D-Index & Metrics Best Publications

D-Index & Metrics

Discipline name D-index D-index (Discipline H-index) only includes papers and citation values for an examined discipline in contrast to General H-index which accounts for publications across all disciplines. Citations Publications World Ranking National Ranking
Immunology D-index 95 Citations 31,772 234 World Ranking 338 National Ranking 212
Medicine D-index 98 Citations 33,325 245 World Ranking 4048 National Ranking 2297

Research.com Recognitions

Awards & Achievements

2019 - Distinguished Fellows of the American Association of Immunologists (AAI)

2014 - AAI Lifetime Achievement Award, American Association of Immunologists

2005 - Robert Koch Gold Medal

1989 - Fellow of the American Academy of Arts and Sciences

1987 - Member of the National Academy of Sciences

1980 - Fellow of John Simon Guggenheim Memorial Foundation

Overview

What is he best known for?

The fields of study he is best known for:

  • Gene
  • Immune system
  • Enzyme

Emil R. Unanue mainly focuses on Immunology, Antigen, Macrophage, Microbiology and Molecular biology. His Immunology research is multidisciplinary, relying on both Natural killer cell and Cell biology. His Antigen study incorporates themes from Antigen presentation, B cell and Antigen-presenting cell.

Myocyte, Efferocytosis and CCR2 is closely connected to Monocyte in his research, which is encompassed under the umbrella topic of Macrophage. Emil R. Unanue has researched Microbiology in several fields, including Listeria monocytogenes and Antibody. His Molecular biology research includes themes of Cell culture, Transfection, T cell, Lymphocyte and Peptide.

His most cited work include:

  • Batf3 Deficiency Reveals a Critical Role for CD8α+ Dendritic Cells in Cytotoxic T Cell Immunity (1245 citations)
  • Antigen-Presenting Function of the Macrophage (957 citations)
  • The basis for the immunoregulatory role of macrophages and other accessory cells. (908 citations)

What are the main themes of his work throughout his whole career to date?

His scientific interests lie mostly in Immunology, Antigen, Molecular biology, Major histocompatibility complex and Antigen presentation. His Immunology research incorporates themes from Listeria monocytogenes, Macrophage and Microbiology. His study of T lymphocyte is a part of Antigen.

Emil R. Unanue focuses mostly in the field of Molecular biology, narrowing it down to matters related to T cell and, in some cases, B cell. His work carried out in the field of Major histocompatibility complex brings together such families of science as Epitope, Peptide and Cell biology. His research in Antigen presentation intersects with topics in Autoimmunity and Antigen-presenting cell.

He most often published in these fields:

  • Immunology (39.19%)
  • Antigen (30.27%)
  • Molecular biology (25.95%)

What were the highlights of his more recent work (between 2010-2021)?

  • Immunology (39.19%)
  • Antigen (30.27%)
  • Antigen presentation (21.89%)

In recent papers he was focusing on the following fields of study:

Emil R. Unanue focuses on Immunology, Antigen, Antigen presentation, Major histocompatibility complex and Immune system. Emil R. Unanue works mostly in the field of Immunology, limiting it down to topics relating to Islet and, in certain cases, Cell biology, Homeostasis and Pancreas. His Antigen research focuses on subjects like Molecular biology, which are linked to Interferon gamma.

His research investigates the link between Antigen presentation and topics such as Inflammation that cross with problems in Beta cell. Emil R. Unanue does research in Immune system, focusing on MHC class I specifically. In his research on the topic of T cell, Insulin, Epitope and Germinal center is strongly related with Type 1 diabetes.

Between 2010 and 2021, his most popular works were:

  • Embryonic and Adult-Derived Resident Cardiac Macrophages Are Maintained through Distinct Mechanisms at Steady State and during Inflammation (723 citations)
  • TREM2 Maintains Microglial Metabolic Fitness in Alzheimer's Disease. (333 citations)
  • Early, transient depletion of plasmacytoid dendritic cells ameliorates autoimmunity in a lupus model (175 citations)

In his most recent research, the most cited papers focused on:

  • Gene
  • Immune system
  • Enzyme

The scientist’s investigation covers issues in Immunology, Immune system, Antigen, Antigen presentation and Autoimmunity. His work in Immunology addresses subjects such as Diabetes mellitus, which are connected to disciplines such as Blocking antibody. His Immune system study combines topics from a wide range of disciplines, such as Precursor cell and Granulocyte macrophage colony-stimulating factor.

His Antigen study incorporates themes from Adoptive cell transfer and B cell. Emil R. Unanue interconnects CCR2, MHC class II, Molecular biology, Monocyte and Myocyte in the investigation of issues within Antigen presentation. His Cell biology study combines topics in areas such as Cytotoxic T cell and Interleukin 12.

This overview was generated by a machine learning system which analysed the scientist’s body of work. If you have any feedback, you can contact us here.

Best Publications

Antigen-Presenting Function of the Macrophage

Emil R. Unanue.
Annual Review of Immunology (1984)

1516 Citations

The basis for the immunoregulatory role of macrophages and other accessory cells.

Emil R. Unanue;Paul M. Allen.
Science (1987)

1426 Citations

Batf3 Deficiency Reveals a Critical Role for CD8α+ Dendritic Cells in Cytotoxic T Cell Immunity

Kai Hildner;Brian T. Edelson;Whitney E. Purtha;Mark Diamond.
Science (2008)

1370 Citations

Interleukin 12 and tumor necrosis factor alpha are costimulators of interferon gamma production by natural killer cells in severe combined immunodeficiency mice with listeriosis, and interleukin 10 is a physiologic antagonist.

Catherine S. Tripp;Stanley F. Wolf;Emil R. Unanue.
Proceedings of the National Academy of Sciences of the United States of America (1993)

1123 Citations

Embryonic and Adult-Derived Resident Cardiac Macrophages Are Maintained through Distinct Mechanisms at Steady State and during Inflammation

Slava Epelman;Kory J. Lavine;Anna E. Beaudin;Dorothy K. Sojka.
Immunity (2014)

770 Citations

CD2-associated protein haploinsufficiency is linked to glomerular disease susceptibility.

Jeong M. Kim;Hui Wu;Gopa Green;Cheryl A. Winkler.
Science (2003)

611 Citations

Identification of a membrane-associated interleukin 1 in macrophages.

Evelyn A. Kurt-Jones;David I. Beller;Steven B. Mizel;Emil R. Unanue.
Proceedings of the National Academy of Sciences of the United States of America (1985)

585 Citations

Interleukin 1 is processed and released during apoptosis.

Kristin A. Hogquist;Michelle A. Nett;Emil R. Unanue;David D. Chaplin.
Proceedings of the National Academy of Sciences of the United States of America (1991)

570 Citations

Quantitation of antigen-presenting cell MHC class II/peptide complexes necessary for T-cell stimulation

Clifford V. Harding;Emil R. Unanue.
Nature (1990)

563 Citations

Identification of a macrophage antigen-processing event required for I-region-restricted antigen presentation to T lymphocytes.

Kirk Ziegler;Emil R. Unanue.
Journal of Immunology (1981)

503 Citations

Best Scientists Citing Emil R. Unanue

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Michael L. Dustin

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Kenneth M. Murphy

Kenneth M. Murphy

Washington University in St. Louis

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Stefan H. E. Kaufmann

Max Planck Institute for Infection Biology

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John W. Kappler

John W. Kappler

University of Colorado Anschutz Medical Campus

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Florent Ginhoux

Florent Ginhoux

Agency for Science, Technology and Research

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Paul M. Allen

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Washington University in St. Louis

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Pascale Cossart

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Charles A. Dinarello

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University of Colorado Denver

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Bernard Malissen

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Aix-Marseille University

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Philippa Marrack

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John A. Corbett

John A. Corbett

Medical College of Wisconsin

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Alessandro Sette

Alessandro Sette

La Jolla Institute For Allergy & Immunology

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Ronald N. Germain

Ronald N. Germain

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Marco Colonna

Marco Colonna

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Mark M. Davis

Mark M. Davis

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Profile was last updated on December 6th, 2021.
Research.com Ranking is based on data retrieved from the Microsoft Academic Graph (MAG).
The ranking d-index is inferred from publications deemed to belong to the considered discipline.

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