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Chemistry

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1728
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653

Biology and Biochemistry

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99
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Overview

Richard W. Gross is affiliated with Washington University in St. Louis in the United States and focuses primarily on research within the fields of Biochemistry, Genetics and Molecular Biology, and Medicine. Their work encompasses multiple subfields, including Molecular Biology, Physiology, Biochemistry, Spectroscopy, and Cardiology and Cardiovascular Medicine.

The major topics of Richard W. Gross's research include:

  • Mitochondrial Function and Pathology
  • Adipose Tissue and Metabolism
  • Peroxisome Proliferator-Activated Receptors
  • Cardiovascular Function and Risk Factors
  • Sphingolipid Metabolism and Signaling
  • Eicosanoids and Hypertension Pharmacology
  • Metabolomics and Mass Spectrometry Studies

Notable recent papers authored or co-authored by Richard W. Gross include:

  • The foundations and development of lipidomics, 2021, Journal of Lipid Research
  • Nutritional modulation of heart failure in mitochondrial pyruvate carrier-deficient mice, 2020, Nature Metabolism
  • 12-LOX catalyzes the oxidation of 2-arachidonoyl-lysolipids in platelets generating eicosanoid-lysolipids that are attenuated by iPLA2γ knockout, 2020, Journal of Biological Chemistry
  • A functional role for eicosanoid-lysophospholipids in activating monocyte signaling, 2020, Journal of Biological Chemistry
  • High-fat diet activates liver iPLA2γ generating eicosanoids that mediate metabolic stress, 2021, Journal of Lipid Research

The primary venues where Richard W. Gross frequently publishes include:

  • Journal of Lipid Research (3 publications)
  • Journal of Biological Chemistry (2 publications)
  • Nature Metabolism (1 publication)
  • Frontiers in Cardiovascular Medicine (1 publication)
  • iScience (1 publication)

Richard W. Gross often collaborates with several co-authors, including:

  • Christopher M. Jenkins (4 joint publications)
  • Harold F. Sims (4 joint publications)
  • Shaoping Guan (4 joint publications)
  • Beverly Gibson Dilthey (4 joint publications)
  • Xinping Liu (3 joint publications)

Best Publications

  • Shotgun lipidomics: Electrospray ionization mass spectrometric analysis and quantitation of cellular lipidomes directly from crude extracts of biological samples

    Xianlin Han;Richard W. Gross

  • Identification, cloning, expression, and purification of three novel human calcium-independent phospholipase A2 family members possessing triacylglycerol lipase and acylglycerol transacylase activities

    Richard W. Gross;Christopher Jenkins

  • The cardiac phenotype induced by PPARα overexpression mimics that caused by diabetes mellitus

    Brian N. Finck;John J. Lehman;Teresa C. Leone;Michael J. Welch

  • Global analyses of cellular lipidomes directly from crude extracts of biological samples by ESI mass spectrometry: A bridge to lipidomics

    Xianlin Han;Richard W. Gross

  • Lipid rafts are enriched in arachidonic acid and plasmenylethanolamine and their composition is independent of caveolin-1 expression: a quantitative electrospray ionization/mass spectrometric analysis.

    Linda J. Pike;Xianlin Han;Koong Nah Chung;Richard W. Gross

  • A critical role for PPARα-mediated lipotoxicity in the pathogenesis of diabetic cardiomyopathy: Modulation by dietary fat content

    Brian N. Finck;Xianlin Han;Michael Courtois;Franck Aimond

  • Amphipathic metabolites and membrane dysfunction in ischemic myocardium.

    P B Corr;R W Gross;B E Sobel

  • Multi-dimensional mass spectrometry-based shotgun lipidomics and novel strategies for lipidomic analyses.

    Xianlin Han;Kui Yang;Richard W. Gross

  • Electrospray ionization mass spectroscopic analysis of human erythrocyte plasma membrane phospholipids

    Xianlin Han;Richard W. Gross

  • Quantitative analysis and molecular species fingerprinting of triacylglyceride molecular species directly from lipid extracts of biological samples by electrospray ionization tandem mass spectrometry.

    Xianlin Han;Richard W. Gross

  • Ferroptotic cell death and TLR4/Trif signaling initiate neutrophil recruitment after heart transplantation

    Wenjun Li;Guoshuai Feng;Jason M. Gauthier;Inessa Lokshina

  • Adipocyte Lipases and Defect of Lipolysis in Human Obesity

    Dominique Langin;Andrea Dicker;Geneviève Tavernier;Johan Hoffstedt

  • Suicide inhibition of canine myocardial cytosolic calcium-independent phospholipase A2. Mechanism-based discrimination between calcium-dependent and -independent phospholipases A2.

    Stanley L. Hazen;Lori A. Zupan;Randy H. Weiss;Daniel P. Getman

  • Automated lipid identification and quantification by multidimensional mass spectrometry-based shotgun lipidomics.

    Kui Yang;Hua Cheng;Richard W. Gross;Xianlin Han

  • High plasmalogen and arachidonic acid content of canine myocardial sarcolemma: a fast atom bombardment mass spectroscopic and gas chromatography-mass spectroscopic characterization.

    Richard W. Gross

  • DGAT enzymes are required for triacylglycerol synthesis and lipid droplets in adipocytes

    Charles A. Harris;Joel T. Haas;Ryan S. Streeper;Scot J. Stone

  • Decreased hepatic triglyceride accumulation and altered fatty acid uptake in mice with deletion of the liver fatty acid-binding protein gene.

    Elizabeth P. Newberry;Yan Xie;Susan Kennedy;Xianlin Han

  • Nuclear receptors PPARβ/δ and PPARα direct distinct metabolic regulatory programs in the mouse heart

    Eileen M. Burkart;Nandakumar Sambandam;Xianlin Han;Richard W. Gross

  • CD36 Is Important for Fatty Acid and Cholesterol Uptake by the Proximal but Not Distal Intestine

    Fatiha Nassir;Brody Wilson;Xianlin Han;Richard W. Gross

  • Purification and characterization of canine myocardial cytosolic phospholipase A2. A calcium-independent phospholipase with absolute f1-2 regiospecificity for diradyl glycerophospholipids.

    Stanley L. Hazen;Robert J. Stuppy;Richard W. Gross

Frequent Co-Authors

Xianlin Han
Xianlin Han The University of Texas Health Science Center at San Antonio
John Turk
John Turk Washington University in St. Louis
Sasanka Ramanadham
Sasanka Ramanadham University of Alabama at Birmingham
Stanley L. Hazen
Stanley L. Hazen Cleveland Clinic Lerner College of Medicine
Burton E. Sobel
Burton E. Sobel Washington University in St. Louis
Jeffrey E. Saffitz
Jeffrey E. Saffitz Beth Israel Deaconess Medical Center
Nada A. Abumrad
Nada A. Abumrad Washington University in St. Louis
Brian N. Finck
Brian N. Finck Washington University in St. Louis
Daniel P. Kelly
Daniel P. Kelly University of Pennsylvania
John A. Corbett
John A. Corbett Medical College of Wisconsin

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