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Biology and Biochemistry

D-Index
77
Citations
18773
World Ranking
4842
National Ranking
2332

Overview

John A. Corbett is affiliated with the Medical College of Wisconsin in the United States. Their research primarily spans the fields of Biochemistry, Genetics and Molecular Biology, with significant contributions to Medicine. The scientist's work includes focused studies in several subfields such as Molecular Biology, Surgery, Physiology, Genetics, and Cell Biology.

The main topics addressed in their research include pancreatic function and diabetes, diabetes and associated disorders, calcium signaling and nucleotide metabolism, adenosine and purinergic signaling, immune cell function and interaction, protein degradation and inhibitors, and redox biology and oxidative stress.

John A. Corbett has a record of published research in various scientific journals. Frequent publication venues for their work include the Journal of Biological Chemistry, Diabetes, American Journal of Physiology-Regulatory, Integrative and Comparative Physiology, Frontiers in Endocrinology, and Function.

Their recent publications include:

  • Mitophagy protects β cells from inflammatory damage in diabetes, 2020, JCI Insight
  • SurfaceGenie: a web-based application for prioritizing cell-type-specific marker candidates, 2020, Bioinformatics
  • Peroxiredoxin 1 plays a primary role in protecting pancreatic β-cells from hydrogen peroxide and peroxynitrite, 2020, American Journal of Physiology-Regulatory, Integrative and Comparative Physiology
  • The Role of Thioredoxin/Peroxiredoxin in the β-Cell Defense Against Oxidative Damage, 2021, Frontiers in Endocrinology
  • Single-cell RNA sequencing of mouse islets exposed to proinflammatory cytokines, 2021, Life Science Alliance

Frequent collaborators in John A. Corbett's research include Jennifer S. Stancill, Polly A. Hansen, Chay Teng Yeo, Aaron Naatz, and Bryndon J. Oleson. They have co-authored multiple papers together, underscoring recurring partnerships in their scientific investigations.

Best Publications

  • Selective inhibition of the inducible nitric oxide synthase by aminoguanidine.

    Thomas P. Misko;William M. Moore;Thomas P. Kasten;G.Allen Nickols

  • Aminoguanidine, a Novel Inhibitor of Nitric Oxide Formation, Prevents Diabetic Vascular Dysfunction

    John A. Corbett;Ronald G. Tilton;Kathy Chang;Khalid S. Hasan

  • Nitric oxide mediates cytokine-induced inhibition of insulin secretion by human islets of Langerhans.

    John A. Corbett;Michael A. Sweetland;Jin Lin Wang;Jack R. Lancaster

  • Does nitric oxide mediate autoimmune destruction of beta-cells? Possible therapeutic interventions in IDDM.

    John A Corbett;Michael L McDaniel

  • Interleukin 1 beta induces the formation of nitric oxide by beta-cells purified from rodent islets of Langerhans. Evidence for the beta-cell as a source and site of action of nitric oxide.

    J. A. Corbett;Jin Lin Wang;M. A. Sweetland;J. R. Lancaster

  • Prevention of diabetic vascular dysfunction by guanidines. Inhibition of nitric oxide synthase versus advanced glycation end-product formation.

    Ronald G Tilton;Katherine Chang;Khalid S Hasan;Samuel R Smith

  • Expression of Neuregulins and their Putative Receptors, ErbB2 and ErbB3, Is Induced during Wallerian Degeneration

    Steven L. Carroll;Michele L. Miller;Paul W. Frohnert;Susanne S. Kim

  • Interleukin-1 beta-induced formation of EPR-detectable iron-nitrosyl complexes in islets of Langerhans. Role of nitric oxide in interleukin-1 beta-induced inhibition of insulin secretion.

    J A Corbett;J R Lancaster;M A Sweetland;M L McDaniel

  • Cytokines and nitric oxide in islet inflammation and diabetes.

    Michael L. McDaniel;Guim Kwon;Jeanette R. Hill;Connie A. Marshall

  • IL-1 produced and released endogenously within human islets inhibits beta cell function.

    M Arnush;M R Heitmeier;A L Scarim;M H Marino

  • Release of nitric oxide during the T cell-independent pathway of macrophage activation. Its role in resistance to Listeria monocytogenes.

    K P Beckerman;H W Rogers;J A Corbett;R D Schreiber

  • The role of reactive oxygen species and proinflammatory cytokines in type 1 diabetes pathogenesis

    Lindsey E. Padgett;Katarzyna A. Broniowska;Polly A. Hansen;John A. Corbett

  • Targeted Overactivity of β Cell KATP Channels Induces Profound Neonatal Diabetes

    J.C Koster;B.A Marshall;N Ensor;J.A Corbett

  • Intraislet release of interleukin 1 inhibits beta cell function by inducing beta cell expression of inducible nitric oxide synthase.

    John A. Corbett;Michael L. McDaniel

  • IL-1 beta induces the coexpression of both nitric oxide synthase and cyclooxygenase by islets of Langerhans: activation of cyclooxygenase by nitric oxide.

    John A. Corbett;Guim Kwon;John Turk;Michael L. McDaniel

  • Luminol-Based Chemiluminescent Signals: Clinical and Non-clinical Application and Future Uses

    Parvez Khan;Danish Idrees;Michael A. Moxley;John A. Corbett

  • Biochemical Evidence for Nitric Oxide Formation from Streptozotocin in Isolated Pancreatic Islets

    John Turk;John A. Corbett;Sasanka Ramanadham;Alan Bohrer

  • Interleukin-1 beta-induced nitric oxide synthase expression by rat pancreatic beta-cells: evidence for the involvement of nuclear factor kappa B in the signaling mechanism.

    Guim Kwon;John A. Corbett;Charles P. Rodi;Patrick Sullivan

  • Interleukin-1 Plus γ-Interferon-Induced Pancreatic β-Cell Dysfunction Is Mediated by β-Cell Nitric Oxide Production

    Helen E. Thomas;Rima Darwiche;John A. Corbett;Thomas W.H. Kay

  • Selective inhibition of inducible nitric oxide synthase by aminoguanidine.

    John A. Corbett;Michael L. McDaniel

Frequent Co-Authors

Michael L. McDaniel
Michael L. McDaniel Washington University in St. Louis
Neil Hogg
Neil Hogg Medical College of Wisconsin
John Turk
John Turk Washington University in St. Louis
Jack R. Lancaster
Jack R. Lancaster University of Pittsburgh
Willis K. Samson
Willis K. Samson Saint Louis University
Abdul Waheed
Abdul Waheed Saint Louis University
Richard W. Gross
Richard W. Gross Washington University in St. Louis
Mark G. Currie
Mark G. Currie Ironwood Pharmaceuticals (United States)
Harris Perlman
Harris Perlman Northwestern University
Susan Bonner-Weir
Susan Bonner-Weir Harvard University

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