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Chemistry

D-Index
41
Citations
5748
World Ranking
17789
National Ranking
734

Overview

José Ruiz is a researcher affiliated with the University of Murcia in Spain, with a focus on interdisciplinary studies spanning medicine, chemistry, and materials science. Their work integrates aspects of organic chemistry, materials chemistry, biomedical engineering, pulmonary and respiratory medicine, and oncology.

Their research primarily addresses several key topics, including:

  • Nanoplatforms for cancer theranostics
  • Metal complexes synthesis and properties
  • Photodynamic therapy research studies
  • Click chemistry and applications
  • Luminescence and fluorescent materials
  • Synthesis and biological activity
  • Synthesis and biological evaluation

José Ruiz has contributed numerous publications to a variety of scientific venues. The most frequent publication forums include:

  • Inorganic Chemistry Frontiers
  • Journal of Medicinal Chemistry
  • Inorganic Chemistry
  • Dalton Transactions
  • Chemical Communications

Frequent collaborations have been established with several co-authors, such as:

  • Enrique Ortega
  • Gloria Vigueras
  • Viktor Brabec
  • Vicente Marchán
  • Delia Bautista

Recent papers by José Ruiz include:

  • COUPY Coumarins as Novel Mitochondria-Targeted Photodynamic Therapy Anticancer Agents, 2021, Journal of Medicinal Chemistry
  • A photoactivated Ir(iii) complex targets cancer stem cells and induces secretion of damage-associated molecular patterns in melanoma cells characteristic of immunogenic cell death, 2021, Inorganic Chemistry Frontiers
  • A near-infrared light-activatable Ru(ii)-coumarin photosensitizer active under hypoxic conditions, 2023, Chemical Science
  • Targeting translation: a promising strategy for anticancer metallodrugs, 2021, Coordination Chemistry Reviews
  • Novel 2-(5-Arylthiophen-2-yl)-benzoazole Cyclometalated Iridium(III) dppz Complexes Exhibit Selective Phototoxicity in Cancer Cells by Lysosomal Damage and Oncosis, 2023, Journal of Medicinal Chemistry

Best Publications

  • Cyclometalated iridium(III) luminescent complexes in therapy and phototherapy

    Ana Zamora;Gloria Vigueras;Venancio Rodríguez;M. Dolores Santana

  • Anticancer cyclometalated complexes of platinum group metals and gold

    Natalia Cutillas;Gorakh S. Yellol;Concepción de Haro;Consuelo Vicente

  • Towards Novel Photodynamic Anticancer Agents Generating Superoxide Anion Radicals: A Cyclometalated IrIII Complex Conjugated to a Far‐Red Emitting Coumarin

    Vojtech Novohradsky;Anna Rovira;Cormac Hally;Alex Galindo

  • Novel C,N-Cyclometalated Benzimidazole Ruthenium(II) and Iridium(III) Complexes as Antitumor and Antiangiogenic Agents: A Structure–Activity Relationship Study

    Jyoti Yellol;Sergio A. Pérez;Alicia Buceta;Gorakh Yellol

  • Structural and magnetic studies of a syn-anti carboxylate-bridged helix-like chain copper(II) complex

    Enrique Colacio;Jose Manuel Dominguez-Vera;Jean Pierre Costes;Raikko Kivekas

  • New palladium(II) and platinum(II) complexes with the model nucleobase 1-methylcytosine: antitumor activity and interactions with DNA.

    José Ruiz;Natalia Cutillas;Consuelo Vicente;Maria Dolores Villa

  • On the antitumor properties of novel cyclometalated benzimidazole Ru(II), Ir(III) and Rh(III) complexes

    Gorakh S. Yellol;Antonio Donaire;Jyoti G. Yellol;Vera Vasylyeva

  • Palladium(II) and platinum(II) organometallic complexes with the model nucleobase anions of thymine, uracil, and cytosine : Antitumor activity and interactions with DNA of the platinum compounds○

    José Ruiz;Julia Lorenzo;Laura Sanglas;Natalia Cutillas

  • A quasi-tetrahedral tetracopper cluster with syn-anti bridging carboxylate groups: crystal and molecular structure and magnetic properties

    Enrique Colacio;Jean Pierre Costes;Raikko Kivekas;Jean Pierre Laurent

  • Falcipain Inhibitors: Optimization Studies of the 2-Pyrimidinecarbonitrile Lead Series†

    Jose M. Coterón;David Catterick;Julia Castro;María J. Chaparro

  • Novel Bis-C,N-Cyclometalated Iridium(III) Thiosemicarbazide Antitumor Complexes: Interactions with Human Serum Albumin and DNA, and Inhibition of Cathepsin B

    José Ruiz;Consuelo Vicente;Concepción de Haro;Delia Bautista

  • Palladium(II) and platinum(II) organometallic complexes with 4,7-dihydro-5-methyl-7-oxo[1,2,4]triazolo[1,5-a]pyrimidine. Antitumor activity of the platinum compounds.

    José Ruiz;María Dolores Villa;Natalia Cutillas;Gregorio López

  • New palladium(II) and platinum(II) complexes with 9-aminoacridine: structures, luminiscence, theoretical calculations, and antitumor activity.

    José Ruiz;Julia Lorenzo;Consuelo Vicente;Gregorio López

  • Novel C,N-chelate rhodium(III) and iridium(III) antitumor complexes incorporating a lipophilic steroidal conjugate and their interaction with DNA.

    José Ruiz;Venancio Rodríguez;Natalia Cutillas;Katia G. Samper

  • Can a single C–H⋯F–C hydrogen bond make a difference? Assessing the H⋯F bond strength from 2-D 1H-19F CP/MAS NMR

    Gerhard Althoff;José Ruiz;Venancio Rodríguez;Gregorio López

  • Synthesis of 2-Pyridyl-benzimidazole Iridium(III), Ruthenium(II), and Platinum(II) Complexes. Study of the Activity as Inhibitors of Amyloid-β Aggregation and Neurotoxicity Evaluation

    Gorakh S. Yellol;Jyoti G. Yellol;Vijaya B. Kenche;Xiang Ming Liu

  • A Potent Ruthenium(II) Antitumor Complex Bearing a Lipophilic Levonorgestrel Group

    José Ruiz;Venancio Rodríguez;Natalia Cutillas;Arturo Espinosa

  • Synthesis, structural characterization, and reactivity toward weak, protic electrophiles of di-.mu.-hydroxytetrakis(pentafluorophenyl)dipalladate(2-)

    Gregorio. Lopez;Jose. Ruiz;Gabriel. Garcia;Consuelo. Vicente

  • Hydroxo and azolate derivatives of pentafluorophenyl-nickel(II) complexes. Crystal structure of [NBu4]2[{Ni(C6F5)2(.mu.-OH)}2] and [NBu4]2[{Ni(C6F5)2}2(.mu.-OH)(.mu.-pyrazolato)]

    Gregorio Lopez;Gabriel Garcia;Gregorio Sanchez;Joaquin Garcia

  • A copper-and amine-free sonogashira reaction of aryl halides catalyzed by 1,3,5-triaza-7-phosphaadamantane palladium systems

    José Ruiz;Natalia Cutillas;Francisco Lopez;Gregorio Lopez

  • Ruthenium-containing P450 inhibitors for dual enzyme inhibition and DNA damage

    Ana Zamora;Catherine A. Denning;David K. Heidary;Erin Wachter

  • Synthesis and characterization of arylamide-bridged binuclear palladium(II) complexes. Crystal structure of anti-[[Pd(C6F5)(t-BuNC)(.mu.-NHPh)]2]

    Jose Ruiz;M. Teresa Martinez;Consuelo Vicente;Gabriel Garcia

  • Reactivity of [{M(C6F5)2(μ-OH)}2]2- (M = Pd or Pt) toward Aromatic Amines and Malononitrile

    José Ruiz;Venancio Rodríguez;Gregorio López;Jaume Casabó

Frequent Co-Authors

Christoph Janiak
Christoph Janiak Heinrich Heine University Düsseldorf
Viktor Brabec
Viktor Brabec Czech Academy of Sciences
Pascual Parrilla
Pascual Parrilla University of Murcia
Peter B. Hitchcock
Peter B. Hitchcock University of Sussex
Peter M. Maitlis
Peter M. Maitlis University of Sheffield
Jana Kasparkova
Jana Kasparkova Czech Academy of Sciences
Juan A. Hermoso
Juan A. Hermoso Spanish National Research Council
Brian E. Mann
Brian E. Mann University of Sheffield
Ibon Alkorta
Ibon Alkorta Spanish National Research Council
Virtudes Moreno
Virtudes Moreno University of Barcelona

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