What is he best known for?
The fields of study he is best known for:
- Organic chemistry
- Enzyme
- Gene
Ruthenium, Stereochemistry, Cisplatin, Ligand and Platinum are his primary areas of study.
His Ruthenium research incorporates elements of Indazole, Medicinal chemistry and Metal.
Particularly relevant to Nuclear magnetic resonance spectroscopy is his body of work in Stereochemistry.
His Cisplatin study combines topics in areas such as Cancer, Cancer chemotherapy, Cancer research, Oxaliplatin and Pharmacology.
The various areas that Bernhard K. Keppler examines in his Ligand study include Biological activity, Lipophilicity, Reactivity and Aquation.
Bernhard K. Keppler has researched Platinum in several fields, including Inductively coupled plasma mass spectrometry, Prodrug and Chromatography, Capillary electrophoresis.
His most cited work include:
- From bench to bedside – preclinical and early clinical development of the anticancer agent indazolium trans-[tetrachlorobis(1H-indazole)ruthenate(III)] (KP1019 or FFC14A) (728 citations)
- Antitumour metal compounds: more than theme and variations. (655 citations)
- KP1019, a new redox-active anticancer agent--preclinical development and results of a clinical phase I study in tumor patients. (532 citations)
What are the main themes of his work throughout his whole career to date?
The scientist’s investigation covers issues in Stereochemistry, Ruthenium, Platinum, Medicinal chemistry and Ligand.
His Stereochemistry study incorporates themes from In vitro, Cytotoxicity and Cisplatin.
His study in Cisplatin is interdisciplinary in nature, drawing from both Cancer research, Oxaliplatin and Pharmacology.
The Ruthenium study which covers Indazole that intersects with Imidazole.
Bernhard K. Keppler focuses mostly in the field of Platinum, narrowing it down to topics relating to Chromatography and, in certain cases, Blood proteins.
The concepts of his Medicinal chemistry study are interwoven with issues in Organic chemistry and Crystal structure.
He most often published in these fields:
- Stereochemistry (31.26%)
- Ruthenium (20.66%)
- Platinum (15.10%)
What were the highlights of his more recent work (between 2016-2021)?
- Ligand (12.32%)
- In vivo (9.93%)
- Stereochemistry (31.26%)
In recent papers he was focusing on the following fields of study:
Bernhard K. Keppler mostly deals with Ligand, In vivo, Stereochemistry, Ruthenium and Aqueous solution.
Within one scientific family, Bernhard K. Keppler focuses on topics pertaining to Cytotoxicity under Ligand, and may sometimes address concerns connected to Nuclear magnetic resonance spectroscopy.
His research integrates issues of Sample preparation, Biochemistry, Serum albumin and Pharmacology in his study of In vivo.
His studies in Stereochemistry integrate themes in fields like DNA, Cytotoxic T cell and Medicinal chemistry.
His Ruthenium study which covers Combinatorial chemistry that intersects with Prodrug.
His Aqueous solution research is multidisciplinary, incorporating elements of Nuclear chemistry, Inorganic chemistry, Leaching, Ionic liquid and Metal.
Between 2016 and 2021, his most popular works were:
- Structure–activity relationships for ruthenium and osmium anticancer agents – towards clinical development (153 citations)
- Metal Drugs and the Anticancer Immune Response. (75 citations)
- Metal Drugs and the Anticancer Immune Response. (75 citations)
In his most recent research, the most cited papers focused on:
- Organic chemistry
- Enzyme
- Gene
His main research concerns In vivo, Ruthenium, Stereochemistry, DNA and Platinum.
His In vivo research is multidisciplinary, relying on both Transferrin, Serum albumin, Cisplatin and Chloride.
His Ruthenium research includes elements of Moiety, Metal and Molecular targets.
In his study, which falls under the umbrella issue of Stereochemistry, Redox, Lipophilicity, Cytotoxic T cell and Ic50 values is strongly linked to Ligand.
His research integrates issues of Nuclear chemistry, Coordination sphere, Oxaliplatin, Prodrug and Nuclear magnetic resonance spectroscopy in his study of Platinum.
His Oxaliplatin research is multidisciplinary, incorporating elements of In vitro, Cytotoxicity, Reactivity, Flow cytometry and Pharmacology.
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