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Chemistry
Italy
2025

D-Index & Metrics

Chemistry

D-Index
70
Citations
15416
World Ranking
5955
National Ranking
129

Research.com Recognitions

  • 2025 - Research.com Chemistry in Italy Leader Award
  • 2022 - Research.com Chemistry in Italy Leader Award

Overview

Enzo Alessio is affiliated with the University of Trieste in Italy and has a research focus intersecting materials science and chemistry. Their scholarly work primarily covers topics within materials chemistry and organic and inorganic chemistry, reflecting an interdisciplinary approach to molecular and structural studies.

The scientist's publication record includes contributions to both journals and collaborative research efforts in several specialized fields. Alessio's research spans the chemistry of metal complexes, crystallization and solubility studies, and the analysis of molecular interactions through crystallography techniques.

Among their notable recent papers are:

  • A Maltol-Containing Ruthenium Polypyridyl Complex as a Potential Anticancer Agent (2020), Chemistry - A European Journal
  • Pd-Catalyzed CO/Vinyl Arene Copolymerization: when the Stereochemistry is Controlled by the Comonomer (2020), Macromolecules
  • Ruthenium(II) Polypyridyl Complexes Containing Simple Dioxo Ligands: a Structure-Activity Relationship Study Shows the Importance of the Charge (2022), ChemBioChem
  • cis-Locked Ru(II)-DMSO Precursors for the Microwave-Assisted Synthesis of Bis-Heteroleptic Polypyridyl Compounds (2021), Inorganic Chemistry
  • Models of molecular photocatalysts for water oxidation: Strategies for conjugating the Ru(bda) fragment (bda = 2,2'-bipyridine-6,6'-dicarboxylate) to porphyrin photosensitizers (2020), Inorganica Chimica Acta

Alessio frequently publishes in venues including:

  • The Cambridge Structural Database
  • Inorganic Chemistry
  • Chemistry - A European Journal
  • Macromolecules
  • ChemBioChem

Their collaborations feature recurring co-authors with whom Alessio has published multiple times. These include Gabriele Balducci, Alessio Vidal, Federica Battistin, Elisabetta Iengo, and Bárbara Milani.

The scientist's main research topics are varied and include:

  • Crystallization and Solubility Studies
  • X-ray Diffraction in Crystallography
  • Metal complexes synthesis and properties
  • Porphyrin and Phthalocyanine Chemistry
  • Metal-Catalyzed Oxygenation Mechanisms
  • Organometallic Complex Synthesis and Catalysis
  • Crystallography and molecular interactions

Best Publications

  • Ruthenium Antimetastatic Agents

    Enzo Alessio;Giovanni Mestroni;Alberta Bergamo;Gianni Sava

  • Second-order moving average and scaling of stochastic time series

    E. Alessio;Anna Filomena Carbone;G. Castelli;V. Frappietro

  • Phase I/II study with ruthenium compound NAMI-A and gemcitabine in patients with non-small cell lung cancer after first line therapy

    Suzanne Leijen;Sjaak A. Burgers;Paul Baas;Dick Pluim

  • cis- and trans-dihalotetrakis(dimethyl sulfoxide)ruthenium(II) complexes (RuX2(DMSO)4; X=Cl, Br): synthesis, structure, and antitumor activity

    Enzo Alessio;Giovanni Mestroni;Giorgio Nardin;Wahib M. Attia

  • NAMI-A and KP1019/1339, Two Iconic Ruthenium Anticancer Drug Candidates Face-to-Face: A Case Story in Medicinal Inorganic Chemistry

    Enzo Alessio;Luigi Messori

  • Thirty Years of the Drug Candidate NAMI‐A and the Myths in the Field of Ruthenium Anticancer Compounds: A Personal Perspective

    Enzo Alessio

  • Trinuclear metallacycles: metallatriangles and much more.

    Ennio Zangrando;Massimo Casanova;Enzo Alessio

  • Influence of chemical stability on the activity of the antimetastasis ruthenium compound NAMI-A

    G Sava;A Bergamo;S Zorzet;B Gava

  • A categorization of metal anticancer compounds based on their mode of action.

    Teresa Gianferrara;Ioannis Bratsos;Enzo Alessio

  • Ruthenium Anticancer Compounds: Challenges and Expectations

    Ioannis Bratsos;Stephanie Jedner;Teresa Gianferrara;Enzo Alessio

  • Synthesis and reactivity of Ru-, Os-, Rh-, and Ir-halide-sulfoxide complexes.

    Enzo Alessio

  • Bioinorganic medicinal chemistry

    Enzo Alessio

  • Synthesis, molecular structure, and chemical behavior of hydrogen trans-bis(dimethyl sulfoxide)tetrachlororuthenate(III) and mer-trichlorotris(dimethyl sulfoxide)ruthenium(III): the first fully characterized chloride-dimethyl sulfoxide-ruthenium(III) complexes

    Enzo. Alessio;Gabriele. Balducci;Mario. Calligaris;Giacomo. Costa

  • PHARMACOLOGICAL CONTROL OF LUNG METASTASES OF SOLID TUMOURS BY A NOVEL RUTHENIUM COMPLEX

    G. Sava;I. Capozzi;K. Clerici;G. Gagliardi

  • In vitro cell cycle arrest, in vivo action on solid metastasizing tumors, and host toxicity of the antimetastatic drug NAMI-A and cisplatin.

    A Bergamo;R Gagliardi;V Scarcia;A Furlani

  • Synthesis and characterization of two new classes of ruthenium(III)-sulfoxide complexes with nitrogen donor ligands (L): Na[trans-RuCl4(R2SO)(L)] and mer, cis-RuCl3(R2SO)(R2SO)(L). The crystal structure of Na[trans-RuCl4(DMSO)(NH3)] · 2DMSO, Na[trans-RuCl4(DMSO)(Im)] · H2O, Me2CO (Im = imidazole) and mer, cis-RuCl3(DMSO)(DMSO)(NH3)

    Enzo Alessio;Gabriele Balducci;A. Lutman;Giovanni Mestroni

  • The hydrolysis of the anti-cancer ruthenium complex NAMI-A affects its DNA binding and antimetastatic activity: an NMR evaluation.

    Marina Bacac;Anna C.G Hotze;Karlijn van der Schilden;Jaap G Haasnoot

  • Wavelength-dependent electron and energy transfer pathways in a side-to-face ruthenium porphyrin/perylene bisimide assembly.

    Anna Prodi;Claudio Chiorboli;Franco Scandola;Elisabetta Iengo

  • Water-Soluble Ruthenium(III)-Dimethyl Sulfoxide Complexes: Chemical Behaviour and Pharmaceutical Properties.

    G. Mestroni;E. Alessio;G. Sava;S. Pacor

  • Chemistry and reactivity of ruthenium(II) complexes: DNA/protein binding mode and anticancer activity are related to the complex structure

    Ana Rilak Simović;Romana Masnikosa;Ioannis Bratsos;Enzo Alessio

  • A spectroscopic study of the reaction of NAMI, a novel ruthenium(III)anti-neoplastic complex, with bovine serum albumin.

    Luigi Messori;Pierluigi Orioli;Daniela Vullo;Enzo Alessio

Frequent Co-Authors

Giovanni Mestroni
Giovanni Mestroni University of Trieste
Gianni Sava
Gianni Sava University of Trieste
Ennio Zangrando
Ennio Zangrando University of Trieste
Luigi G. Marzilli
Luigi G. Marzilli Louisiana State University
Franco Scandola
Franco Scandola University of Ferrara
Silvano Geremia
Silvano Geremia University of Trieste
Luigi Messori
Luigi Messori University of Florence
Iztok Turel
Iztok Turel University of Ljubljana
Franco Quadrifoglio
Franco Quadrifoglio University of Udine
Maurizio Prato
Maurizio Prato University of Trieste

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