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Immunology

D-Index
90
Citations
31875
World Ranking
1070
National Ranking
577

Medicine

D-Index
90
Citations
31685
World Ranking
12159
National Ranking
6236

Research.com Recognitions

  • 2012 - Fellow of the American Association for the Advancement of Science (AAAS)

Overview

Clifford V. Harding is affiliated with Case Western Reserve University in the United States. Their scholarly work primarily spans medicine, with a significant focus on immunology and microbiology.

Their research interests encompass several specialized subfields including infectious diseases, immunology, neurology, cardiology and cardiovascular medicine, and hematology. The main themes explored in their work include COVID-19 clinical research studies, SARS-CoV-2 and COVID-19 research, immune response and inflammation, cardiovascular effects of exercise, long-term effects of COVID-19, SARS-CoV-2 detection and testing, and iron metabolism and disorders.

Frequent coauthors involved in collaborations with Clifford V. Harding include Mina K. Chung, Nancy Nagy, W. Henry Boom, Dhanunjaya Lakkireddy, and Thomas F. Deering.

Publication venues where their research has appeared more than once include The Journal of Immunology and also single publications in EBioMedicine, American Journal of Clinical Pathology, Journal of Alzheimer s Disease, and JACC. Clinical electrophysiology.

Recent selected papers authored or coauthored by Clifford V. Harding include:

  • SARS-CoV-2 and ACE2: The biology and clinical data settling the ARB and ACEI controversy (2020, EBioMedicine)
  • Molecular Detection of SARS-CoV-2 Infection in FFPE Samples and Histopathologic Findings in Fatal SARS-CoV-2 Cases (2020, American Journal of Clinical Pathology)
  • Upregulation of Local Hepcidin Contributes to Iron Accumulation in Alzheimer's Disease Brains (2021, Journal of Alzheimer s Disease)
  • Guidance for Rebooting Electrophysiology Through the COVID-19 Pandemic From the Heart Rhythm Society and the American Heart Association Electrocardiography and Arrhythmias Committee of the Council on Clinical Cardiology (2020, JACC. Clinical electrophysiology)
  • Guidance for rebooting electrophysiology through the COVID-19 pandemic from the Heart Rhythm Society and the American Heart Association Electrocardiography and Arrhythmias Committee of the Council on Clinical Cardiology (2020, Heart Rhythm)

Clifford V. Harding was recognized as a Fellow of the American Association for the Advancement of Science (AAAS) in 2012.

Best Publications

  • B lymphocytes secrete antigen-presenting vesicles.

    G Raposo;H W Nijman;W Stoorvogel;R Liejendekker

  • Receptor-mediated endocytosis of transferrin and recycling of the transferrin receptor in rat reticulocytes

    C Harding;J Heuser;P Stahl

  • CpG oligodeoxynucleotides act as adjuvants that switch on T helper 1 (Th1) immunity.

    Rose S. Chu;Oleg S. Targoni;Arthur M. Krieg;Paul V. Lehmann

  • Phagocytic processing of bacterial antigens for class I MHC presentation to T cells

    John D. Pfeifer;Mary Jo Wick;Richard L. Roberts;Kirk Findlay

  • Quantitation of antigen-presenting cell MHC class II/peptide complexes necessary for T-cell stimulation

    Clifford V. Harding;Emil R. Unanue

  • Toll-Like Receptor 2-Dependent Inhibition of Macrophage Class II MHC Expression and Antigen Processing by 19-kDa Lipoprotein of Mycobacterium tuberculosis

    Erika H. Noss;Rish K. Pai;Timothy J. Sellati;Justin D. Radolf

  • Regulation of antigen presentation by Mycobacterium tuberculosis: a role for Toll-like receptors

    Clifford V. Harding;W. Henry Boom

  • Receptor-mediated endocytosis.

    T. Wileman;Clifford V Harding;P. Stahl

  • Exosomes: Looking back three decades and into the future

    Clifford V. Harding;John E. Heuser;Philip D. Stahl

  • Phagocytic processing of exogenous particulate antigens by macrophages for presentation by class I MHC molecules.

    Clifford V Harding;Rui Song

  • Endocytosis and intracellular processing of transferrin and colloidal gold-transferrin in rat reticulocytes: demonstration of a pathway for receptor shedding.

    Clifford V Harding;J. Heuser;P. Stahl

  • Human β-defensin-3 activates professional antigen-presenting cells via Toll-like receptors 1 and 2

    Nicholas Funderburg;Michael M. Lederman;Zhimin Feng;Michael G. Drage

  • COVID-19 and Cardiovascular Disease: From Bench to Bedside.

    Mina K. Chung;David A. Zidar;Michael R. Bristow;Scott J. Cameron

  • Mycobacterium tuberculosis LprG (Rv1411c): a novel TLR-2 ligand that inhibits human macrophage class II MHC antigen processing.

    Adam J. Gehring;Karen M. Dobos;John T. Belisle;Clifford V. Harding

  • Intracellular signalling cascades regulating innate immune responses to Mycobacteria: branching out from Toll-like receptors

    Eun Kyeong Jo;Chul Su Yang;Chul Hee Choi;Clifford V. Harding

  • Inhibition of IFN-γ-Induced Class II Transactivator Expression by a 19-kDa Lipoprotein from Mycobacterium tuberculosis: A Potential Mechanism for Immune Evasion

    Rish K. Pai;Marilyn Convery;Thomas A. Hamilton;W. Henry Boom

  • Liposome-encapsulated antigens are processed in lysosomes, recycled, and presented to T cells.

    Clifford V Harding;David S Collins;Jan W Slot;Hans J Geuze

  • Reduction of disulfide bonds within lysosomes is a key step in antigen processing

    David S. Collins;Emil R. Unanue;Clifford V. Harding

  • Mycobacterial lipoprotein activates autophagy via TLR2/1/CD14 and a functional vitamin D receptor signalling

    Dong Min Shin;Jae Min Yuk;Hye Mi Lee;Sang Hee Lee

  • Extracellular vesicles and infectious diseases: new complexity to an old story

    Jeffrey S. Schorey;Clifford V. Harding

  • Pathways of antigen processing

    Clifford V. Harding

Frequent Co-Authors

W. Henry Boom
W. Henry Boom Case Western Reserve University
Michael M. Lederman
Michael M. Lederman Case Western Reserve University
Emil R. Unanue
Emil R. Unanue Washington University in St. Louis
Benigno Rodriguez
Benigno Rodriguez Case Western Reserve University
Wei Jiang
Wei Jiang Wuhan University
Aaron A.R. Tobian
Aaron A.R. Tobian Johns Hopkins University School of Medicine
Arthur M. Krieg
Arthur M. Krieg University of Massachusetts Chan Medical School
Philip D. Stahl
Philip D. Stahl Washington University in St. Louis
Staffan Normark
Staffan Normark Karolinska Institute
Xiaoxia Li
Xiaoxia Li Cleveland Clinic Lerner College of Medicine

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