2026 Emil R. Unanue: Immunology Researcher – H-Index, Publications & Awards

Discipline name	D-Index	World Ranking	National Ranking	Publications	Citations
Immunology	113	435	267	368	44226
Medicine	113	4983	2705	367	44226

Research.com Recognitions

2019 - Distinguished Fellows of the American Association of Immunologists (AAI)
2014 - AAI Lifetime Achievement Award, American Association of Immunologists
2005 - Robert Koch Gold Medal
1989 - Fellow of the American Academy of Arts and Sciences
1987 - Member of the National Academy of Sciences
1980 - Fellow of John Simon Guggenheim Memorial Foundation

Overview

Emil R. Unanue was affiliated with Washington University in St. Louis in the United States. Their research centered primarily on biochemistry, genetics, molecular biology, medicine, immunology, and microbiology.

The scientist's work frequently appeared in publication venues such as:

The Journal of Immunology
The Journal of Experimental Medicine
Nature Immunology
Nature
Cell

Key topics covered in their research included:

Diabetes and associated disorders
Pancreatic function and diabetes
Immune cell function and interaction
Diabetes management and research
Immune cells in cancer
Neuroinflammation and neurodegeneration mechanisms
Immunotherapy and immune responses

Among their frequent collaborators were:

Xiaoxiao Wan
Orion J. Peterson
Anthony N. Vomund
Cheryl F. Lichti
Hao Hu

Notable recent papers included:

"Endogenous self-peptides guard immune privilege of the central nervous system," 2024, Nature
"TREM2 Modulation Remodels the Tumor Myeloid Landscape Enhancing Anti-PD-1 Immunotherapy," 2020, Cell
"Single-cell RNA sequencing of murine islets shows high cellular complexity at all stages of autoimmune diabetes," 2020, The Journal of Experimental Medicine
"The MHC-II peptidome of pancreatic islets identifies key features of autoimmune peptides," 2020, Nature Immunology
"Cytocidal macrophages in symbiosis with CD4 and CD8 T cells cause acute diabetes following checkpoint blockade of PD-1 in NOD mice," 2020, Proceedings of the National Academy of Sciences

Emil R. Unanue contributed substantially to understanding autoimmune diabetes and immune regulation related to pancreatic function, as reflected in their publication record. Their work involved detailed molecular and cellular analyses within immunology, genetics, and biochemistry fields.

Throughout their career, Unanue received several prestigious recognitions including:

Member of the National Academy of Sciences, 1987
Fellow of the American Academy of Arts and Sciences, 1989
Fellow of John Simon Guggenheim Memorial Foundation, 1980
Robert Koch Gold Medal, 2005
AAI Lifetime Achievement Award, American Association of Immunologists, 2014
Distinguished Fellows of the American Association of Immunologists (AAI), 2019

Best Publications

Batf3 Deficiency Reveals a Critical Role for CD8α+ Dendritic Cells in Cytotoxic T Cell Immunity

Kai Hildner;Brian T. Edelson;Whitney E. Purtha;Mark Diamond

2290
Citations
Antigen-Presenting Function of the Macrophage

Emil R. Unanue

1643
Citations
Embryonic and adult-derived resident cardiac macrophages are maintained through distinct mechanisms at steady state and during inflammation.

Slava Epelman;Kory J. Lavine;Anna E. Beaudin;Dorothy K. Sojka

1566
Citations
The basis for the immunoregulatory role of macrophages and other accessory cells.

Emil R. Unanue;Paul M. Allen

1497
Citations
TREM2 Maintains Microglial Metabolic Fitness in Alzheimer's Disease.

Tyler K. Ulland;Wilbur M. Song;Stanley Ching Cheng Huang;Jason D. Ulrich

1204
Citations
Interleukin 12 and tumor necrosis factor alpha are costimulators of interferon gamma production by natural killer cells in severe combined immunodeficiency mice with listeriosis, and interleukin 10 is a physiologic antagonist.

Catherine S. Tripp;Stanley F. Wolf;Emil R. Unanue

1160
Citations
CD2-associated protein haploinsufficiency is linked to glomerular disease susceptibility.

Jeong M. Kim;Hui Wu;Gopa Green;Cheryl A. Winkler

653
Citations
Identification of a membrane-associated interleukin 1 in macrophages.

Evelyn A. Kurt-Jones;David I. Beller;Steven B. Mizel;Emil R. Unanue

649
Citations
Quantitation of antigen-presenting cell MHC class II/peptide complexes necessary for T-cell stimulation

Clifford V. Harding;Emil R. Unanue

633
Citations
Interleukin 1 is processed and released during apoptosis.

Kristin A. Hogquist;Michelle A. Nett;Emil R. Unanue;David D. Chaplin

594
Citations
Identification of a macrophage antigen-processing event required for I-region-restricted antigen presentation to T lymphocytes.

Kirk Ziegler;Emil R. Unanue

518
Citations
Antigen Receptor Engagement Delivers a Stop Signal to Migrating T Lymphocytes

Michael L. Dustin;Shannon K. Bromley;Zhengyan Kan;Daniel A. Peterson

486
Citations
Type I Interferon Sensitizes Lymphocytes to Apoptosis and Reduces Resistance to Listeria Infection

Javier A. Carrero;Boris Calderon;Emil R. Unanue

478
Citations
REQUIREMENT OF THYMUS (T) LYMPHOCYTES FOR RESISTANCE TO LISTERIOSIS

F. C. Lane;Emil Unanue

472
Citations
Natural immunity: a T-cell-independent pathway of macrophage activation, defined in the scid mouse.

Gregory J. Bancroft;Robert D. Schreiber;Emil R. Unanue

442
Citations
The costimulatory function of antigen-presenting cells

Casey T Weaver;Emil R Unanue

437
Citations
A mAb recognizing a surface antigen of Mycobacterium tuberculosis enhances host survival.

Rachel Teitelbaum;Aharona Glatman-Freedman;Bing Chen;John B. Robbins

402
Citations
Identification of the T-cell and Ia contact residues of a T-cell antigenic epitope

Paul M. Allen;Gary R. Matsueda;Robert J. Evans;James B. Dunbar

396
Citations
Neutrophils are involved in acute, nonspecific resistance to Listeria monocytogenes in mice.

H W Rogers;E R Unanue

390
Citations
Studies in listeriosis show the strong symbiosis between the innate cellular system and the T‐cell response

Emil R. Unanue

379
Citations

Frequent Co-Authors

Osami Kanagawa École Normale Supérieure de Lyon

Paul M. Allen Washington University in St. Louis

Michael L. Gross Washington University in St. Louis

Clifford V. Harding Case Western Reserve University

Kenneth M. Murphy Washington University in St. Louis

Jonathan Braun Cedars-Sinai Medical Center

David D. Chaplin University of Alabama at Birmingham

Mark J. Miller Washington University in St. Louis

Robert D. Schreiber Washington University in St. Louis

Robert C. Fuhlbrigge University of Colorado Anschutz Medical Campus

External Links

Wikipedia of Emil R. Unanue Personal website of Emil R. Unanue

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