Yves-Jean Bignon

Overview

Best Publications

• Genetic Heterogeneity and Penetrance Analysis of the BRCA1 and BRCA2 Genes in Breast Cancer Families

  D Ford;D F Easton;M Stratton;S Narod

  3894
  Citations

• Cancer risks associated with germline mutations in MLH1, MSH2, and MSH6 genes in Lynch syndrome.

  Valérie Bonadona;Bernard Bonaïti;Sylviane Olschwang;Sophie Grandjouan

  1212
  Citations

• Multifactorial Analysis of Differences Between Sporadic Breast Cancers and Cancers Involving BRCA1 and BRCA2 Mutations

  Sunil R. Lakhani;Jocelyne Jacquemier;John P Sloane;Barry A. Gusterson

  816
  Citations

• Prediction of BRCA1 Status in Patients with Breast Cancer Using Estrogen Receptor and Basal Phenotype

  Sunil R. Lakhani;Jorge S. Reis-Filho;Laura Fulford;Frederique Penault-Llorca

  810
  Citations

• The clinical value of somatic TP53 gene mutations in 1,794 patients with breast cancer.

  Magali Olivier;Anita Langerød;Patrizia Carrieri;Jonas Bergh

  669
  Citations

• A SUMOylation-defective MITF germline mutation predisposes to melanoma and renal carcinoma

  Corine Bertolotto;Fabienne Lesueur;Sandy Giuliano;Thomas Strub

  612
  Citations

• Identification of ten variants associated with risk of estrogen-receptor-negative breast cancer.

  Roger L Milne;Roger L Milne;Karoline B Kuchenbaecker;Karoline B Kuchenbaecker;Kyriaki Michailidou;Kyriaki Michailidou;Jonathan Beesley

  376
  Citations

• Genome-wide association study in BRCA1 mutation carriers identifies novel loci associated with breast and ovarian cancer risk

  Fergus J. Couch;Xianshu Wang;Lesley McGuffog;Andrew Lee

  372
  Citations

• MAX Mutations Cause Hereditary and Sporadic Pheochromocytoma and Paraganglioma

  Nelly Burnichon;Alberto Cascón;Francesca Schiavi;Nicole Paes Morales

  361
  Citations

• Pathology of ovarian cancers in BRCA1 and BRCA2 carriers.

  Sunil R. Lakhani;Sanjiv Manek;Frederique Penault-Llorca;Adrienne Flanagan

  348
  Citations

• RAD51 135G→C Modifies Breast Cancer Risk among BRCA2 Mutation Carriers: Results from a Combined Analysis of 19 Studies

  Antonis C. Antoniou;Olga M. Sinilnikova;Jacques Simard;Mélanie Léoné

  304
  Citations

• The pathology of familial breast cancer: histological features of cancers in families not attributable to mutations in BRCA1 or BRCA2.

  Sunil R. Lakhani;Barry A. Gusterson;Jocelyne Jacquemier;John P. Sloane

  296
  Citations

• Inhibition of BRCA1 leads to increased chemoresistance to microtubule-interfering agents, an effect that involves the JNK pathway.

  Stéphane Lafarge;Valérie Sylvain;Marc Ferrara;Yves-Jean Bignon

  262
  Citations

• Resveratrol and breast cancer chemoprevention: Molecular mechanisms

  Ludovic Le Corre;N. Chalabi;L. Delort;Yves-Jean Bignon

  222
  Citations

• Interplay between BRCA1 and RHAMM regulates epithelial apicobasal polarization and may influence risk of breast cancer.

  Christopher A. Maxwell;Javier Benitez;Laia Gomez-Baldo;Ana Osorio

  182
  Citations

• High allele loss rates at 17q12-q21 in breast and ovarian tumors from BRCAl-linked families. The Breast Cancer Linkage Consortium.

  R. S. Cornelis;S. L. Neuhausen;O. Johansson;A. Arason

  179
  Citations

• Significant contribution of large BRCA1 gene rearrangements in 120 French breast and ovarian cancer families.

  Sophie Gad;Virginie Caux-Moncoutier;Sabine Pagès-Berhouet;Marion Gauthier-Villars

  164
  Citations

• Evaluation of linkage of breast cancer to the putative BRCA3 locus on chromosome 13q21 in 128 multiple case families from the Breast Cancer Linkage Consortium

  Deborah Thompson;Csilla I. Szabo;Jon Mangion;Rogier A. Oldenburg

  147
  Citations

• The Exon 13 Duplication in the BRCA1 Gene Is a Founder Mutation Present in Geographically Diverse Populations

  S. Mazoyer;J. Leary;J. Kirk;E. Fleischmann

  143
  Citations

• Clinical practice guidelines for BRCA1 and BRCA2 genetic testing.

  Pascal Pujol;Massimo Barberis;Philp Beer;Eitan Friedman;Eitan Friedman

  143
  Citations