Michael M. Lederman

Research.com Recognitions

• 2011 - Fellow of the American Association for the Advancement of Science (AAAS)
• Member of the Association of American Physicians
• Member of the Association of American Physicians
• Member of the Association of American Physicians
• Member of the Association of American Physicians

Overview

Best Publications

• Circulating microRNAs in sera correlate with soluble biomarkers of immune activation but do not predict mortality in ART treated individuals with HIV-1 infection : a case control study

  Daniel D. Murray;Kazuo Suzuki;Matthew Law;Jonel Trebicka

  4700
  Citations

• Microbial translocation is a cause of systemic immune activation in chronic HIV infection

  Jason M. Brenchley;David A. Price;Timothy W. Schacker;Tedi E. Asher

  4316
  Citations

• HIV nonprogressors preferentially maintain highly functional HIV-specific CD8+ T-cells

  Michael R. Betts;Martha C. Nason;Sadie M. West;Stephen C. De Rosa

  2278
  Citations

• The major genetic determinants of HIV-1 control affect HLA class I peptide presentation

  Pereyra F;Jia X;McLaren Pj

  1679
  Citations

• A Trial Comparing Nucleoside Monotherapy with Combination Therapy in HIV-Infected Adults with CD4 Cell Counts from 200 to 500 per Cubic Millimeter

  Scott M. Hammer;David A. Katzenstein;Michael D. Hughes;Holly Gundacker

  1397
  Citations

• Dysbiosis of the Gut Microbiota Is Associated with HIV Disease Progression and Tryptophan Catabolism

  Ivan Vujkovic-Cvijin;Richard M. Dunham;Shoko Iwai;Michael C. Maher

  833
  Citations

• Plasma Levels of Bacterial DNA Correlate with Immune Activation and the Magnitude of Immune Restoration in Persons with Antiretroviral-Treated HIV Infection

  Wei Jiang;Michael M. Lederman;Peter Hunt;Scott F. Sieg

  738
  Citations

• HIV-infected individuals with low CD4/CD8 ratio despite effective antiretroviral therapy exhibit altered T cell subsets, heightened CD8+ T cell activation, and increased risk of non-AIDS morbidity and mortality.

  Sergio Serrano-Villar;Talia Sainz;Sulggi A. Lee;Peter W. Hunt

  736
  Citations

• A Prospective Study of Human Immunodeficiency Virus Type 1 Infection and the Development of AIDS in Subjects with Hemophilia

  James J. Goedert;Craig M. Kessler;Louis M. Aledort;Robert J. Biggar

  708
  Citations

• Immunologic Responses Associated with 12 Weeks of Combination Antiretroviral Therapy Consisting of Zidovudine, Lamivudine, and Ritonavir: Results of AIDS Clinical Trials Group Protocol 315

  Michael Marcel Lederman;Elizabeth Connick;Alan Landay;Daniel R. Kuritzkes

  627
  Citations

• Soluble Markers of Inflammation and Coagulation but Not T-Cell Activation Predict Non–AIDS-Defining Morbid Events During Suppressive Antiretroviral Treatment

  Allan R. Tenorio;Yu Zheng;Ronald J. Bosch;Supriya Krishnan

  605
  Citations

• Human epithelial β-defensins 2 and 3 inhibit HIV-1 replication

  Miguel E Quiñones-Mateu;Michael M Lederman;Zhimin Feng;Bikram Chakraborty

  594
  Citations

• Towards an HIV cure: a global scientific strategy

  Steven G Deeks;Brigitte Autran;Ben Berkhout;Monsef Benkirane

  592
  Citations

• Gut Epithelial Barrier Dysfunction and Innate Immune Activation Predict Mortality in Treated HIV Infection

  Peter W. Hunt;Elizabeth Sinclair;Benigno Rodriguez;Carey Shive

  574
  Citations

• A potential role for interleukin-7 in T-cell homeostasis

  Terry J. Fry;Elizabeth Connick;Judith Falloon;Michael Marcel Lederman

  523
  Citations

• Prevention of Vaginal SHIV Transmission in Rhesus Macaques Through Inhibition of CCR5

  Michael M Lederman;Ronald S Veazey;Robin Ewart Offord;Donald E Mosier

  484
  Citations

• Safety, pharmacokinetics, and antiviral activity of AMD3100, a selective CXCR4 receptor inhibitor, in HIV-1 infection

  Craig W. Hendrix;Ann C. Collier;Michael Marcel Lederman;Dominique Schols

  465
  Citations

• Human β-defensin-3 activates professional antigen-presenting cells via Toll-like receptors 1 and 2

  Nicholas Funderburg;Michael M. Lederman;Zhimin Feng;Michael G. Drage

  451
  Citations

• Impaired Cell-Mediated Immunity in Patients with Classic Hemophilia

  Michael M. Lederman;Oscar D. Ratnoff;James J. Scillian;Paul K. Jones

  448
  Citations

• Inadequate T follicular cell help impairs B cell immunity during HIV infection

  Rafael A. Cubas;Joseph C. Mudd;Anne Laure Savoye;Matthieu Perreau

  441
  Citations

• Perforin Expression Directly Ex Vivo by HIV-Specific CD8 + T-Cells Is a Correlate of HIV Elite Control

  Adam R. Hersperger;Florencia Pereyra;Martha Nason;Korey R. Demers

  431
  Citations

• Predictive value of plasma HIV RNA level on rate of CD4 T-cell decline in untreated HIV infection.

  Benigno Rodríguez;Ajay K. Sethi;Vinay K. Cheruvu;Wilma Mackay

  419
  Citations

• IL-7 administration drives T cell-cycle entry and expansion in HIV-1 infection.

  Irini Sereti;Richard M. Dunham;John Spritzler;Evgenia Aga

  408
  Citations

• Diagnosis of nosocomial pneumonia in intubated, intensive care unit patients.

  R. A. Salata;M. M. Lederman;D. M. Shlaes;M. R. Jacobs

  383
  Citations