World's Best Scientists 2026 revealed!

D-Index & Metrics

Biology and Biochemistry

D-Index
74
Citations
25559
World Ranking
5491
National Ranking
354

Overview

Huiping Zhou is affiliated with the University of Tsukuba in Japan. Their research spans multiple areas predominantly within Medicine and Biochemistry, Genetics, and Molecular Biology, with a focus on epidemiology, molecular biology, surgery, hepatology, and oncology.

Their publication record includes significant contributions to the study of liver diseases, drug transport mechanisms, and metabolism, reflecting a strong emphasis on hepatic health and immunology. Zhou's work covers topics such as liver disease diagnosis and treatment, drug resistance, liver physiology and pathology, as well as pediatric hepatobiliary diseases.

  • Cholangiocyte-Derived Exosomal lncRNA H19 Promotes Macrophage Activation and Hepatic Inflammation under Cholestatic Conditions (2020, Cells)
  • Berberine inhibits free fatty acid and LPS-induced inflammation via modulating ER stress response in macrophages and hepatocytes (2020, PLoS ONE)
  • Protective and aggressive bacterial subsets and metabolites modify hepatobiliary inflammation and fibrosis in a murine model of PSC (2022, Gut)
  • Bile Acid Receptors and the Gut-Liver Axis in Nonalcoholic Fatty Liver Disease (2021, Cells)
  • Functional analysis of molecular and pharmacological modulators of mitochondrial fatty acid oxidation (2020, Scientific Reports)

Frequent collaborators contributing to Zhou's research include Phillip B. Hylemon, Derrick Zhao, Yunling Tai, Emily C. Gurley, and Lianyong Su. These coauthors appear across multiple studies in various capacities.

  • Phillip B. Hylemon
  • Derrick Zhao
  • Yunling Tai
  • Emily C. Gurley
  • Lianyong Su

Zhou's publications are found predominantly in journals and platforms such as Gastroenterology, SSRN Electronic Journal, bioRxiv (Cold Spring Harbor Laboratory), Cells, and Cell & Bioscience. These venues reflect a focused interest in clinical and molecular research in hepatic and gastrointestinal fields.

  • Gastroenterology
  • SSRN Electronic Journal
  • bioRxiv (Cold Spring Harbor Laboratory)
  • Cells
  • Cell & Bioscience

The subfields of Zhou's research demonstrate engagement with both clinical and molecular aspects, including epidemiology, molecular biology, surgery, hepatology, and oncology. This multidisciplinary approach underscores a comprehensive investigation into liver-related diseases and treatments.

  • Epidemiology
  • Molecular Biology
  • Surgery
  • Hepatology
  • Oncology

Main topics addressed in Zhou's body of work include:

  • Liver Disease Diagnosis and Treatment
  • Drug Transport and Resistance Mechanisms
  • Liver Diseases and Immunity
  • Diet, Metabolism, and Disease
  • Liver physiology and pathology
  • Pediatric Hepatobiliary Diseases and Treatments
  • Diet and metabolism studies

Best Publications

  • Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition)

    Daniel J. Klionsky;Kotb Abdelmohsen;Akihisa Abe;Joynal Abedin

  • Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition)

    Daniel J. Klionsky;Kotb Abdelmohsen;Akihisa Abe;Joynal Abedin

  • Bile acids as regulatory molecules.

    Phillip B. Hylemon;Huiping Zhou;William M. Pandak;Shunlin Ren

  • The plasma lipidomic signature of nonalcoholic steatohepatitis.

    Puneet Puri;Michelle M. Wiest;Onpan Cheung;Faridoddin Mirshahi

  • Increased Hepatic Synthesis and Dysregulation of Cholesterol Metabolism Is Associated with the Severity of Nonalcoholic Fatty Liver Disease

    Hae-Ki Min;Ashwani Kapoor;Michael Fuchs;Faridoddin Mirshahi

  • Prostaglandin catabolizing enzymes.

    Hsin-Hsiung Tai;Charles Mark Ensor;Min Tong;Huiping Zhou

  • The presence and severity of nonalcoholic steatohepatitis is associated with specific changes in circulating bile acids

    Puneet Puri;Kalyani Daita;Andrew Joyce;Faridoddin Mirshahi

  • Sphingosine-1-phosphate produced by sphingosine kinase 1 promotes breast cancer progression by stimulating angiogenesis and lymphangiogenesis.

    Masayuki Nagahashi;Subramaniam Ramachandran;Eugene Y. Kim;Jeremy C. Allegood

  • Conjugated bile acids activate the sphingosine-1-phosphate receptor 2 in primary rodent hepatocytes.

    Elaine Studer;Xiqiao Zhou;Renping Zhao;Yun Wang

  • Bile acids are nutrient signaling hormones.

    Huiping Zhou;Phillip B. Hylemon;Phillip B. Hylemon

  • Flavonoid apigenin inhibits lipopolysaccharide-induced inflammatory response through multiple mechanisms in macrophages.

    Xiaoxuan Zhang;Guangji Wang;Emily C. Gurley;Huiping Zhou

  • Lipotoxic Hepatocyte-Derived Exosomal MicroRNA 192-5p Activates Macrophages Through Rictor/Akt/Forkhead Box Transcription Factor O1 Signaling in Nonalcoholic Fatty Liver Disease

    Xiao-Lin Liu;Xiao-Lin Liu;Qin Pan;Hai-Xia Cao;Feng-Zhi Xin

  • Differential signalling by muscarinic receptors in smooth muscle: m2-mediated inactivation of myosin light chain kinase via Gi3, Cdc42/Rac1 and p21-activated kinase 1 pathway, and m3-mediated MLC20 (20 kDa regulatory light chain of myosin II) phosphorylation via Rho-associated kinase/myosin phosphatase targeting subunit 1 and protein kinase C/CPI-17 pathway.

    Karnam S Murthy;Huiping Zhou;John R Grider;David L Brautigan

  • Impaired Gut-Liver-Brain Axis in Patients with Cirrhosis

    Vishwadeep Ahluwalia;Naga S Betrapally;Phillip B Hylemon;Melanie B White

  • Crop diversity for yield increase.

    Chengyun Li;Xiahong He;Shusheng Zhu;Huiping Zhou

  • Prevention of free fatty acid–induced hepatic lipotoxicity by 18β-glycyrrhetinic acid through lysosomal and mitochondrial pathways

    Xudong Wu;Luyong Zhang;Emily Gurley;Elaine Studer

  • Cholangiocyte-Derived Exosomal Long Noncoding RNA H19 Promotes Hepatic Stellate Cell Activation and Cholestatic Liver Fibrosis.

    Runping Liu;Xiaojiaoyang Li;Weiwei Zhu;Weiwei Zhu;Yanyan Wang;Yanyan Wang

  • The role of sphingosine 1-phosphate receptor 2 in bile-acid-induced cholangiocyte proliferation and cholestasis-induced liver injury in mice.

    Yongqing Wang;Hiroaki Aoki;Jing Yang;Kesong Peng

  • Conjugated bile acid–activated S1P receptor 2 is a key regulator of sphingosine kinase 2 and hepatic gene expression

    Masayuki Nagahashi;Kazuaki Takabe;Runping Liu;Runping Liu;Kesong Peng

  • Colonic inflammation and secondary bile acids in alcoholic cirrhosis.

    Genta Kakiyama;Phillip B. Hylemon;Huiping Zhou;William Michael Pandak

Frequent Co-Authors

Phillip B. Hylemon
Phillip B. Hylemon Virginia Commonwealth University
William M. Pandak
William M. Pandak Virginia Commonwealth University
Karnam S. Murthy
Karnam S. Murthy Virginia Commonwealth University
Jasmohan S. Bajaj
Jasmohan S. Bajaj Virginia Commonwealth University
Arun J. Sanyal
Arun J. Sanyal Virginia Commonwealth University
Guangji Wang
Guangji Wang China Pharmaceutical University
Kazuaki Takabe
Kazuaki Takabe Roswell Park Cancer Institute
Patrick M. Gillevet
Patrick M. Gillevet George Mason University
Xiaokun Li
Xiaokun Li Wenzhou Medical University
Hsin-Hsiung Tai
Hsin-Hsiung Tai University of Kentucky

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