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Chiara Gabbiani

Chiara Gabbiani

D-Index & Metrics

Chemistry

D-Index
51
Citations
8830
World Ranking
14003
National Ranking
476

Overview

Chiara Gabbiani is affiliated with the University of Pisa in Italy. Their research spans several intersecting fields, including chemistry, materials science, and medicine. Over the course of their career, Gabbiani has contributed to 34 publications in chemistry, 21 in materials science, and 16 in medicine.

Their subfield expertise includes organic chemistry, materials chemistry, and oncology, along with work in molecular biology and inorganic chemistry. Their core research topics focus on metal complexes synthesis and properties, ferrocene chemistry and applications, crystallization and solubility studies, X-ray diffraction in crystallography, N-heterocyclic carbenes in organic and inorganic chemistry, click chemistry and applications, and organometallic complex synthesis and catalysis.

Frequent co-authors collaborating with Gabbiani include Alessandro Pratesi, Damiano Cirri, Tarita Biver, Federica Guarra, and Ester Giorgi.

Gabbiani's publications appear regularly in several scientific venues, notably:

  • The Cambridge Structural Database
  • Inorganica Chimica Acta
  • Journal of Inorganic Biochemistry
  • Molecules
  • Angewandte Chemie International Edition

Selected recent papers authored by Gabbiani comprise:

  • "Cytotoxic Ag(I) and Au(I) NHC-carbenes bind DNA and show TrxR inhibition", 2020, Journal of Inorganic Biochemistry
  • "A focus on the biological targets for coinage metal-NHCs as potential anticancer complexes", 2021, Journal of Inorganic Biochemistry
  • "An overview of recent advancements in anticancer Pt(IV) prodrugs: New smart drug combinations, activation and delivery strategies", 2023, Inorganica Chimica Acta
  • "Mechanistic Insights Into the Anticancer Properties of the Auranofin Analog Au(PEt3)I: A Theoretical and Experimental Study", 2020, Frontiers in Chemistry
  • "124I Radiolabeling of a AuIII-NHC Complex for In Vivo Biodistribution Studies", 2020, Angewandte Chemie International Edition

Best Publications

  • Thioredoxin reductase: A target for gold compounds acting as potential anticancer drugs

    Alberto Bindoli;Maria Pia Rigobello;Guido Scutari;Chiara Gabbiani

  • Gold compounds as anticancer agents: Chemistry, cellular pharmacology, and preclinical studies

    Stefania Nobili;Enrico Mini;Ida Landini;Chiara Gabbiani

  • Emerging protein targets for anticancer metallodrugs: inhibition of thioredoxin reductase and cathepsin B by antitumor ruthenium(II)-arene compounds

    Angela Casini;Chiara Gabbiani;Francesca Sorrentino;Maria Pia Rigobello

  • Gold(III) compounds as anticancer agents: Relevance of gold-protein interactions for their mechanism of action.

    Angela Casini;Christian Hartinger;Chiara Gabbiani;Enrico Mini

  • Nanoparticles of Mg(OH)2: synthesis and application to paper conservation.

    Rodorico Giorgi;Claudio Bozzi;Luigi Dei;Chiara Gabbiani

  • Metal-based drugs for malaria, trypanosomiasis and leishmaniasis: recent achievements and perspectives

    Maribel Navarro;Chiara Gabbiani;Luigi Messori;Dinorah Gambino

  • Structural and solution chemistry, antiproliferative effects, and DNA and protein binding properties of a series of dinuclear gold(III) compounds with bipyridyl ligands.

    Angela Casini;Maria Agostina Cinellu;Giovanni Minghetti;Chiara Gabbiani

  • Aluminum, copper, iron and zinc differentially alter amyloid-Aβ 1-42 aggregation and toxicity

    Silvia Bolognin;Luigi Messori;Denise Drago;Chiara Gabbiani

  • New uses for old drugs. Auranofin, a clinically established antiarthritic metallodrug, exhibits potent antimalarial effects in vitro : Mechanistic and pharmacological implications

    Anna Rosa Sannella;Angela Casini;Chiara Gabbiani;Luigi Messori

  • Gold(III) compounds as anticancer drugs

    Chiara Gabbiani;Angela Casini;Luigi Messori

  • Chemistry, antiproliferative properties, tumor selectivity, and molecular mechanisms of novel gold(III) compounds for cancer treatment: a systematic study

    Angela Casini;Gerhard Kelter;Chiara Gabbiani;Maria Agostina Cinellu

  • Mechanisms of cytotoxicity of selected organogold(III) compounds.

    Marcella Coronnello;Enrico Mini;Barbara Caciagli;Maria Agostina Cinellu

  • ESI mass spectrometry and X-ray diffraction studies of adducts between anticancer platinum drugs and hen egg white lysozyme

    Angela Casini;Guido Mastrobuoni;Claudia Temperini;Chiara Gabbiani

  • Clioquinol decreases amyloid-beta burden and reduces working memory impairment in a transgenic mouse model of Alzheimer's disease.

    Cristina Grossi;Simona Francese;Angela Casini;Maria Cristina Rosi

  • Exploring metallodrug–protein interactions by mass spectrometry: comparisons between platinum coordination complexes and an organometallic ruthenium compound

    Angela Casini;Chiara Gabbiani;Elena Michelucci;Giuseppe Pieraccini

  • Thioredoxin reductase, an emerging target for anticancer metallodrugs. Enzyme inhibition by cytotoxic gold(III) compounds studied with combined mass spectrometry and biochemical assays

    Chiara Gabbiani;Guido Mastrobuoni;Francesca Sorrentino;Barbara Dani

  • Structural characterization, solution studies, and DFT calculations on a series of binuclear gold(III) oxo complexes: relationships to biological properties

    Chiara Gabbiani;Angela Casini;Luigi Messori;Annalisa Guerri

  • Insights on the mechanism of thioredoxin reductase inhibition by gold N-heterocyclic carbene compounds using the synthetic linear selenocysteine containing C-terminal peptide hTrxR(488-499): an ESI-MS investigation.

    Alessandro Pratesi;Chiara Gabbiani;Elena Michelucci;Mauro Ginanneschi

  • Auranofin, Et3PAuCl, and Et3PAuI Are Highly Cytotoxic on Colorectal Cancer Cells: A Chemical and Biological Study.

    Tiziano Marzo;Damiano Cirri;Chiara Gabbiani;Tania Gamberi

  • ESI–MS Characterisation of Protein Adducts of Anticancer Ruthenium(II)‐Arene PTA (RAPTA) Complexes

    Angela Casini;Guido Mastrobuoni;Wee Han Ang;Chiara Gabbiani

  • Exploring metallodrug-protein interactions by ESI mass spectrometry: the reaction of anticancer platinum drugs with horse heart cytochrome c.

    Angela Casini;Chiara Gabbiani;Guido Mastrobuoni;Luigi Messori

Frequent Co-Authors

Luigi Messori
Luigi Messori University of Florence
Angela Casini
Angela Casini Technical University of Munich
Maria Agostina Cinellu
Maria Agostina Cinellu University of Sassari
Gloriano Moneti
Gloriano Moneti University of Florence
Paul J. Dyson
Paul J. Dyson École Polytechnique Fédérale de Lausanne
Annarosa Arcangeli
Annarosa Arcangeli University of Florence
Anna Rita Bilia
Anna Rita Bilia University of Florence
Federica Chiellini
Federica Chiellini University of Pisa
Alberto Bindoli
Alberto Bindoli University of Padua
Tanja Schirmeister
Tanja Schirmeister Johannes Gutenberg University of Mainz

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