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Kristopher T. Kahle

Kristopher T. Kahle

Yale University
United States

D-Index & Metrics

Biology and Biochemistry

D-Index
71
Citations
16315
World Ranking
6724
National Ranking
3121

Kristopher T. Kahle publication distribution in Biology and Biochemistry in 2026

The chart shows the distribution of publications by all Research.com ranked scientists in the field of Biology and Biochemistry in 2026. The highlighted bar marks where Kristopher T. Kahle sits on this spectrum.

47–56 publications: 8 scientists 57–66 publications: 35 scientists 67–76 publications: 106 scientists 77–86 publications: 231 scientists 87–96 publications: 414 scientists 97–106 publications: 546 scientists 107–116 publications: 704 scientists 117–126 publications: 849 scientists 127–136 publications: 980 scientists 137–146 publications: 942 scientists 147–156 publications: 969 scientists 157–166 publications: 950 scientists 167–176 publications: 951 scientists 177–186 publications: 915 scientists 187–196 publications: 787 scientists 197–206 publications: 841 scientists 207–216 publications: 735 scientists 217–226 publications: 709 scientists 227–236 publications: 651 scientists 237–246 publications: 605 scientists 247–256 publications: 510 scientists 257–266 publications: 524 scientists 267–276 publications: 434 scientists 277–286 publications: 418 scientists 287–296 publications: 350 scientists 297–306 publications: 363 scientists 307–316 publications: 315 scientists 317–326 publications: 296 scientists 327–336 publications: 261 scientists 337–346 publications: 240 scientists 347–356 publications: 219 scientists 357–366 publications: 197 scientists 367–376 publications: 154 scientists 377–386 publications: 161 scientists 387–396 publications: 155 scientists 397–406 publications: 145 scientists 407–416 publications: 124 scientists 417–426 publications: 112 scientists 427–436 publications: 132 scientists 437–446 publications: 116 scientists 447–456 publications: 99 scientists 457–466 publications: 81 scientists 467–476 publications: 91 scientists 477–486 publications: 80 scientists 487–496 publications: 80 scientists 497–506 publications: 60 scientists 507–516 publications: 36 scientists 517–526 publications: 46 scientists 527–536 publications: 54 scientists 537–546 publications: 44 scientists 547–556 publications: 43 scientists 557–566 publications: 43 scientists 567–576 publications: 42 scientists 577–586 publications: 25 scientists 587–596 publications: 34 scientists 597–606 publications: 23 scientists 607–616 publications: 33 scientists 617–626 publications: 31 scientists 627–636 publications: 27 scientists 637–646 publications: 25 scientists 647–656 publications: 28 scientists 657–666 publications: 34 scientists 667–676 publications: 18 scientists 677–686 publications: 16 scientists 687–696 publications: 10 scientists 697–706 publications: 12 scientists 707–716 publications: 21 scientists 717–726 publications: 12 scientists 727–736 publications: 12 scientists 737–746 publications: 10 scientists 747–756 publications: 7 scientists 757–766 publications: 13 scientists 767–776 publications: 15 scientists 777–786 publications: 13 scientists 787–796 publications: 9 scientists 797–806 publications: 9 scientists 807–816 publications: 7 scientists 817–826 publications: 4 scientists 827–836 publications: 9 scientists 837–846 publications: 7 scientists 847–856 publications: 3 scientists 857–866 publications: 5 scientists 867–876 publications: 5 scientists 877–886 publications: 11 scientists 887–896 publications: 3 scientists 897–906 publications: 4 scientists 907–916 publications: 7 scientists 917–926 publications: 5 scientists 927–936 publications: 6 scientists 937–946 publications: 6 scientists 947–956 publications: 3 scientists 957–966 publications: 7 scientists 967–976 publications: 2 scientists 977–986 publications: 2 scientists 987–996 publications: 1 scientists 997–1,006 publications: 5 scientists 1,007–1,016 publications: 2 scientists 1,017–1,026 publications: 2 scientists 1,027 publications: 1 scientists 1,028+ publications: 100 scientists
47 publications 1,028+

This scientist: 223 publications — 58th percentile

58% of scientists in this discipline score the same or lower.

The last bar groups every scientist with 1,028 publications or more.

Kristopher T. Kahle D-index placement in Biology and Biochemistry in 2026

The chart shows the D-index (discipline H-index) distribution of Biology and Biochemistry scientists ranked by Research.com in 2026. The highlighted bar marks where Kristopher T. Kahle sits on this spectrum.

40–41 D-Index: 80 scientists 42–43 D-Index: 183 scientists 44–45 D-Index: 317 scientists 46–47 D-Index: 504 scientists 48–49 D-Index: 718 scientists 50–51 D-Index: 900 scientists 52–53 D-Index: 1,026 scientists 54–55 D-Index: 1,150 scientists 56–57 D-Index: 1,236 scientists 58–59 D-Index: 1,253 scientists 60–61 D-Index: 1,163 scientists 62–63 D-Index: 1,131 scientists 64–65 D-Index: 1,032 scientists 66–67 D-Index: 897 scientists 68–69 D-Index: 814 scientists 70–71 D-Index: 715 scientists 72–73 D-Index: 709 scientists 74–75 D-Index: 596 scientists 76–77 D-Index: 512 scientists 78–79 D-Index: 473 scientists 80–81 D-Index: 412 scientists 82–83 D-Index: 373 scientists 84–85 D-Index: 358 scientists 86–87 D-Index: 285 scientists 88–89 D-Index: 273 scientists 90–91 D-Index: 227 scientists 92–93 D-Index: 208 scientists 94–95 D-Index: 193 scientists 96–97 D-Index: 153 scientists 98–99 D-Index: 157 scientists 100–101 D-Index: 148 scientists 102–103 D-Index: 120 scientists 104–105 D-Index: 113 scientists 106–107 D-Index: 100 scientists 108–109 D-Index: 86 scientists 110–111 D-Index: 67 scientists 112–113 D-Index: 72 scientists 114–115 D-Index: 73 scientists 116–117 D-Index: 64 scientists 118–119 D-Index: 53 scientists 120–121 D-Index: 60 scientists 122–123 D-Index: 54 scientists 124–125 D-Index: 43 scientists 126–127 D-Index: 38 scientists 128–129 D-Index: 49 scientists 130–131 D-Index: 26 scientists 132–133 D-Index: 18 scientists 134–135 D-Index: 23 scientists 136–137 D-Index: 32 scientists 138–139 D-Index: 32 scientists 140–141 D-Index: 27 scientists 142–143 D-Index: 19 scientists 144–145 D-Index: 22 scientists 146–147 D-Index: 12 scientists 148–149 D-Index: 16 scientists 150–151 D-Index: 14 scientists 152–153 D-Index: 10 scientists 154–155 D-Index: 13 scientists 156–157 D-Index: 10 scientists 158–159 D-Index: 7 scientists 160–161 D-Index: 9 scientists 162–163 D-Index: 13 scientists 164–165 D-Index: 4 scientists 166 D-Index: 4 scientists 167+ D-Index: 98 scientists
40 D-Index 167+

This scientist: 71 D-Index — 67th percentile

67% of scientists in this discipline score the same or lower.

The last bar groups every scientist with 167 D-Index or more.

Overview

Kristopher T. Kahle is affiliated with Yale University in the United States and has made significant contributions across several areas of medicine and neuroscience. Their research has primarily focused on neurological disorders, with a particular emphasis on cerebrospinal fluid dynamics and hydrocephalus.

Their recent publications include the following papers:

  • Glymphatic System Impairment in Alzheimer's Disease and Idiopathic Normal Pressure Hydrocephalus, 2020, Trends in Molecular Medicine
  • Inflammation in acquired hydrocephalus: pathogenic mechanisms and therapeutic targets, 2020, Nature Reviews Neurology
  • Exome sequencing implicates genetic disruption of prenatal neuro-gliogenesis in sporadic congenital hydrocephalus, 2020, Nature Medicine
  • The choroid plexus links innate immunity to CSF dysregulation in hydrocephalus, 2023, Cell
  • Modulation of brain cation-Cl− cotransport via the SPAK kinase inhibitor ZT-1a, 2020, Nature Communications

Frequently collaborating with other researchers, Kahle's prominent co-authors include:

  • Phan Q. Duy
  • Adam J. Kundishora
  • Sheng Chih Jin
  • Seth L. Alper
  • Benjamin C. Reeves

The scientist often publishes in journals and venues such as:

  • Neurosurgery
  • bioRxiv (Cold Spring Harbor Laboratory)
  • Cerebral Cortex
  • Journal of Neurosurgery Pediatrics
  • World Neurosurgery

Kahle's work spans multiple fields of study with a total of nearly 200 publications in medicine, alongside extensive work in biochemistry, genetics, and molecular biology. Neuroscience is another major area of focus, which includes investigations into cellular and molecular neuroscience and neurology subfields.

Specific subfields of their research include:

  • Neurology
  • Genetics
  • Cellular and Molecular Neuroscience
  • Pediatrics, Perinatology and Child Health
  • Molecular Biology

Their main research topics cover a spectrum of neurological and developmental disorders:

  • Cerebrospinal fluid and hydrocephalus
  • Fetal and Pediatric Neurological Disorders
  • Traumatic Brain Injury and Neurovascular Disturbances
  • Genetic and Kidney Cyst Diseases
  • Craniofacial Disorders and Treatments
  • Spinal Dysraphism and Malformations
  • Neuroscience and Neuropharmacology Research

Best Publications

  • The GABA Excitatory/Inhibitory Shift in Brain Maturation and Neurological Disorders:

    Yehezkel Ben-Ari;Ilgam Khalilov;Kristopher T Kahle;Enrico Cherubini

  • A SUMOylation-dependent transcriptional subprogram is required for Myc-driven tumorigenesis.

    Jessica D. Kessler;Kristopher T. Kahle;Kristopher T. Kahle;Tingting Sun;Kristen L. Meerbrey

  • Roles of the cation–chloride cotransporters in neurological disease

    Kristopher T Kahle;Kevin J Staley;Brian V Nahed;Gerardo Gamba

  • Molecular pathogenesis of inherited hypertension with hyperkalemia: the Na-Cl cotransporter is inhibited by wild-type but not mutant WNK4.

    Frederick H. Wilson;Kristopher T. Kahle;Ernesto Sabath;Maria D. Lalioti

  • WNK4 regulates the balance between renal NaCl reabsorption and K + secretion

    Kahle Kt;Wilson Fh;Wilson Fh;Leng Q;Lalioti;Lalioti

  • Wnk4 controls blood pressure and potassium homeostasis via regulation of mass and activity of the distal convoluted tubule.

    Maria D Lalioti;Junhui Zhang;Heather M Volkman;Kristopher T Kahle

  • EGFR mutation status and survival after diagnosis of brain metastasis in nonsmall cell lung cancer

    April F. Eichler;Kristopher T. Kahle;Daphne L. Wang;Victoria A. Joshi

  • Inflammation-dependent cerebrospinal fluid hypersecretion by the choroid plexus epithelium in posthemorrhagic hydrocephalus

    Jason K Karimy;Jinwei Zhang;Jinwei Zhang;David B Kurland;Brianna Carusillo Theriault

  • Molecular mechanisms of ischemic cerebral edema: role of electroneutral ion transport.

    Kristopher T. Kahle;J. Marc Simard;Kevin J. Staley;Brian V. Nahed

  • Glymphatic System Impairment in Alzheimer's Disease and Idiopathic Normal Pressure Hydrocephalus.

    Benjamin C. Reeves;Jason K. Karimy;Adam J. Kundishora;Humberto Mestre

  • The WNK-SPAK/OSR1 pathway: Master regulator of cation-chloride cotransporters

    Dario R. Alessi;Jinwei Zhang;Arjun Khanna;Thomas Hochdörfer

  • WNK3 modulates transport of Cl- in and out of cells: Implications for control of cell volume and neuronal excitability

    Kristopher T. Kahle;Jesse Rinehart;Paola de los Heros;Angeliki Louvi

  • Angiotensin II signaling increases activity of the renal Na-Cl cotransporter through a WNK4-SPAK-dependent pathway

    Pedro San-Cristobal;Diana Pacheco-Alvarez;Diana Pacheco-Alvarez;Ciaran Richardson;Aaron M. Ring

  • Phosphoregulation of the Na-K-2Cl and K-Cl cotransporters by the WNK kinases

    Kristopher T. Kahle;Jesse Rinehart;Richard P. Lifton

  • Molecular physiology of the WNK kinases.

    Kristopher T. Kahle;Aaron M. Ring;Richard P. Lifton

  • Regulation of NKCC2 by a chloride-sensing mechanism involving the WNK3 and SPAK kinases.

    José Ponce-Coria;Pedro San-Cristobal;Kristopher T. Kahle;Norma Vazquez

  • Local Impermeant Anions Establish the Neuronal Chloride Concentration

    J. Glykys;V. Dzhala;K. Egawa;T Balena

  • Progressive NKCC1-Dependent Neuronal Chloride Accumulation during Neonatal Seizures

    Volodymyr I. Dzhala;Kishore V. Kuchibhotla;Joseph C. Glykys;Kristopher T. Kahle

  • Modulation of neuronal activity by phosphorylation of the K–Cl cotransporter KCC2

    Kristopher T. Kahle;Kristopher T. Kahle;Tarek Z. Deeb;Martin Puskarjov;Liliya Silayeva

  • The WNK-regulated SPAK/OSR1 kinases directly phosphorylate and inhibit the K+–Cl− co-transporters

    Paola De Los Heros;Dario R. Alessi;Robert Gourlay;David G. Campbell

Frequent Co-Authors

Richard P. Lifton
Richard P. Lifton Rockefeller University
Seth L. Alper
Seth L. Alper Beth Israel Deaconess Medical Center
Dandan Sun
Dandan Sun University of Pittsburgh
Kevin J. Staley
Kevin J. Staley Harvard University
Gerardo Gamba
Gerardo Gamba National Autonomous University of Mexico
Murat Gunel
Murat Gunel Yale University
Steven C. Hebert
Steven C. Hebert Yale University
Eric Delpire
Eric Delpire Vanderbilt University
Aaron M. Ring
Aaron M. Ring Yale University
Guy A. Rouleau
Guy A. Rouleau Montreal Neurological Institute and Hospital

External Links

Personal website of Kristopher T. Kahle

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Best Scientists Citing Kristopher T. Kahle

Gerardo Gamba

Gerardo Gamba

National Autonomous University of Mexico

Publications: 84

Eric Delpire

Eric Delpire

Vanderbilt University

Publications: 60

David H. Ellison

David H. Ellison

Oregon Health & Science University

Publications: 59

Shinichi Uchida

Shinichi Uchida

Tokyo Medical and Dental University

Publications: 46

Wen-Hui Wang

Wen-Hui Wang

New York Medical College

Publications: 46

Stephen J. Moss

Stephen J. Moss

Tufts University

Publications: 36

Claudio Rivera

Claudio Rivera

University of Helsinki

Publications: 34

Chou Long Huang

Chou Long Huang

University of Iowa Hospitals and Clinics

Publications: 33

Dandan Sun

Dandan Sun

University of Pittsburgh

Publications: 29

Richard P. Lifton

Richard P. Lifton

Rockefeller University

Publications: 28

Melanie H. Cobb

Melanie H. Cobb

The University of Texas Southwestern Medical Center

Publications: 28

Kai Kaila

Kai Kaila

University of Helsinki

Publications: 28

Chad J. Creighton

Chad J. Creighton

Baylor College of Medicine

Publications: 26

Sei Sasaki

Sei Sasaki

Tokyo Medical and Dental University

Publications: 25

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Yehezkel Ben-Ari

Neurochlore (France)

Publications: 25

Florian Lang

Florian Lang

University of Tübingen

Publications: 24

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