What is he best known for?
The fields of study he is best known for:
The scientist’s investigation covers issues in DNA, Stereochemistry, Cisplatin, Platinum and Guanine.
The DNA study combines topics in areas such as Bifunctional, Adduct and Circular dichroism.
His Stereochemistry research includes elements of Gel electrophoresis, Base pair, Ligand and Ruthenium.
Viktor Brabec has included themes like Mechanism of action, Platinum Compound, DNA damage and Cytotoxicity in his Cisplatin study.
His Platinum research is multidisciplinary, relying on both Dna interaction, Combinatorial chemistry, Pharmacology, Antitumor activity and Chloride.
Viktor Brabec has researched Guanine in several fields, including Ethidium bromide, Ethylenediamine and Molecule, Hydrogen bond.
His most cited work include:
- DNA binding mode of ruthenium complexes and relationship to tumor cell toxicity. (288 citations)
- Modifications of DNA by platinum complexes. Relation to resistance of tumors to platinum antitumor drugs. (272 citations)
- DNA interactions of monofunctional organometallic ruthenium(II) antitumor complexes in cell-free media. (266 citations)
What are the main themes of his work throughout his whole career to date?
DNA, Stereochemistry, Cisplatin, Platinum and Biochemistry are his primary areas of study.
His DNA study also includes fields such as
- Adduct which intersects with area such as Nucleotide,
- Ruthenium most often made with reference to Guanine.
His research investigates the connection between Stereochemistry and topics such as Ligand that intersect with issues in Medicinal chemistry.
Viktor Brabec interconnects Cancer cell, Cell culture, DNA repair and Cytotoxicity in the investigation of issues within Cisplatin.
His biological study spans a wide range of topics, including Prodrug, Cancer research and Mechanism of action.
The concepts of his Platinum study are interwoven with issues in Combinatorial chemistry, Molecule, Oxaliplatin and Polarography.
He most often published in these fields:
- DNA (67.73%)
- Stereochemistry (59.73%)
- Cisplatin (44.27%)
What were the highlights of his more recent work (between 2016-2021)?
- DNA (67.73%)
- Cisplatin (44.27%)
- Stereochemistry (59.73%)
In recent papers he was focusing on the following fields of study:
Viktor Brabec spends much of his time researching DNA, Cisplatin, Stereochemistry, Cancer cell and Combinatorial chemistry.
His DNA research includes themes of Biophysics, Platinum, Intercalation and Amine gas treating.
His studies deal with areas such as Cell culture, Moiety, Ligand and Cytotoxicity as well as Cisplatin.
His Stereochemistry research is multidisciplinary, incorporating elements of IC50 and Structural motif.
His Cancer cell research incorporates elements of Prodrug, Cancer research, DNA damage and Mechanism of action.
His work deals with themes such as Selectivity, Biological activity, Antimicrobial and Coordination complex, which intersect with Combinatorial chemistry.
Between 2016 and 2021, his most popular works were:
- Cytotoxic platinum coordination compounds. DNA binding agents (50 citations)
- Towards Novel Photodynamic Anticancer Agents Generating Superoxide Anion Radicals: A Cyclometalated IrIII Complex Conjugated to a Far‐Red Emitting Coumarin (45 citations)
- Ruthenium coordination compounds of biological and biomedical significance. DNA binding agents (39 citations)
In his most recent research, the most cited papers focused on:
Viktor Brabec mainly focuses on DNA, Cisplatin, Combinatorial chemistry, Cytotoxicity and Cancer cell.
Viktor Brabec is involved in the study of DNA that focuses on Topoisomerase in particular.
His Combinatorial chemistry research also works with subjects such as
- DNA damage which connect with Moiety, Minor groove, Sequence and Cleave,
- Coordination complex which connect with Platinum, Cell signaling and Ruthenium.
His research integrates issues of Cytotoxic T cell, Cell culture and Stereochemistry in his study of Cytotoxicity.
His Stereochemistry research incorporates themes from IC50 and Ligand.
His Cancer cell study combines topics from a wide range of disciplines, such as Prodrug and Cancer research.
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