D-Index & Metrics Best Publications

D-Index & Metrics D-index (Discipline H-index) only includes papers and citation values for an examined discipline in contrast to General H-index which accounts for publications across all disciplines.

Discipline name D-index D-index (Discipline H-index) only includes papers and citation values for an examined discipline in contrast to General H-index which accounts for publications across all disciplines. Citations Publications World Ranking National Ranking
Immunology D-index 101 Citations 46,291 424 World Ranking 396 National Ranking 242
Medicine D-index 101 Citations 46,756 450 World Ranking 4653 National Ranking 2603

Research.com Recognitions

Awards & Achievements

2011 - Fellow of the American Association for the Advancement of Science (AAAS)

Member of the Association of American Physicians

Overview

What is he best known for?

The fields of study he is best known for:

  • Internal medicine
  • Immune system
  • Gene

Michael M. Lederman spends much of his time researching Immunology, Acquired immunodeficiency syndrome, Internal medicine, Immune system and Immunopathology. Immunology connects with themes related to Virology in his study. His biological study spans a wide range of topics, including Clinical trial and Cohort study.

Chemotherapy, Thrombocytopenic purpura and Chronic idiopathic thrombocytopenic purpura is closely connected to Gastroenterology in his research, which is encompassed under the umbrella topic of Internal medicine. The Immune system study combines topics in areas such as HEK 293 cells, Lipopolysaccharide and Disease. His Immunopathology research includes themes of Lymphocyte proliferation, Antibody, Immunization, Antigen and Virus.

His most cited work include:

  • Microbial translocation is a cause of systemic immune activation in chronic HIV infection (2742 citations)
  • Circulating microRNAs in sera correlate with soluble biomarkers of immune activation but do not predict mortality in ART treated individuals with HIV-1 infection : a case control study (2421 citations)
  • HIV nonprogressors preferentially maintain highly functional HIV-specific CD8+ T-cells (1572 citations)

What are the main themes of his work throughout his whole career to date?

The scientist’s investigation covers issues in Immunology, Virology, Internal medicine, Acquired immunodeficiency syndrome and Immune system. His work in Immunology addresses subjects such as Cytotoxic T cell, which are connected to disciplines such as Molecular biology. His Internal medicine study incorporates themes from Gastroenterology, Endocrinology, Surgery and Oncology.

His study in Acquired immunodeficiency syndrome is interdisciplinary in nature, drawing from both Viral disease, Clinical trial and Disease. He has researched Immune system in several fields, including Interleukin, Cytokine, Lymphocyte and Antigen. His studies deal with areas such as Inflammation and CD38 as well as CD8.

He most often published in these fields:

  • Immunology (64.13%)
  • Virology (23.54%)
  • Internal medicine (18.16%)

What were the highlights of his more recent work (between 2014-2021)?

  • Immunology (64.13%)
  • Inflammation (10.31%)
  • Internal medicine (18.16%)

In recent papers he was focusing on the following fields of study:

His primary areas of study are Immunology, Inflammation, Internal medicine, T cell and Immune system. His research integrates issues of Cytotoxic T cell and Virology in his study of Immunology. The various areas that Michael M. Lederman examines in his Inflammation study include Fibrosis, Pathogenesis and Lymph.

His study on Internal medicine also encompasses disciplines like

  • Oncology, which have a strong connection to Acquired immunodeficiency syndrome,
  • Endocrinology, which have a strong connection to Raltegravir and Emtricitabine. As part of the same scientific family, he usually focuses on T cell, concentrating on Antiretroviral therapy and intersecting with Immune activation. In his work, IRF3 is strongly intertwined with Senescence, which is a subfield of Immune system.

Between 2014 and 2021, his most popular works were:

  • Circulating microRNAs in sera correlate with soluble biomarkers of immune activation but do not predict mortality in ART treated individuals with HIV-1 infection : a case control study (2421 citations)
  • The size of the expressed HIV reservoir predicts timing of viral rebound after treatment interruption (157 citations)
  • Rosuvastatin reduces vascular inflammation and T-cell and monocyte activation in HIV-infected subjects on antiretroviral therapy (107 citations)

In his most recent research, the most cited papers focused on:

  • Internal medicine
  • Immune system
  • Gene

His main research concerns Immunology, Inflammation, Internal medicine, CD8 and Immune system. His studies in Immunology integrate themes in fields like Cytotoxic T cell and Antiretroviral therapy. His Internal medicine research integrates issues from Gastroenterology, Acquired immunodeficiency syndrome and Oncology.

The concepts of his Acquired immunodeficiency syndrome study are interwoven with issues in Malignancy, Logistic regression, Viremia, Circulating MicroRNA and Peripheral blood mononuclear cell. His work in CD8 addresses issues such as T cell, which are connected to fields such as microRNA, Case-control study, TFAM and Cell cycle. His Immune system research includes themes of Virology, Interleukin, Flow cytometry and Mitochondrion, Mitochondrial biogenesis.

This overview was generated by a machine learning system which analysed the scientist’s body of work. If you have any feedback, you can contact us here.

Best Publications

Circulating microRNAs in sera correlate with soluble biomarkers of immune activation but do not predict mortality in ART treated individuals with HIV-1 infection : a case control study

Daniel D. Murray;Kazuo Suzuki;Matthew Law;Jonel Trebicka.
PLOS ONE (2015)

4699 Citations

Microbial translocation is a cause of systemic immune activation in chronic HIV infection

Jason M. Brenchley;David A. Price;Timothy W. Schacker;Tedi E. Asher.
Nature Medicine (2006)

3869 Citations

HIV nonprogressors preferentially maintain highly functional HIV-specific CD8+ T-cells

Michael R. Betts;Martha C. Nason;Sadie M. West;Stephen C. De Rosa.
Blood (2006)

2163 Citations

The major genetic determinants of HIV-1 control affect HLA class I peptide presentation

Pereyra F;Jia X;McLaren Pj.
Science (2010)

1535 Citations

A Trial Comparing Nucleoside Monotherapy with Combination Therapy in HIV-Infected Adults with CD4 Cell Counts from 200 to 500 per Cubic Millimeter

Scott M. Hammer;David A. Katzenstein;Michael D. Hughes;Holly Gundacker.
The New England Journal of Medicine (1996)

1269 Citations

A Prospective Study of Human Immunodeficiency Virus Type 1 Infection and the Development of AIDS in Subjects with Hemophilia

James J. Goedert;Craig M. Kessler;Louis M. Aledort;Robert J. Biggar.
The New England Journal of Medicine (1989)

706 Citations

Plasma Levels of Bacterial DNA Correlate with Immune Activation and the Magnitude of Immune Restoration in Persons with Antiretroviral-Treated HIV Infection

Wei Jiang;Michael M. Lederman;Peter Hunt;Scott F. Sieg.
The Journal of Infectious Diseases (2009)

693 Citations

Immunologic Responses Associated with 12 Weeks of Combination Antiretroviral Therapy Consisting of Zidovudine, Lamivudine, and Ritonavir: Results of AIDS Clinical Trials Group Protocol 315

Michael Marcel Lederman;Elizabeth Connick;Alan Landay;Daniel R. Kuritzkes.
The Journal of Infectious Diseases (1998)

618 Citations

Dysbiosis of the Gut Microbiota Is Associated with HIV Disease Progression and Tryptophan Catabolism

Ivan Vujkovic-Cvijin;Richard M. Dunham;Shoko Iwai;Michael C. Maher.
Science Translational Medicine (2013)

614 Citations

HIV-infected individuals with low CD4/CD8 ratio despite effective antiretroviral therapy exhibit altered T cell subsets, heightened CD8+ T cell activation, and increased risk of non-AIDS morbidity and mortality.

Sergio Serrano-Villar;Talia Sainz;Sulggi A. Lee;Peter W. Hunt.
PLOS Pathogens (2014)

583 Citations

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