World's Best Scientists 2026 revealed!

D-Index & Metrics

Immunology

D-Index
95
Citations
35033
World Ranking
892
National Ranking
496

Medicine

D-Index
95
Citations
35033
World Ranking
10022
National Ranking
5160

Overview

Guido Silvestri is affiliated with Emory University in the United States. Their research primarily focuses on immunology and microbiology, with significant contributions in medicine. The main fields of study cover immunology and microbiology (144 publications) and medicine (111 publications). Within these, key subfields include immunology (73 publications), virology (70), infectious diseases (43), epidemiology (31), and molecular biology (21).

Silvestri's work addresses a range of topics, notably HIV research and treatment with 140 publications. Other important topics include immune cell function and interaction (54), T-cell and B-cell immunology (42), cytomegalovirus and herpesvirus research (36), HIV/AIDS research and interventions (28), immunotherapy and immune responses (24), and SARS-CoV-2 and COVID-19 research (22).

The scientist has published frequently in several venues, reflecting the diversity and scope of their research. These venues include bioRxiv (Cold Spring Harbor Laboratory) with 16 publications, UNC Libraries (12), Journal of Virology (9), Nature (5), and PLoS Pathogens (5).

Notable recent papers by Guido Silvestri include:

  • Systemic HIV and SIV latency reversal via non-canonical NF-κB signalling in vivo, 2020, Nature
  • Baricitinib treatment resolves lower-airway macrophage inflammation and neutrophil recruitment in SARS-CoV-2-infected rhesus macaques, 2020, Cell
  • Robust and persistent reactivation of SIV and HIV by N-803 and depletion of CD8+ cells, 2020, Nature
  • Long-primed germinal centres with enduring affinity maturation and clonal migration, 2022, Nature
  • A particulate saponin/TLR agonist vaccine adjuvant alters lymph flow and modulates adaptive immunity, 2021, Science Immunology

The researcher frequently collaborates with others in their field. Key co-authors include Diane G. Carnathan, Ann Chahroudi, Mirko Paiardini, Steven E. Bosinger, and Shane Crotty, with collaboration counts between 26 and 45 publications each.

Best Publications

  • Microbial translocation is a cause of systemic immune activation in chronic HIV infection

    Jason M. Brenchley;David A. Price;Timothy W. Schacker;Tedi E. Asher

  • Enhancing SIV-specific immunity in vivo by PD-1 blockade

    Vijayakumar Velu;Kehmia Titanji;Kehmia Titanji;Baogong Zhu;Sajid Husain;Sajid Husain

  • B cell–helper neutrophils stimulate the diversification and production of immunoglobulin in the marginal zone of the spleen

    Irene Puga;Montserrat Cols;Carolina M. Barra;Bing-Yang He

  • Nonpathogenic SIV infection of sooty mangabeys is characterized by limited bystander immunopathology despite chronic high-level viremia.

    Guido Silvestri;Donald L. Sodora;Richard A. Koup;Richard A. Koup;Mirko Paiardini

  • Differential Th17 CD4 T-cell depletion in pathogenic and nonpathogenic lentiviral infections

    Jason M. Brenchley;Mirko Paiardini;Kenneth S. Knox;Kenneth S. Knox;Ava I. Asher

  • Towards an HIV cure: a global scientific strategy

    Steven G Deeks;Brigitte Autran;Ben Berkhout;Monsef Benkirane

  • Microbial Translocation in the Pathogenesis of HIV Infection and AIDS

    Giulia Marchetti;Camilla Tincati;Guido Silvestri

  • Damaged intestinal epithelial integrity linked to microbial translocation in pathogenic simian immunodeficiency virus infections

    Jacob D. Estes;Levelle D. Harris;Nichole R. Klatt;Brian Tabb

  • Nonpathogenic SIV infection of African green monkeys induces a strong but rapidly controlled type I IFN response

    Béatrice Jacquelin;Véronique Mayau;Brice Targat;Anne Sophie Liovat

  • Nef-mediated suppression of T cell activation was lost in a lentiviral lineage that gave rise to HIV-1.

    Michael Schindler;Jan Münch;Olaf Kutsch;Hui Li

  • Type I interferon responses in rhesus macaques prevent SIV infection and slow disease progression

    Netanya G. Sandler;Netanya G. Sandler;Steven E. Bosinger;Jacob D. Estes;Richard T R Zhu

  • International AIDS Society global scientific strategy: towards an HIV cure 2016

    Steven G Deeks;Sharon R Lewin;Anna Laura Ross;Jintanat Ananworanich

  • Global genomic analysis reveals rapid control of a robust innate response in SIV-infected sooty mangabeys

    Steven E. Bosinger;Qingsheng Li;Shari N. Gordon;Nichole R. Klatt

  • A Blueprint for HIV Vaccine Discovery

    Dennis R. Burton;Rafi Ahmed;Rafi Ahmed;Dan H. Barouch;Dan H. Barouch;Dan H. Barouch;Salvatore T. Butera

  • Increased mortality and AIDS-like immunopathology in wild chimpanzees infected with SIVcpz

    Brandon F. Keele;Brandon F. Keele;James Holland Jones;Karen A. Terio;Jacob D. Estes

  • Slow Delivery Immunization Enhances HIV Neutralizing Antibody and Germinal Center Responses via Modulation of Immunodominance

    Kimberly M. Cirelli;Kimberly M. Cirelli;Diane G. Carnathan;Diane G. Carnathan;Diane G. Carnathan;Bartek Nogal;Jacob T. Martin;Jacob T. Martin

  • IL-7 administration drives T cell-cycle entry and expansion in HIV-1 infection.

    Irini Sereti;Richard M. Dunham;John Spritzler;Evgenia Aga

  • Cumulative mechanisms of lymphoid tissue fibrosis and T cell depletion in HIV-1 and SIV infections

    Ming Zeng;Anthony J. Smith;Stephen W. Wietgrefe;Peter J. Southern

  • TRIM Proteins Regulate Autophagy and Can Target Autophagic Substrates by Direct Recognition

    Michael A. Mandell;Ashish Jain;John Arko-Mensah;Santosh Chauhan

  • Natural SIV Hosts: Showing AIDS the Door

    Ann Chahroudi;Ann Chahroudi;Steven Bosinger;Thomas Howerton Vanderford;Mirko Paiardini;Mirko Paiardini

  • Immune activation and AIDS pathogenesis.

    Donald L Sodora;Guido Silvestri

Frequent Co-Authors

Mirko Paiardini
Mirko Paiardini Emory University
Ann Chahroudi
Ann Chahroudi Emory University
Steven E. Bosinger
Steven E. Bosinger Emory University
Donald L. Sodora
Donald L. Sodora Seattle Children's Hospital
Jacob D. Estes
Jacob D. Estes Oregon Health & Science University
Shane Crotty
Shane Crotty La Jolla Institute For Allergy & Immunology
Cristian Apetrei
Cristian Apetrei University of Pittsburgh
Ivona Pandrea
Ivona Pandrea University of Pittsburgh
Mark B. Feinberg
Mark B. Feinberg International AIDS Vaccine Initiative
Cynthia A. Derdeyn
Cynthia A. Derdeyn University of Washington

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