His primary scientific interests are in NAMI-A, Ruthenium, Stereochemistry, Medicinal chemistry and Organic chemistry. He has included themes like Cancer research, Antimetastatic Agent, Metastasis, Pathology and Cytotoxicity in his NAMI-A study. His Ruthenium research is multidisciplinary, incorporating elements of Combinatorial chemistry and Dimethyl sulfoxide.
His Stereochemistry study incorporates themes from Sulfoxide, Macromolecule, Ligand and Crystal structure. His research investigates the connection between Organic chemistry and topics such as Polymer chemistry that intersect with problems in Rhodium and Selective reduction. In general Catalysis, his work in Palladium, Hydrogen transfer and Transition metal is often linked to Homogeneous linking many areas of study.
Giovanni Mestroni spends much of his time researching Medicinal chemistry, Catalysis, Organic chemistry, Ruthenium and Stereochemistry. The concepts of his Medicinal chemistry study are interwoven with issues in Rhodium, Ligand, Cobalt, Molecule and Aryl. His biological study spans a wide range of topics, including Phenanthroline and Polymer chemistry.
His studies deal with areas such as Sulfoxide, Cancer research, Cisplatin, Dimethyl sulfoxide and Lewis lung carcinoma as well as Ruthenium. Giovanni Mestroni usually deals with Lewis lung carcinoma and limits it to topics linked to Pathology and NAMI-A. His Stereochemistry research is multidisciplinary, relying on both Pyridine, Isomerization and Crystal structure.
His scientific interests lie mostly in Ruthenium, Polymer chemistry, Palladium, Ligand and Polymerization. The NAMI-A research he does as part of his general Ruthenium study is frequently linked to other disciplines of science, such as Nitrogen oxide, therefore creating a link between diverse domains of science. His work deals with themes such as Nitric oxide and Nitrogen, which intersect with Polymer chemistry.
His study on Palladium also encompasses disciplines like
Giovanni Mestroni mainly investigates NAMI-A, Ruthenium, Lewis lung carcinoma, Pathology and Stereochemistry. His NAMI-A research integrates issues from Metastasis, Cisplatin and Cytotoxicity. His studies in Ruthenium integrate themes in fields like Sulfoxide, Dimethyl sulfoxide and Combinatorial chemistry.
Giovanni Mestroni focuses mostly in the field of Sulfoxide, narrowing it down to topics relating to Derivative and, in certain cases, Medicinal chemistry. His Lewis lung carcinoma study integrates concerns from other disciplines, such as Cell cycle and Cancer research. His research combines Isomerization and Stereochemistry.
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Asymmetric hydrogen transfer reactions promoted by homogeneous transition metal catalysts
Grazia Zassinovich;Giovanni Mestroni;Serafino Gladiali.
Chemical Reviews (1992)
Ruthenium Antimetastatic Agents
Enzo Alessio;Giovanni Mestroni;Alberta Bergamo;Gianni Sava.
Current Topics in Medicinal Chemistry (2004)
cis- and trans-dihalotetrakis(dimethyl sulfoxide)ruthenium(II) complexes (RuX2(DMSO)4; X=Cl, Br): synthesis, structure, and antitumor activity
Enzo Alessio;Giovanni Mestroni;Giorgio Nardin;Wahib M. Attia.
Inorganic Chemistry (1988)
Influence of chemical stability on the activity of the antimetastasis ruthenium compound NAMI-A
G Sava;A Bergamo;S Zorzet;B Gava.
European Journal of Cancer (2002)
Synthesis, molecular structure, and chemical behavior of hydrogen trans-bis(dimethyl sulfoxide)tetrachlororuthenate(III) and mer-trichlorotris(dimethyl sulfoxide)ruthenium(III): the first fully characterized chloride-dimethyl sulfoxide-ruthenium(III) complexes
Enzo. Alessio;Gabriele. Balducci;Mario. Calligaris;Giacomo. Costa.
Inorganic Chemistry (1991)
In vitro cell cycle arrest, in vivo action on solid metastasizing tumors, and host toxicity of the antimetastatic drug NAMI-A and cisplatin.
A Bergamo;R Gagliardi;V Scarcia;A Furlani.
Journal of Pharmacology and Experimental Therapeutics (1999)
Bis-Chelated Palladium(II) Complexes with Nitrogen-Donor Chelating Ligands Are Efficient Catalyst Precursors for the CO/Styrene Copolymerization Reaction
Barbara Milani;Anna Anzilutti;Lidia Vicentini;Andrea Sessanta o Santi.
PHARMACOLOGICAL CONTROL OF LUNG METASTASES OF SOLID TUMOURS BY A NOVEL RUTHENIUM COMPLEX
G. Sava;I. Capozzi;K. Clerici;G. Gagliardi.
Clinical & Experimental Metastasis (1998)
Synthesis and characterization of two new classes of ruthenium(III)-sulfoxide complexes with nitrogen donor ligands (L): Na[trans-RuCl4(R2SO)(L)] and mer, cis-RuCl3(R2SO)(R2SO)(L). The crystal structure of Na[trans-RuCl4(DMSO)(NH3)] · 2DMSO, Na[trans-RuCl4(DMSO)(Im)] · H2O, Me2CO (Im = imidazole) and mer, cis-RuCl3(DMSO)(DMSO)(NH3)
Enzo Alessio;Gabriele Balducci;A. Lutman;Giovanni Mestroni.
Inorganica Chimica Acta (1993)
Sulfoxide Ruthenium Complexes: Non-Toxic Tools for the Selective Treatment of Solid Tumour Metastases
Gianni Sava;Enzo Alessio;Alberta Bergamo;Giovanni Mestroni.
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