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Biology and Biochemistry

D-Index
86
Citations
23203
World Ranking
3024
National Ranking
20

Overview

Walter Berger is affiliated with the Medical University of Vienna in Austria. Their research primarily spans the fields of Medicine and Biochemistry, Genetics, and Molecular Biology, with a focus on subfields such as Molecular Biology, Oncology, Pulmonary and Respiratory Medicine, Genetics, and Organic Chemistry.

The scientist's recent publications reflect a diverse interest in cancer research, metal complexes, and molecular mechanisms linked to oncology. Notable recent papers include:

  • Single-Cell RNA-Seq Reveals Cellular Hierarchies and Impaired Developmental Trajectories in Pediatric Ependymoma (2020, Cancer Cell)
  • Interaction with Ribosomal Proteins Accompanies Stress Induction of the Anticancer Metallodrug BOLD-100/KP1339 in the Endoplasmic Reticulum (2020, Angewandte Chemie International Edition)
  • Structure-Activity Relationships of Triple-Action Platinum(IV) Prodrugs with Albumin-Binding Properties and Immunomodulating Ligands (2021, Journal of Medicinal Chemistry)
  • Cancer Cell Resistance Against the Clinically Investigated Thiosemicarbazone COTI-2 Is Based on Formation of Intracellular Copper Complex Glutathione Adducts and ABCC1-Mediated Efflux (2020, Journal of Medicinal Chemistry)
  • A platinum(IV) prodrug strategy to overcome glutathione-based oxaliplatin resistance (2022, Communications Chemistry)

Walter Berger's work covers several main research topics including:

  • Glioma Diagnosis and Treatment
  • Metal complexes synthesis and properties
  • Occupational and environmental lung diseases
  • Cancer Research and Treatments
  • Cancer therapeutics and mechanisms
  • Neuroblastoma Research and Treatments
  • RNA modifications and cancer

The scientist has frequently published in venues such as:

  • Neuro-Oncology
  • Cancer Research
  • Inorganic Chemistry Frontiers
  • Cancers
  • Angewandte Chemie International Edition

Notable frequent coauthors in Walter Berger's collaborations include:

  • Christine Pirker
  • Johannes Gojo
  • Bernhard K. Keppler
  • Petra Heffeter
  • Dominik Kirchhofer

Best Publications

  • KP1019, a new redox-active anticancer agent--preclinical development and results of a clinical phase I study in tumor patients.

    Christian G. Hartinger;Christian G. Hartinger;Michael A. Jakupec;Stefanie Zorbas‐Seifried;Michael Groessl

  • New Brain Tumor Entities Emerge from Molecular Classification of CNS-PNETs

    Dominik Sturm;Dominik Sturm;Brent A. Orr;Umut H. Toprak;Volker Hovestadt

  • NKP-1339, the first ruthenium-based anticancer drug on the edge to clinical application

    Robert Trondl;Petra Heffeter;Christian R. Kowol;Michael A. Jakupec

  • Anticancer activity of metal complexes: involvement of redox processes.

    Ute Jungwirth;Christian R. Kowol;Bernhard K. Keppler;Christian G. Hartinger

  • Structure–activity relationships for ruthenium and osmium anticancer agents – towards clinical development

    Samuel M. Meier-Menches;Samuel M. Meier-Menches;Christopher Gerner;Walter Berger;Walter Berger;Christian G. Hartinger

  • Green tea extract and (–)-epigallocatechin-3-gallate, the major tea catechin, exert oxidant but lack antioxidant activities

    Leonilla Elbling;Rosa-Maria Weiss;Olga Teufelhofer;Maria Uhl

  • Metal Drugs and the Anticancer Immune Response.

    Bernhard Englinger;Christine Pirker;Petra Heffeter;Alessio Terenzi;Alessio Terenzi

  • Resistance against novel anticancer metal compounds: differences and similarities

    Petra Heffeter;Ute Jungwirth;Michael Jakupec;Christian Hartinger

  • Vaults and the major vault protein: Novel roles in signal pathway regulation and immunity

    W. Berger;E. Steiner;M. Grusch;L. Elbling

  • Heterocyclic complexes of ruthenium(III) induce apoptosis in colorectal carcinoma cells

    S. Kapitza;M. Pongratz;M. A. Jakupec;P. Heffeter

  • Spatio‐temporally precise activation of engineered receptor tyrosine kinases by light

    Michael Grusch;Karin Schelch;Robert Riedler;Eva Reichhart

  • Intracellular protein binding patterns of the anticancer ruthenium drugs KP1019 and KP1339

    Petra Heffeter;Katharina Böck;Bihter Atil;Mir Ali Reza Hoda

  • Impact of metal coordination on cytotoxicity of 3-aminopyridine-2-carboxaldehyde thiosemicarbazone (triapine) and novel insights into terminal dimethylation

    Christian R. Kowol;Robert Trondl;Petra Heffeter;Vladimir B. Arion

  • Multidrug resistance markers P-glycoprotein, multidrug resistance protein 1, and lung resistance protein in non-small cell lung cancer: prognostic implications

    Walter Berger;Ulrike Setinek;Peter Hollaus;Thomas Zidek

  • Podoplanin expression in primary brain tumors induces platelet aggregation and increases risk of venous thromboembolism.

    Julia Riedl;Matthias Preusser;Pegah Mir Seyed Nazari;Florian Posch;Florian Posch

  • Anticancer activity of the lanthanum compound [tris(1,10-phenanthroline)lanthanum(III)]trithiocyanate (KP772; FFC24).

    Petra Heffeter;Michael A. Jakupec;Wilfried Körner;Stefan Wild

  • Ophiobolin A induces paraptosis-like cell death in human glioblastoma cells by decreasing BKCa channel activity.

    M Bury;A Girault;Mégalizzi;S Spiegl-Kreinecker

  • Structure-activity relationship analysis of novel derivatives of narciclasine (an Amaryllidaceae isocarbostyril derivative) as potential anticancer agents.

    Laurent Ingrassia;Florence Lefranc;Janique Dewelle;Laurent Pottier

  • Uncertainty-aware exploration of continuous parameter spaces using multivariate prediction

    W. Berger;H. Piringer;P. Filzmoser;E. Gröller

  • Organometallic anticancer complexes of lapachol: metal centre-dependent formation of reactive oxygen species and correlation with cytotoxicity

    Wolfgang Kandioller;Evelyn Balsano;Samuel M Meier;Ute Jungwirth

Frequent Co-Authors

Bernhard K. Keppler
Bernhard K. Keppler University of Vienna
Michael A. Jakupec
Michael A. Jakupec University of Vienna
Walter Klepetko
Walter Klepetko Medical University of Vienna
Robert Kiss
Robert Kiss Université Libre de Bruxelles
Gunda Koellensperger
Gunda Koellensperger University of Vienna
Christian G. Hartinger
Christian G. Hartinger University of Auckland
Christoph C. Zielinski
Christoph C. Zielinski Medical University of Vienna
Stefan M. Pfister
Stefan M. Pfister German Cancer Research Center
Bettina Grasl-Kraupp
Bettina Grasl-Kraupp Medical University of Vienna
Marcel Kool
Marcel Kool German Cancer Research Center

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