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Chemistry

D-Index
70
Citations
16908
World Ranking
5871
National Ranking
126

Overview

Gianni Sava is affiliated with the University of Trieste in Italy and has a research focus spanning medicine and biochemistry, genetics, and molecular biology. Their work covers several specialized subfields including surgery, hematology, endocrinology, molecular biology, and infectious diseases.

The scientist's recent publications highlight topics related to vaccination adverse events, muscle physiology, and antiviral natural products. Their work has appeared in multiple established journals, with some of the notable recent papers being:

  • "Blood clots and bleeding events following BNT162b2 and ChAdOx1 nCoV-19 vaccine: An analysis of European data" (2021), published in the Journal of Autoimmunity
  • "Cardiovascular, neurological, and pulmonary events following vaccination with the BNT162b2, ChAdOx1 nCoV-19, and Ad26.COV2.S vaccines: An analysis of European data" (2021), published in the Journal of Autoimmunity
  • "Age Dependent Modification of the Metabolic Profile of the Tibialis Anterior Muscle Fibers in C57BL/6J Mice" (2020), published in the International Journal of Molecular Sciences
  • "Lysozyme: A Natural Product with Multiple and Useful Antiviral Properties" (2024), published in Molecules
  • "Long-term resveratrol treatment improves the capillarization in the skeletal muscles of ageing C57BL/6J mice" (2020), published in the International Journal of Food Sciences and Nutrition

Gianni Sava has contributed to studies frequently published in venues such as the Journal of Autoimmunity, Molecules, International Journal of Molecular Sciences, International Journal of Food Sciences and Nutrition, and Frontiers in Cardiovascular Medicine.

Their main research topics include heparin-induced thrombocytopenia and thrombosis, platelet disorders and treatments, Escherichia coli research studies, muscle physiology and disorders, adipose tissue and metabolism, aquaculture disease management and microbiota, and blood groups and transfusion.

Frequent collaborations feature co-authors such as Alberta Bergamo, Luigi Cari, Mahdieh Naghavi Alhosseini, Giuseppe Nocentini, and Emiliana Giacomello, indicating a consistent interdisciplinary approach across biomedical research areas.

Best Publications

  • In Vitro and in Vivo Evaluation of Ruthenium(II)−Arene PTA Complexes

    Claudine Scolaro;Alberta Bergamo;Laura Brescacin;Riccarda Delfino

  • Metal-based antitumour drugs in the post genomic era.

    Paul J Dyson;Gianni Sava

  • Approaching tumour therapy beyond platinum drugs : status of the art and perspectives of ruthenium drug candidates.

    A. Bergamo;C. Gaiddon;J.H.M. Schellens;J.H. Beijnen

  • Ruthenium Antimetastatic Agents

    Enzo Alessio;Giovanni Mestroni;Alberta Bergamo;Gianni Sava

  • A review on usnic acid, an interesting natural compound.

    Moreno Cocchietto;Nicola Skert;Pier Luigi Nimis;Gianni Sava

  • Ruthenium anticancer compounds: myths and realities of the emerging metal-based drugs.

    Alberta Bergamo;Gianni Sava

  • Phase I/II study with ruthenium compound NAMI-A and gemcitabine in patients with non-small cell lung cancer after first line therapy

    Suzanne Leijen;Sjaak A. Burgers;Paul Baas;Dick Pluim

  • cis- and trans-dihalotetrakis(dimethyl sulfoxide)ruthenium(II) complexes (RuX2(DMSO)4; X=Cl, Br): synthesis, structure, and antitumor activity

    Enzo Alessio;Giovanni Mestroni;Giorgio Nardin;Wahib M. Attia

  • Organometallic ruthenium-based antitumor compounds with novel modes of action

    Wee Han Ang;Angela Casini;Gianni Sava;Paul J. Dyson

  • Dual Action of NAMI-A in Inhibition of Solid Tumor Metastasis Selective Targeting of Metastatic Cells and Binding to Collagen

    Gianni Sava;Sonia Zorzet;Claudia Turrin;Francesca Vita

  • Influence of chemical stability on the activity of the antimetastasis ruthenium compound NAMI-A

    G Sava;A Bergamo;S Zorzet;B Gava

  • Modulation of the metastatic progression of breast cancer with an organometallic ruthenium compound.

    Alberta Bergamo;Alessia Masi;Paul J Dyson;Gianni Sava

  • Metal-based antitumour drugs in the post-genomic era: what comes next?

    Gianni Sava;Alberta Bergamo;Paul J. Dyson

  • PHARMACOLOGICAL CONTROL OF LUNG METASTASES OF SOLID TUMOURS BY A NOVEL RUTHENIUM COMPLEX

    G. Sava;I. Capozzi;K. Clerici;G. Gagliardi

  • In vitro cell cycle arrest, in vivo action on solid metastasizing tumors, and host toxicity of the antimetastatic drug NAMI-A and cisplatin.

    A Bergamo;R Gagliardi;V Scarcia;A Furlani

  • Linking the future of anticancer metal-complexes to the therapy of tumour metastases

    Alberta Bergamo;Gianni Sava

  • Development of ruthenium antitumor drugs that overcome multidrug resistance mechanisms.

    Carsten A. Vock;Wee Han Ang;Claudine Scolaro;Andrew D. Phillips

  • The hydrolysis of the anti-cancer ruthenium complex NAMI-A affects its DNA binding and antimetastatic activity: an NMR evaluation.

    Marina Bacac;Anna C.G Hotze;Karlijn van der Schilden;Jaap G Haasnoot

  • In vivo tumour and metastasis reduction and in vitro effects on invasion assays of the ruthenium RM175 and osmium AFAP51 organometallics in the mammary cancer model

    A. Bergamo;A. Masi;Anna F. A. Peacock;Abraha Habtemariam

  • Water-Soluble Ruthenium(III)-Dimethyl Sulfoxide Complexes: Chemical Behaviour and Pharmaceutical Properties.

    G. Mestroni;E. Alessio;G. Sava;S. Pacor

  • Synthesis, catalytic properties and biological activity of new water soluble ruthenium cyclopentadienyl PTA complexes [(C5R5)RuCl(PTA)2] (R = H, Me; PTA = 1,3,5-triaza-7-phosphaadamantane).

    Dina N. Akbayeva;Luca Gonsalvi;Werner Oberhauser;Maurizio Peruzzini

Frequent Co-Authors

Enzo Alessio
Enzo Alessio University of Trieste
Giovanni Mestroni
Giovanni Mestroni University of Trieste
Paul J. Dyson
Paul J. Dyson École Polytechnique Fédérale de Lausanne
Jos H. Beijnen
Jos H. Beijnen Utrecht University
Bernhard K. Keppler
Bernhard K. Keppler University of Vienna
Ennio Zangrando
Ennio Zangrando University of Trieste
Maurizio Prato
Maurizio Prato University of Trieste
Luigi Messori
Luigi Messori University of Florence
Spiridione Garbisa
Spiridione Garbisa University of Padua
Jan H.M. Schellens
Jan H.M. Schellens Utrecht University

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