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Chemistry

D-Index
65
Citations
15516
World Ranking
7643
National Ranking
548

Overview

Ingo Ott is affiliated with Technische Universität Braunschweig in Germany and has a research focus primarily within the fields of materials science and chemistry. Their work spans multiple subfields, including materials chemistry, organic chemistry, oncology, molecular biology, and inorganic chemistry. The scientific contributions of Ingo Ott are reflected in publications distributed across several well-known venues.

Their frequent publication venues include: The Cambridge Structural Database with 47 publications, Journal of Medicinal Chemistry with 4 publications, Chemistry - A European Journal with 3 publications, RSC Medicinal Chemistry with 3 publications, and International Journal of Molecular Sciences also with 3 publications.

Research topics explored by Ingo Ott cover a range of areas:

  • Crystallization and Solubility Studies
  • X-ray Diffraction in Crystallography
  • Metal complexes synthesis and properties
  • N-Heterocyclic Carbenes in Organic and Inorganic Chemistry
  • Ferrocene Chemistry and Applications
  • Organometallic Complex Synthesis and Catalysis
  • Click Chemistry and Applications

Ingo Ott has frequently collaborated with several co-authors including Petra Lippmann (34 joint publications), Uttara Basu (24 publications), Rolf Büssing (19 publications), Mark Brönstrup (17 publications), and Bianka Karge (16 publications).

Among their recent scientific papers are:

  • "Gold Metallodrugs to Target Coronavirus Proteins: Inhibitory Effects on the Spike-ACE2 Interaction and on PLpro Protease Activity by Auranofin and Gold Organometallics," 2020, Chemistry - A European Journal
  • "Potent Inhibition of Thioredoxin Reductase by the Rh Derivatives of Anticancer M(arene/Cp*)(NHC)Cl2Complexes," 2020, Inorganic Chemistry
  • "A Multitarget Gold(I) Complex Induces Cytotoxicity Related to Aneuploidy in HCT-116 Colorectal Carcinoma Cells," 2020, Angewandte Chemie International Edition
  • "Metallodrug Profiling against SARS-CoV-2 Target Proteins Identifies Highly Potent Inhibitors of the S/ACE2 interaction and the Papain-like Protease PLpro," 2021, Chemistry - A European Journal
  • "Gold(I) and Gold(III) N-Heterocyclic Carbene Complexes as Antibacterial Agents and Inhibitors of Bacterial Thioredoxin Reductase," 2021, ChemMedChem

Best Publications

  • Organometallic Anticancer Compounds

    Gilles Gasser;Gilles Gasser;Ingo Ott;Nils Metzler-Nolte

  • On the medicinal chemistry of gold complexes as anticancer drugs

    Ingo Ott

  • Non platinum metal complexes as anti-cancer drugs.

    Ingo Ott;Ronald Gust

  • N-Heterocyclic carbene metal complexes in medicinal chemistry

    Luciano Oehninger;Riccardo Rubbiani;Ingo Ott

  • Benzimidazol-2-ylidene Gold(I) Complexes Are Thioredoxin Reductase Inhibitors with Multiple Antitumor Properties

    Riccardo Rubbiani;Igor Kitanovic;Hamed Alborzinia;Suzan Can

  • Cellular uptake, cytotoxicity, and metabolic profiling of human cancer cells treated with ruthenium(II) polypyridyl complexes [Ru(bpy)2(N--N)]Cl2 with N--N=bpy, phen, dpq, dppz, and dppn.

    Ulrich Schatzschneider;Johanna Niesel;Ingo Ott;Ronald Gust

  • Molecular and Cellular Characterization of the Biological Effects of Ruthenium(II) Complexes Incorporating 2-Pyridyl-2-pyrimidine-4-carboxylic Acid

    Vanessa Pierroz;Tanmaya Joshi;Anna Leonidova;Cristina Mari

  • Comparative in Vitro Evaluation of N-Heterocyclic Carbene Gold(I) Complexes of the Benzimidazolylidene Type

    Riccardo Rubbiani;Suzan Can;Igor Kitanovic;Hamed Alborzinia

  • Antitumor-active cobalt-alkyne complexes derived from acetylsalicylic acid: studies on the mode of drug action.

    Ingo Ott;Kathrin Schmidt;Brigitte Kircher;Petra Schumacher

  • Photoinduced CO release, cellular uptake and cytotoxicity of a tris(pyrazolyl)methane (tpm) manganese tricarbonyl complex

    Johanna Niesel;Antonio Pinto;Harmel W. Peindy N'Dongo;Klaus Merz

  • Influence of the Polypyridyl (pp) Ligand Size on the DNA Binding Properties, Cytotoxicity and Cellular Uptake of Organoruthenium(II) Complexes of the Type [(η6-C6Me6)Ru(L)(pp)]n+ [L = Cl, n = 1; L = (NH2)2CS, n = 2]

    Sven Schäfer;Ingo Ott;Ronald Gust;William S. Sheldrick

  • A gold(I) phosphine complex containing a naphthalimide ligand functions as a TrxR inhibiting antiproliferative agent and angiogenesis inhibitor.

    Ingo Ott;Xuhong Qian;Yufang Xu;Danielle H. W. Vlecken

  • DNA intercalating Ru(II) polypyridyl complexes as effective photosensitizers in photodynamic therapy.

    Cristina Mari;Vanessa Pierroz;Riccardo Rubbiani;Malay Patra

  • Gold(I) NHC Complexes: Antiproliferative Activity, Cellular Uptake, Inhibition of Mammalian and Bacterial Thioredoxin Reductases, and Gram‐Positive Directed Antibacterial Effects

    Claudia Schmidt;Bianka Karge;Rainer Misgeld;Aram Prokop

  • On the biological properties of alkynyl phosphine gold(I) complexes.

    Andreas Meyer;Christoph P. Bagowski;Malte Kokoschka;Maria Stefanopoulou

  • Analysis of the mechanism of action of potent antibacterial hetero-tri-organometallic compounds: a structurally new class of antibiotics.

    Michaela Wenzel;Malay Patra;Christoph Helmut Rudi Senges;Ingo Ott

  • Development of cobalt(3,4-diarylsalen) complexes as tumor therapeutics.

    Ronald Gust;Ingo Ott;Diana Posselt;Klaus Sommer

  • Evaluation of arene ruthenium(II) N-heterocyclic carbene complexes as organometallics interacting with thiol and selenol containing biomolecules

    Luciano Oehninger;Maria Stefanopoulou;Hamed Alborzinia;Julia Schur

  • A spontaneous gold(I)-azide alkyne cycloaddition reaction yields gold-peptide bioconjugates which overcome cisplatin resistance in a p53-mutant cancer cell line

    S. David Köster;Hamed Alborzinia;Suzan Can;Igor Kitanovic

  • Modulation of the Biological Properties of Aspirin by Formation of a Bioorganometallic Derivative

    Ingo Ott;Brigitte Kircher;Christoph P. Bagowski;Danielle H. W. Vlecken

  • Non Platinum Metal Complexes as Anticancer Drugs

    Ingo Ott;Ronald Gust

Frequent Co-Authors

Ronald Gust
Ronald Gust Freie Universität Berlin
William S. Sheldrick
William S. Sheldrick Ruhr University Bochum
Nils Metzler-Nolte
Nils Metzler-Nolte Ruhr University Bochum
Angela Casini
Angela Casini Technical University of Munich
Gilles Gasser
Gilles Gasser Chimie ParisTech
Bruno Therrien
Bruno Therrien University of Neuchâtel
Bernhard K. Keppler
Bernhard K. Keppler University of Vienna
Klaus Wurst
Klaus Wurst University of Innsbruck
Xuhong Qian
Xuhong Qian East China University of Science and Technology
Viktor Brabec
Viktor Brabec Czech Academy of Sciences

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