nuclease, Protein–DNA interaction and Computational biology. In his research, Carl O. Pabo undertakes multidisciplinary study on Genetics and Histone octamer. His DNA-binding protein research is multidisciplinary, relying on both Mutation, Base pair, DNA binding site and Conserved sequence.
Carl O. Pabo focuses on Zinc finger, DNA, Genetics, Biochemistry and DNA-binding protein. His Zinc finger research is multidisciplinary, incorporating perspectives in Phage display, Computational biology and Binding site. His DNA research integrates issues from Crystallography, Gene, Stereochemistry, Repressor and Protein structure.
His Genetics study integrates concerns from other disciplines, such as Docking and Cell biology. Carl O. Pabo has included themes like Combinatorial chemistry and TATA box in his Biochemistry study. The DNA-binding protein study combines topics in areas such as Protein dna, Peptide sequence, Immediate early protein and Fusion protein.
Carl O. Pabo mainly focuses on Zinc finger, Genetics, Protein–DNA interaction, Zinc finger nuclease and Computational biology. His research is interdisciplinary, bridging the disciplines of DNA-binding protein and Zinc finger. His DNA-binding protein study combines topics in areas such as Cooperative binding, Immediate early protein, Stereochemistry and Fungal protein.
His research integrates issues of Effector and Cell biology in his study of Genetics. His study focuses on the intersection of Protein–DNA interaction and fields such as DNA-binding domain with connections in the field of HMG-box, Crystallography, DNA binding site and Protein design. His research investigates the connection between Computational biology and topics such as Gene that intersect with issues in DNA.
Zinc finger, Repressor, Transcription factor, Computational biology and Genetics are his primary areas of study. Zinc finger is a primary field of his research addressed under Gene. His study in the field of Recognition sequence, Human genome and Regulation of gene expression is also linked to topics like DNA microarray.
His Signal transduction research incorporates elements of Thyroid hormone receptor, Psychological repression and Cancer research. He integrates many fields, such as Protein engineering, Peptide library, Peptide sequence, Function, DNA-binding protein and Shuffling, in his works. Peptide library and Recombinant DNA are frequently intertwined in his study.
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Transcription factors: structural families and principles of DNA recognition
Carl O. Pabo;Robert T. Sauer.
Annual Review of Biochemistry (1992)
Protein-DNA Recognition
Carl O. Pabo;Robert T. Sauer.
Annual Review of Biochemistry (1984)
DNA recognition by Cys2His2 zinc finger proteins.
Scot A. Wolfe;Lena Nekludova;Carl O. Pabo.
Annual Review of Biophysics and Biomolecular Structure (2000)
Design and selection of novel Cys2His2 zinc finger proteins.
Carl O. Pabo;Ezra Peisach;Robert A. Grant.
Annual Review of Biochemistry (2001)
Crystal structure of a five-finger GLI-DNA complex: new perspectives on zinc fingers
Nikola P. Pavletich;Carl O. Pabo.
Science (1993)
General strategy for selecting high-affinity zinc finger proteins for diverse DNA target sites
Harvey A. Greisman;Carl O. Pabo.
Science (1999)
Basis for recognition of cisplatin-modified DNA by high-mobility-group proteins.
Uta-Maria Ohndorf;Mark A. Rould;Mark A. Rould;Qing He;Carl O. Pabo.
Nature (1999)
Zinc finger phage: affinity selection of fingers with new DNA-binding specificities
Edward J. Rebar;Carl O. Pabo.
Science (1994)
The DNA-binding domain of p53 contains the four conserved regions and the major mutation hot spots.
N P Pavletich;K A Chambers;C O Pabo.
Genes & Development (1993)
Tat protein from human immunodeficiency virus forms a metal-linked dimer
Alan D. Frankel;David S. Bredt;Carl O. Pabo.
Science (1988)
Seoul National University
MIT
University of Massachusetts Medical School
University of California, San Francisco
MIT
Harvard University
Sangamo BioSciences (United States)
University of California, Berkeley
MIT
University of California, San Francisco
Profile was last updated on December 6th, 2021.
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