His primary areas of investigation include Biochemistry, Thioredoxin reductase, Thioredoxin, Auranofin and Glutathione. His work on Enzyme, Peroxidase and Mitochondrion as part of general Biochemistry study is frequently linked to Adrenochrome, therefore connecting diverse disciplines of science. The various areas that Alberto Bindoli examines in his Mitochondrion study include Malondialdehyde and Cytochrome P450.
Alberto Bindoli has included themes like Apoptosis, Stereochemistry, Cisplatin and Membrane permeability in his Thioredoxin reductase study. His Thioredoxin research incorporates elements of Thiol, Nicotinamide adenine dinucleotide phosphate, Inner mitochondrial membrane, Glutathione reductase and Cytosol. Glutathione and Lipid peroxidation are commonly linked in his work.
His primary scientific interests are in Biochemistry, Thioredoxin reductase, Thioredoxin, Mitochondrion and Antioxidant. His study on Biochemistry is mostly dedicated to connecting different topics, such as Biophysics. His Thioredoxin reductase study combines topics from a wide range of disciplines, such as Stereochemistry and Glutathione reductase.
His Thioredoxin research includes themes of Reactive oxygen species, Cell biology, Redox and Peroxiredoxin. Alberto Bindoli combines subjects such as ATP synthase, Membrane potential and Mitochondrial permeability transition pore with his study of Mitochondrion. His work on Lipid peroxidation and Butylated hydroxytoluene as part of general Antioxidant research is frequently linked to KEAP1, bridging the gap between disciplines.
Alberto Bindoli mostly deals with Biochemistry, Thioredoxin reductase, Thioredoxin, Antioxidant and Mitochondrion. His work on Cytosol and Gastrointestinal digestion as part of general Biochemistry study is frequently connected to Keap1 nrf2, therefore bridging the gap between diverse disciplines of science and establishing a new relationship between them. His Thioredoxin reductase research incorporates themes from Redox, Horseradish peroxidase and Glutathione reductase.
His work in Thioredoxin covers topics such as Peroxiredoxin which are related to areas like Mitochondrial permeability transition pore. The Lipid peroxidation research Alberto Bindoli does as part of his general Antioxidant study is frequently linked to other disciplines of science, such as KEAP1, therefore creating a link between diverse domains of science. His Mitochondrion research is multidisciplinary, relying on both Glutathione, Glutaredoxin 2, Programmed cell death and Doxorubicin.
The scientist’s investigation covers issues in Biochemistry, Thioredoxin reductase, Antioxidant, Cytosol and Thioredoxin. He studies Biochemistry, focusing on Oxidative stress in particular. His study in Thioredoxin reductase is interdisciplinary in nature, drawing from both Viability assay, Caco-2 and Glutathione reductase.
His research in Antioxidant intersects with topics in Oxidative phosphorylation and Phenols. As a part of the same scientific family, Alberto Bindoli mostly works in the field of Cytosol, focusing on Mitochondrion and, on occasion, Apoptosis and Organelle membrane. His Ferredoxin-thioredoxin reductase study, which is part of a larger body of work in Thioredoxin, is frequently linked to Auranofin, bridging the gap between disciplines.
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Thioredoxin reductase: A target for gold compounds acting as potential anticancer drugs
Alberto Bindoli;Maria Pia Rigobello;Guido Scutari;Chiara Gabbiani.
Coordination Chemistry Reviews (2009)
The role of selenium peroxidases in the protection against oxidative damage of membranes
Fulvio Ursini;Alberto Bindoli.
Chemistry and Physics of Lipids (1987)
Inhibition of thioredoxin reductase by auranofin induces apoptosis in cisplatin-resistant human ovarian cancer cells.
Christine Marzano;Valentina Gandin;Alessandra Folda;Guido Scutari.
Free Radical Biology and Medicine (2007)
Biochemical and toxicological properties of the oxidation products of catecholamines
Alberto Bindoli;Maria Pia Rigobello;David J. Deeble.
Free Radical Biology and Medicine (1992)
Emerging protein targets for anticancer metallodrugs: inhibition of thioredoxin reductase and cathepsin B by antitumor ruthenium(II)-arene compounds
Angela Casini;Chiara Gabbiani;Francesca Sorrentino;Maria Pia Rigobello.
Journal of Medicinal Chemistry (2008)
Thiol chemistry in peroxidase catalysis and redox signaling.
Alberto Bindoli;Jon M. Fukuto;Henry Jay Forman.
Antioxidants & Redox Signaling (2008)
Cancer cell death induced by phosphine gold(I) compounds targeting thioredoxin reductase.
Valentina Gandin;Aristi Potamitou Fernandes;Maria Pia Rigobello;Barbara Dani.
Biochemical Pharmacology (2010)
Lipid peroxidation in mitochondria
Free Radical Biology and Medicine (1988)
Induction of mitochondrial permeability transition by auranofin, a Gold(I)‐phosphine derivative
Maria Pia Rigobello;Guido Scutari;Rita Boscolo;Alberto Bindoli.
British Journal of Pharmacology (2002)
Gold complexes inhibit mitochondrial thioredoxin reductase: consequences on mitochondrial functions
Maria Pia Rigobello;Luigi Messori;Giordana Marcon;Maria Agostina Cinellu.
Journal of Inorganic Biochemistry (2004)
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