Karnam S. Murthy mainly investigates G protein, Cell biology, Biochemistry, Endocrinology and Internal medicine. Her G protein research is classified as research in Receptor. Her research integrates issues of Signal transduction and Acetylcholine in her study of Receptor.
Her Biochemistry study which covers Muscle relaxation that intersects with Biophysics and Ryanodine receptor. The study incorporates disciplines such as Vasoactive intestinal peptide and Calmodulin in addition to Endocrinology. Her work on G protein-coupled bile acid receptor, Glucagon and Glucose homeostasis as part of general Internal medicine study is frequently linked to Pancreatic islets, bridging the gap between disciplines.
Her primary areas of investigation include Endocrinology, Internal medicine, Cell biology, Receptor and Myocyte. Her Endocrinology research includes themes of Agonist, Vasoactive intestinal peptide and Protein kinase C. Her Cell biology study combines topics in areas such as Biochemistry and Smooth muscle.
Her Receptor study integrates concerns from other disciplines, such as Adenosine, Signal transduction and Acetylcholine. Her biological study spans a wide range of topics, including Biophysics and Inositol phosphate, Inositol. Her study explores the link between Phosphorylation and topics such as Molecular biology that cross with problems in Smooth muscle contraction.
Cell biology, Endocrinology, Internal medicine, Muscle contraction and Smooth muscle contraction are her primary areas of study. Karnam S. Murthy interconnects Receptor and Smooth muscle in the investigation of issues within Cell biology. Her Endocrinology research is multidisciplinary, incorporating perspectives in Erectile dysfunction, Peristalsis and Caveolin.
In general Internal medicine study, her work on Agonist often relates to the realm of Voltage clamp, thereby connecting several areas of interest. Her work deals with themes such as Muscle relaxation, Inflammation, Downregulation and upregulation and Rho-associated protein kinase, which intersect with Muscle contraction. Karnam S. Murthy combines subjects such as Molecular biology and Acetylcholine with her study of Muscle relaxation.
Karnam S. Murthy spends much of her time researching Internal medicine, Endocrinology, Cell biology, Muscle contraction and Rho-associated protein kinase. Her work blends Internal medicine and Bladder outlet obstruction studies together. She performs multidisciplinary study on Endocrinology and Cyclophosphamide in her works.
Her Cell biology research incorporates themes from Muscle relaxation, Biochemistry and Nicotine. Karnam S. Murthy has researched Muscle relaxation in several fields, including Myosin light-chain kinase, Myosin-light-chain phosphatase, Protein kinase C, Phosphorylation and Myosin. Her study in Rho-associated protein kinase is interdisciplinary in nature, drawing from both Interstitial cell of Cajal and RHOA.
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SIGNALING FOR CONTRACTION AND RELAXATION IN SMOOTH MUSCLE OF THE GUT
Karnam S. Murthy.
Annual Review of Physiology (2006)
Stimulation of nitric oxide from muscle cells by VIP: prejunctional enhancement of VIP release
J. R. Grider;K. S. Murthy;J. G. Jin;G. M. Makhlouf.
American Journal of Physiology-gastrointestinal and Liver Physiology (1992)
Differential signalling by muscarinic receptors in smooth muscle: m2-mediated inactivation of myosin light chain kinase via Gi3, Cdc42/Rac1 and p21-activated kinase 1 pathway, and m3-mediated MLC20 (20 kDa regulatory light chain of myosin II) phosphorylation via Rho-associated kinase/myosin phosphatase targeting subunit 1 and protein kinase C/CPI-17 pathway.
Karnam S Murthy;Huiping Zhou;John R Grider;David L Brautigan.
Biochemical Journal (2003)
Expression of endothelial nitric oxide synthase in human and rabbit gastrointestinal smooth muscle cells
B.-Q. Teng;K. S. Murthy;J. F. Kuemmerle;J. R. Grider.
American Journal of Physiology-gastrointestinal and Liver Physiology (1998)
Somatostatin Receptor-mediated Signaling in Smooth Muscle ACTIVATION OF PHOSPHOLIPASE C-β3 BY Gβγ AND INHIBITION OF ADENYLYL CYCLASE BY Gαi1 AND Gαo
Karnam S. Murthy;David H. Coy;Gabriel M. Makhlouf.
Journal of Biological Chemistry (1996)
Opioid mu, delta, and kappa receptor-induced activation of phospholipase C-beta 3 and inhibition of adenylyl cyclase is mediated by Gi2 and G(o) in smooth muscle.
K S Murthy;G M Makhlouf.
Molecular Pharmacology (1996)
Gi-1/Gi-2-dependent signaling by single-transmembrane natriuretic peptide clearance receptor
K. S. Murthy;B.-Q. Teng;H. Zhou;J.-G. Jin.
American Journal of Physiology-gastrointestinal and Liver Physiology (2000)
Activation of transmembrane bile acid receptor TGR5 stimulates insulin secretion in pancreatic β cells
Divya P. Kumar;Senthilkumar Rajagopal;Sunila Mahavadi;Faridoddin Mirshahi.
Biochemical and Biophysical Research Communications (2012)
G protein-dependent activation of smooth muscle eNOS via natriuretic peptide clearance receptor
K. S. Murthy;B.-Q. Teng;J.-G. Jin;G. M. Makhlouf.
American Journal of Physiology-cell Physiology (1998)
SIGNAL TRANSDUCTION IN GASTROINTESTINAL SMOOTH MUSCLE
Gabriel M Makhlouf;Karnam S Murthy.
Cellular Signalling (1997)
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