D-Index & Metrics Best Publications

D-Index & Metrics D-index (Discipline H-index) only includes papers and citation values for an examined discipline in contrast to General H-index which accounts for publications across all disciplines.

Discipline name D-index D-index (Discipline H-index) only includes papers and citation values for an examined discipline in contrast to General H-index which accounts for publications across all disciplines. Citations Publications World Ranking National Ranking
Biology and Biochemistry D-index 40 Citations 7,138 87 World Ranking 17058 National Ranking 482

Overview

What is he best known for?

The fields of study he is best known for:

  • Enzyme
  • Biochemistry
  • Amino acid

His primary areas of investigation include Biochemistry, Thioredoxin reductase, Thioredoxin, Auranofin and Glutathione. His work on Enzyme, Peroxidase and Mitochondrion as part of general Biochemistry study is frequently linked to Adrenochrome, therefore connecting diverse disciplines of science. The various areas that Alberto Bindoli examines in his Mitochondrion study include Malondialdehyde and Cytochrome P450.

Alberto Bindoli has included themes like Apoptosis, Stereochemistry, Cisplatin and Membrane permeability in his Thioredoxin reductase study. His Thioredoxin research incorporates elements of Thiol, Nicotinamide adenine dinucleotide phosphate, Inner mitochondrial membrane, Glutathione reductase and Cytosol. Glutathione and Lipid peroxidation are commonly linked in his work.

His most cited work include:

  • Thioredoxin reductase: A target for gold compounds acting as potential anticancer drugs (391 citations)
  • The role of selenium peroxidases in the protection against oxidative damage of membranes (322 citations)
  • Inhibition of thioredoxin reductase by auranofin induces apoptosis in cisplatin-resistant human ovarian cancer cells. (282 citations)

What are the main themes of his work throughout his whole career to date?

His primary scientific interests are in Biochemistry, Thioredoxin reductase, Thioredoxin, Mitochondrion and Antioxidant. His study on Biochemistry is mostly dedicated to connecting different topics, such as Biophysics. His Thioredoxin reductase study combines topics from a wide range of disciplines, such as Stereochemistry and Glutathione reductase.

His Thioredoxin research includes themes of Reactive oxygen species, Cell biology, Redox and Peroxiredoxin. Alberto Bindoli combines subjects such as ATP synthase, Membrane potential and Mitochondrial permeability transition pore with his study of Mitochondrion. His work on Lipid peroxidation and Butylated hydroxytoluene as part of general Antioxidant research is frequently linked to KEAP1, bridging the gap between disciplines.

He most often published in these fields:

  • Biochemistry (64.00%)
  • Thioredoxin reductase (33.60%)
  • Thioredoxin (28.00%)

What were the highlights of his more recent work (between 2015-2021)?

  • Biochemistry (64.00%)
  • Thioredoxin reductase (33.60%)
  • Thioredoxin (28.00%)

In recent papers he was focusing on the following fields of study:

Alberto Bindoli mostly deals with Biochemistry, Thioredoxin reductase, Thioredoxin, Antioxidant and Mitochondrion. His work on Cytosol and Gastrointestinal digestion as part of general Biochemistry study is frequently connected to Keap1 nrf2, therefore bridging the gap between diverse disciplines of science and establishing a new relationship between them. His Thioredoxin reductase research incorporates themes from Redox, Horseradish peroxidase and Glutathione reductase.

His work in Thioredoxin covers topics such as Peroxiredoxin which are related to areas like Mitochondrial permeability transition pore. The Lipid peroxidation research Alberto Bindoli does as part of his general Antioxidant study is frequently linked to other disciplines of science, such as KEAP1, therefore creating a link between diverse domains of science. His Mitochondrion research is multidisciplinary, relying on both Glutathione, Glutaredoxin 2, Programmed cell death and Doxorubicin.

Between 2015 and 2021, his most popular works were:

  • European contribution to the study of ROS : a summary of the findings and prospects for the future from the COST action BM1203 (EU-ROS) (132 citations)
  • Significance of the mitochondrial thioredoxin reductase in cancer cells: An update on role, targets and inhibitors. (38 citations)
  • Mitochondrial Thioredoxin System as a Modulator of Cyclophilin D Redox State (27 citations)

In his most recent research, the most cited papers focused on:

  • Enzyme
  • Amino acid
  • Biochemistry

The scientist’s investigation covers issues in Biochemistry, Thioredoxin reductase, Antioxidant, Cytosol and Thioredoxin. He studies Biochemistry, focusing on Oxidative stress in particular. His study in Thioredoxin reductase is interdisciplinary in nature, drawing from both Viability assay, Caco-2 and Glutathione reductase.

His research in Antioxidant intersects with topics in Oxidative phosphorylation and Phenols. As a part of the same scientific family, Alberto Bindoli mostly works in the field of Cytosol, focusing on Mitochondrion and, on occasion, Apoptosis and Organelle membrane. His Ferredoxin-thioredoxin reductase study, which is part of a larger body of work in Thioredoxin, is frequently linked to Auranofin, bridging the gap between disciplines.

This overview was generated by a machine learning system which analysed the scientist’s body of work. If you have any feedback, you can contact us here.

Best Publications

Thioredoxin reductase: A target for gold compounds acting as potential anticancer drugs

Alberto Bindoli;Maria Pia Rigobello;Guido Scutari;Chiara Gabbiani.
Coordination Chemistry Reviews (2009)

521 Citations

The role of selenium peroxidases in the protection against oxidative damage of membranes

Fulvio Ursini;Alberto Bindoli.
Chemistry and Physics of Lipids (1987)

476 Citations

Inhibition of thioredoxin reductase by auranofin induces apoptosis in cisplatin-resistant human ovarian cancer cells.

Christine Marzano;Valentina Gandin;Alessandra Folda;Guido Scutari.
Free Radical Biology and Medicine (2007)

376 Citations

Biochemical and toxicological properties of the oxidation products of catecholamines

Alberto Bindoli;Maria Pia Rigobello;David J. Deeble.
Free Radical Biology and Medicine (1992)

339 Citations

Emerging protein targets for anticancer metallodrugs: inhibition of thioredoxin reductase and cathepsin B by antitumor ruthenium(II)-arene compounds

Angela Casini;Chiara Gabbiani;Francesca Sorrentino;Maria Pia Rigobello.
Journal of Medicinal Chemistry (2008)

298 Citations

Thiol chemistry in peroxidase catalysis and redox signaling.

Alberto Bindoli;Jon M. Fukuto;Henry Jay Forman.
Antioxidants & Redox Signaling (2008)

276 Citations

Cancer cell death induced by phosphine gold(I) compounds targeting thioredoxin reductase.

Valentina Gandin;Aristi Potamitou Fernandes;Maria Pia Rigobello;Barbara Dani.
Biochemical Pharmacology (2010)

255 Citations

Lipid peroxidation in mitochondria

Alberto Bindoli.
Free Radical Biology and Medicine (1988)

240 Citations

Induction of mitochondrial permeability transition by auranofin, a Gold(I)‐phosphine derivative

Maria Pia Rigobello;Guido Scutari;Rita Boscolo;Alberto Bindoli.
British Journal of Pharmacology (2002)

206 Citations

Gold complexes inhibit mitochondrial thioredoxin reductase: consequences on mitochondrial functions

Maria Pia Rigobello;Luigi Messori;Giordana Marcon;Maria Agostina Cinellu.
Journal of Inorganic Biochemistry (2004)

205 Citations

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