What is she best known for?
The fields of study she is best known for:
DNA, Stereochemistry, Platinum, Adduct and Nucleotide excision repair are her primary areas of study.
Her studies in DNA integrate themes in fields like Guanine and Cytotoxicity.
The Cis–trans isomerism research Jana Kasparkova does as part of her general Stereochemistry study is frequently linked to other disciplines of science, such as Ligand, therefore creating a link between diverse domains of science.
Her Platinum research incorporates themes from Coordination complex and Pharmacology.
The Adduct study which covers Oligonucleotide that intersects with Methylamine, Thiazole, Proton NMR, Thymine and Comet assay.
Her research investigates the connection with Nucleotide excision repair and areas like Platinum Compound which intersect with concerns in DNA polymerase.
Her most cited work include:
- Modifications of DNA by platinum complexes. Relation to resistance of tumors to platinum antitumor drugs. (272 citations)
- A potent cytotoxic photoactivated platinum complex (224 citations)
- DNA modifications by a novel bifunctional trinuclear platinum phase I anticancer agent. (164 citations)
What are the main themes of her work throughout her whole career to date?
Jana Kasparkova mostly deals with DNA, Stereochemistry, Platinum, Biochemistry and Cytotoxicity.
Her biological study spans a wide range of topics, including Bifunctional, Adduct and Guanine.
Her Stereochemistry study incorporates themes from DNA polymerase, Molecule, Ligand and Ruthenium.
Her work carried out in the field of Platinum brings together such families of science as Combinatorial chemistry, Oxaliplatin and Pharmacology.
Her work on Antitumor activity, HMG-box, Electrophoretic mobility shift assay and Gel electrophoresis as part of general Biochemistry study is frequently connected to DNA clamp, therefore bridging the gap between diverse disciplines of science and establishing a new relationship between them.
Her study in Cytotoxicity is interdisciplinary in nature, drawing from both Cancer cell, Cytotoxic T cell, Cell culture and Molecular biology.
She most often published in these fields:
- DNA (74.07%)
- Stereochemistry (66.67%)
- Platinum (30.16%)
What were the highlights of her more recent work (between 2018-2021)?
- DNA (74.07%)
- Medicinal chemistry (8.99%)
- Cancer cell (20.63%)
In recent papers she was focusing on the following fields of study:
Her primary areas of investigation include DNA, Medicinal chemistry, Cancer cell, Tris and Cancer research.
Her DNA research is multidisciplinary, incorporating perspectives in Combinatorial chemistry, Enantiomer, Stereochemistry and Intercalation.
Her Stereochemistry research includes themes of Radical, Cleavage and Mode of action.
Her Medicinal chemistry research incorporates elements of Denticity, Ligand, 1,2,3-Triazole and Dna interaction.
Jana Kasparkova interconnects DNA damage, Mechanism of action, Moiety, Platinum and Prodrug in the investigation of issues within Cancer cell.
Her work deals with themes such as Cinnamic acid and Spheroid, which intersect with Platinum.
Between 2018 and 2021, her most popular works were:
- Towards Novel Photodynamic Anticancer Agents Generating Superoxide Anion Radicals: A Cyclometalated IrIII Complex Conjugated to a Far‐Red Emitting Coumarin (45 citations)
- A Subset of New Platinum Antitumor Agents Kills Cells by a Multimodal Mechanism of Action Also Involving Changes in the Organization of the Microtubule Cytoskeleton (14 citations)
- Molecular superoxide radical photogeneration in cancer cells by dipyridophenazine iridium( iii ) complexes (11 citations)
In her most recent research, the most cited papers focused on:
The scientist’s investigation covers issues in Cancer cell, Combinatorial chemistry, DNA, Phenylbutyrate and DNA damage.
The various areas that Jana Kasparkova examines in her Cancer cell study include Tumor microenvironment, Cancer stem cell, Cancer research and Propidium iodide.
She has included themes like Cell culture, Mechanism of action, Oxaliplatin, Cytoskeleton and Cytotoxic T cell in her Cancer research study.
Her Combinatorial chemistry research integrates issues from Reactive oxygen species, Photodynamic therapy, Superoxide and Photosensitizer.
In her research, Jana Kasparkova performs multidisciplinary study on DNA and Quinolone.
Combining a variety of fields, including Phenylbutyrate, Moiety, Prodrug and Biological activity, are what the author presents in her essays.
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