D-Index & Metrics Best Publications

D-Index & Metrics

Discipline name D-index D-index (Discipline H-index) only includes papers and citation values for an examined discipline in contrast to General H-index which accounts for publications across all disciplines. Citations Publications World Ranking National Ranking
Genetics and Molecular Biology D-index 46 Citations 19,500 50 World Ranking 4294 National Ranking 2001

Overview

What is he best known for?

The fields of study he is best known for:

  • DNA
  • Gene
  • Transcription factor

His scientific interests lie mostly in DNA, Zinc finger, Genetics, DNA-binding protein and Stereochemistry. The various areas that Carl O. Pabo examines in his DNA study include High-mobility group, Peptide sequence, Gene, Protein structure and Binding site. Carl O. Pabo combines subjects such as Phage display and Liaison with his study of Zinc finger.

His Phage display research includes elements of Zinc finger nuclease, Protein–DNA interaction and Computational biology. In his research, Carl O. Pabo undertakes multidisciplinary study on Genetics and Histone octamer. His DNA-binding protein research is multidisciplinary, relying on both Mutation, Base pair, DNA binding site and Conserved sequence.

His most cited work include:

  • Transcription factors: structural families and principles of DNA recognition (1228 citations)
  • Protein-DNA Recognition (1222 citations)
  • DNA recognition by Cys2His2 zinc finger proteins. (756 citations)

What are the main themes of his work throughout his whole career to date?

Carl O. Pabo focuses on Zinc finger, DNA, Genetics, Biochemistry and DNA-binding protein. His Zinc finger research is multidisciplinary, incorporating perspectives in Phage display, Computational biology and Binding site. His DNA research integrates issues from Crystallography, Gene, Stereochemistry, Repressor and Protein structure.

His Genetics study integrates concerns from other disciplines, such as Docking and Cell biology. Carl O. Pabo has included themes like Combinatorial chemistry and TATA box in his Biochemistry study. The DNA-binding protein study combines topics in areas such as Protein dna, Peptide sequence, Immediate early protein and Fusion protein.

He most often published in these fields:

  • Zinc finger (52.86%)
  • DNA (45.71%)
  • Genetics (37.14%)

What were the highlights of his more recent work (between 2002-2005)?

  • Zinc finger (52.86%)
  • Genetics (37.14%)
  • Protein–DNA interaction (12.86%)

In recent papers he was focusing on the following fields of study:

Carl O. Pabo mainly focuses on Zinc finger, Genetics, Protein–DNA interaction, Zinc finger nuclease and Computational biology. His research is interdisciplinary, bridging the disciplines of DNA-binding protein and Zinc finger. His DNA-binding protein study combines topics in areas such as Cooperative binding, Immediate early protein, Stereochemistry and Fungal protein.

His research integrates issues of Effector and Cell biology in his study of Genetics. His study focuses on the intersection of Protein–DNA interaction and fields such as DNA-binding domain with connections in the field of HMG-box, Crystallography, DNA binding site and Protein design. His research investigates the connection between Computational biology and topics such as Gene that intersect with issues in DNA.

Between 2002 and 2005, his most popular works were:

  • Highly specific zinc finger proteins obtained by directed domain shuffling and cell-based selection (169 citations)
  • Zinc-finger protein-targeted gene regulation: Genomewide single-gene specificity (164 citations)
  • Repression of vascular endothelial growth factor A in glioblastoma cells using engineered zinc finger transcription factors. (69 citations)

In his most recent research, the most cited papers focused on:

  • Gene
  • DNA
  • Transcription factor

Zinc finger, Repressor, Transcription factor, Computational biology and Genetics are his primary areas of study. Zinc finger is a primary field of his research addressed under Gene. His study in the field of Recognition sequence, Human genome and Regulation of gene expression is also linked to topics like DNA microarray.

His Signal transduction research incorporates elements of Thyroid hormone receptor, Psychological repression and Cancer research. He integrates many fields, such as Protein engineering, Peptide library, Peptide sequence, Function, DNA-binding protein and Shuffling, in his works. Peptide library and Recombinant DNA are frequently intertwined in his study.

This overview was generated by a machine learning system which analysed the scientist’s body of work. If you have any feedback, you can contact us here.

Best Publications

Transcription factors: structural families and principles of DNA recognition

Carl O. Pabo;Robert T. Sauer.
Annual Review of Biochemistry (1992)

1989 Citations

Protein-DNA Recognition

Carl O. Pabo;Robert T. Sauer.
Annual Review of Biochemistry (1984)

1969 Citations

DNA recognition by Cys2His2 zinc finger proteins.

Scot A. Wolfe;Lena Nekludova;Carl O. Pabo.
Annual Review of Biophysics and Biomolecular Structure (2000)

1219 Citations

Design and selection of novel Cys2His2 zinc finger proteins.

Carl O. Pabo;Ezra Peisach;Robert A. Grant.
Annual Review of Biochemistry (2001)

963 Citations

Crystal structure of a five-finger GLI-DNA complex: new perspectives on zinc fingers

Nikola P. Pavletich;Carl O. Pabo.
Science (1993)

915 Citations

General strategy for selecting high-affinity zinc finger proteins for diverse DNA target sites

Harvey A. Greisman;Carl O. Pabo.
Science (1999)

915 Citations

Basis for recognition of cisplatin-modified DNA by high-mobility-group proteins.

Uta-Maria Ohndorf;Mark A. Rould;Mark A. Rould;Qing He;Carl O. Pabo.
Nature (1999)

693 Citations

Zinc finger phage: affinity selection of fingers with new DNA-binding specificities

Edward J. Rebar;Carl O. Pabo.
Science (1994)

681 Citations

The DNA-binding domain of p53 contains the four conserved regions and the major mutation hot spots.

N P Pavletich;K A Chambers;C O Pabo.
Genes & Development (1993)

663 Citations

Tat protein from human immunodeficiency virus forms a metal-linked dimer

Alan D. Frankel;David S. Bredt;Carl O. Pabo.
Science (1988)

643 Citations

Best Scientists Citing Carl O. Pabo

Robert T. Sauer

Robert T. Sauer

MIT

Publications: 77

Edward J. Rebar

Edward J. Rebar

Sangamo BioSciences (United States)

Publications: 65

Fyodor D. Urnov

Fyodor D. Urnov

University of California, Berkeley

Publications: 58

Philip D. Gregory

Philip D. Gregory

Sangamo BioSciences (United States)

Publications: 57

Carlos F. Barbas

Carlos F. Barbas

Scripps Research Institute

Publications: 46

David J. Segal

David J. Segal

University of California, Davis

Publications: 43

J. Keith Joung

J. Keith Joung

Harvard University

Publications: 43

David R. Liu

David R. Liu

Harvard University

Publications: 42

Jeffrey C. Miller

Jeffrey C. Miller

Sangamo BioSciences (United States)

Publications: 42

Michael C. Holmes

Michael C. Holmes

Ambys Medicines

Publications: 35

Viktor Brabec

Viktor Brabec

Czech Academy of Sciences

Publications: 31

Mark Ptashne

Mark Ptashne

Memorial Sloan Kettering Cancer Center

Publications: 30

Gary D. Stormo

Gary D. Stormo

Washington University in St. Louis

Publications: 28

Rolf Boelens

Rolf Boelens

Utrecht University

Publications: 28

Robert Kaptein

Robert Kaptein

Utrecht University

Publications: 27

Profile was last updated on December 6th, 2021.
Research.com Ranking is based on data retrieved from the Microsoft Academic Graph (MAG).
The ranking d-index is inferred from publications deemed to belong to the considered discipline.

If you think any of the details on this page are incorrect, let us know.

Contact us
Something went wrong. Please try again later.