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Chemistry
Italy
2025

D-Index & Metrics

Chemistry

D-Index
81
Citations
21227
World Ranking
3293
National Ranking
58

Research.com Recognitions

  • 2025 - Research.com Chemistry in Italy Leader Award
  • 2022 - Research.com Chemistry in Italy Leader Award

Overview

Luigi Messori is affiliated with the University of Florence in Italy. Their research primarily intersects the fields of Medicine, Chemistry, and Biochemistry, Genetics and Molecular Biology. These areas are underscored by their sustained publication record across multiple specialized journals and their focus on complex biochemical systems and medicinal applications.

The scientist has a significant publication footprint in areas including Oncology, Molecular Biology, Organic Chemistry, Materials Chemistry, and Nutrition and Dietetics. Their work frequently addresses topics such as metal complexes synthesis and properties, trace elements in health, iron metabolism and disorders, advanced biosensing and bioanalysis techniques, crystallization and solubility studies, X-ray diffraction in crystallography, and ferrocene chemistry and applications.

Recent papers highlight Luigi Messori's involvement in research related to metal-based therapeutics targeting viral infections and cancer. Notable publications include:

  • "Metallo therapeutics for COVID-19. Exploiting metal-based compounds for the discovery of new antiviral drugs" (2020, Expert Opinion on Drug Discovery)
  • "A Role for Metal-Based Drugs in Fighting COVID-19 Infection? The Case of Auranofin" (2020, ACS Medicinal Chemistry Letters)
  • "ESI MS studies highlight the selective interaction of Auranofin with protein free thiols" (2020, Dalton Transactions)
  • "Reactions of Medicinal Gold(III) Compounds With Proteins and Peptides Explored by Electrospray Ionization Mass Spectrometry and Complementary Biophysical Methods" (2020, Frontiers in Chemistry)
  • "Redox proteome analysis of auranofin exposed ovarian cancer cells (A2780)" (2022, Redox Biology)

Luigi Messori collaborates frequently with a number of researchers, with a consistent record of co-authorship including:

  • Lara Massai (46 publications)
  • Damiano Cirri (25 publications)
  • Alessandro Pratesi (25 publications)
  • Tiziano Marzo (22 publications)
  • Andrea Geri (17 publications)

The scientist's research is frequently published in various academic venues, notably:

  • Dalton Transactions (14 publications)
  • The Cambridge Structural Database (7 publications)
  • Journal of Inorganic Biochemistry (6 publications)
  • Inorganic Chemistry (5 publications)
  • Molecules (4 publications)

Best Publications

  • Thioredoxin reductase: A target for gold compounds acting as potential anticancer drugs

    Alberto Bindoli;Maria Pia Rigobello;Guido Scutari;Chiara Gabbiani

  • Gold compounds as anticancer agents: Chemistry, cellular pharmacology, and preclinical studies

    Stefania Nobili;Enrico Mini;Ida Landini;Chiara Gabbiani

  • Gold(III) complexes as potential antitumor agents: solution chemistry and cytotoxic properties of some selected gold(III) compounds.

    Luigi Messori;Francesco Abbate;Giordana Marcon;Pierluigi Orioli

  • NAMI-A and KP1019/1339, Two Iconic Ruthenium Anticancer Drug Candidates Face-to-Face: A Case Story in Medicinal Inorganic Chemistry

    Enzo Alessio;Luigi Messori

  • Gold(III) Complexes with Bipyridyl Ligands: Solution Chemistry, Cytotoxicity, and DNA Binding Properties

    Giordana Marcon;Stefania Carotti;Marcella Coronnello;Luigi Messori

  • Emerging protein targets for anticancer metallodrugs: inhibition of thioredoxin reductase and cathepsin B by antitumor ruthenium(II)-arene compounds

    Angela Casini;Chiara Gabbiani;Francesca Sorrentino;Maria Pia Rigobello

  • Clioquinol, a drug for Alzheimer's disease specifically interfering with brain metal metabolism: structural characterization of its zinc(II) and copper(II) complexes.

    Massimo Di Vaira;Carla Bazzicalupi;Pierluigi Orioli;Luigi Messori

  • Gold(III) compounds as anticancer agents: Relevance of gold-protein interactions for their mechanism of action.

    Angela Casini;Christian Hartinger;Chiara Gabbiani;Enrico Mini

  • The binding properties of two antitumor ruthenium(III) complexes to apotransferrin.

    F Kratz;M Hartmann;B Keppler;L Messori

  • Metal-based drugs for malaria, trypanosomiasis and leishmaniasis: recent achievements and perspectives

    Maribel Navarro;Chiara Gabbiani;Luigi Messori;Dinorah Gambino

  • Gold complexes inhibit mitochondrial thioredoxin reductase: consequences on mitochondrial functions

    Maria Pia Rigobello;Luigi Messori;Giordana Marcon;Maria Agostina Cinellu

  • Structural and solution chemistry, antiproliferative effects, and DNA and protein binding properties of a series of dinuclear gold(III) compounds with bipyridyl ligands.

    Angela Casini;Maria Agostina Cinellu;Giovanni Minghetti;Chiara Gabbiani

  • A gold-containing drug against parasitic polyamine metabolism: the X-ray structure of trypanothione reductase from Leishmania infantum in complex with auranofin reveals a dual mechanism of enzyme inhibition.

    Andrea Ilari;Paola Baiocco;Luigi Messori;Annarita Fiorillo

  • Aluminum, copper, iron and zinc differentially alter amyloid-Aβ 1-42 aggregation and toxicity

    Silvia Bolognin;Luigi Messori;Denise Drago;Chiara Gabbiani

  • Molecular mechanisms and proposed targets for selected anticancer gold compounds.

    Angela Casini;Luigi Messori

  • A spectroscopic study of the reaction of NAMI, a novel ruthenium(III)anti-neoplastic complex, with bovine serum albumin.

    Luigi Messori;Pierluigi Orioli;Daniela Vullo;Enzo Alessio

  • Challenges associated with metal chelation therapy in Alzheimer's disease.

    Muralidhar L. Hegde;P. Bharathi;Anitha Suram;Chitra Venugopal

  • New uses for old drugs. Auranofin, a clinically established antiarthritic metallodrug, exhibits potent antimalarial effects in vitro : Mechanistic and pharmacological implications

    Anna Rosa Sannella;Angela Casini;Chiara Gabbiani;Luigi Messori

  • Gold(III) compounds as anticancer drugs

    Chiara Gabbiani;Angela Casini;Luigi Messori

  • A comparative study of aluminum(III), gallium(III), indium(III), and thallium(III) binding to human serum transferrin

    Wesley R Harris;Luigi Messori

Frequent Co-Authors

Chiara Gabbiani
Chiara Gabbiani University of Pisa
Angela Casini
Angela Casini Technical University of Munich
Antonello Merlino
Antonello Merlino University of Naples Federico II
Maria Agostina Cinellu
Maria Agostina Cinellu University of Sassari
Ivano Bertini
Ivano Bertini University of Florence
Claudio Luchinat
Claudio Luchinat University of Florence
Anna Rita Bilia
Anna Rita Bilia University of Florence
Andrea Scozzafava
Andrea Scozzafava University of Florence
Gloriano Moneti
Gloriano Moneti University of Florence
Annarosa Arcangeli
Annarosa Arcangeli University of Florence

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