World's Best Scientists 2026 revealed!

D-Index & Metrics

Biology and Biochemistry

D-Index
92
Citations
31832
World Ranking
2208
National Ranking
1193

Research.com Recognitions

  • 1997 - Fellow of the American Association for the Advancement of Science (AAAS)

Overview

Seth L. Alper is affiliated with the Beth Israel Deaconess Medical Center in the United States. Their research primarily spans the fields of Medicine, with significant contributions to Biochemistry, Genetics, and Molecular Biology. Within these broad areas, their subfields of study include Molecular Biology, Genetics, Physiology, Nephrology, and Pediatrics, Perinatology, and Child Health.

The main research topics covered by their work involve Fetal and Pediatric Neurological Disorders, Erythrocyte Function and Pathophysiology, Cerebrospinal Fluid and Hydrocephalus, Genetic and Kidney Cyst Diseases, Renal Diseases and Glomerulopathies, Renal and Related Cancers, and Ion Channel Regulation and Function.

Some of the notable recent papers authored include:

  • Glymphatic System Impairment in Alzheimer's Disease and Idiopathic Normal Pressure Hydrocephalus, 2020, Trends in Molecular Medicine
  • Inflammation in acquired hydrocephalus: pathogenic mechanisms and therapeutic targets, 2020, Nature Reviews Neurology
  • Exome sequencing implicates genetic disruption of prenatal neuro-gliogenesis in sporadic congenital hydrocephalus, 2020, Nature Medicine
  • The choroid plexus links innate immunity to CSF dysregulation in hydrocephalus, 2023, Cell
  • Modulation of brain cation-Cl− cotransport via the SPAK kinase inhibitor ZT-1a, 2020, Nature Communications

Seth L. Alper has frequently collaborated with several coauthors, including Kristopher T. Kahle, Phan Q. Duy, Sheng Chih Jin, Benjamin C. Reeves, and Carol Nelson-Williams.

Their work has been published in various venues, with multiple publications appearing in bioRxiv (Cold Spring Harbor Laboratory), Journal of the American Society of Nephrology, Proceedings of the National Academy of Sciences, The FASEB Journal, and Neurosurgery.

In recognition of their contributions to science, Seth L. Alper was awarded the title of Fellow of the American Association for the Advancement of Science (AAAS) in 1997.

Best Publications

  • Hemodynamic shear stress and its role in atherosclerosis.

    Adel M. Malek;Seth L. Alper;Seigo Izumo

  • Drought- and salt-tolerant plants result from overexpression of the AVP1 H+-pump

    Roberto A. Gaxiola;Jisheng Li;Soledad Undurraga;Lien M. Dang

  • The Arabidopsis thaliana proton transporters, AtNhx1 and Avp1, can function in cation detoxification in yeast.

    Roberto A. Gaxiola;Rajini Rao;Amir Sherman;Paula Grisafi

  • A glucose transport protein expressed predominately in insulin-responsive tissues

    Maureen J. Charron;Frank C. Brosius;Seth L. Alper;Harvey F. Lodish

  • Inhibition of Ca(2+)-dependent K+ transport and cell dehydration in sickle erythrocytes by clotrimazole and other imidazole derivatives.

    C Brugnara;L de Franceschi;S L Alper

  • Subtypes of intercalated cells in rat kidney collecting duct defined by antibodies against erythroid band 3 and renal vacuolar H+-ATPase.

    S L Alper;J Natale;S Gluck;H F Lodish

  • Antigen retrieval in cryostat tissue sections and cultured cells by treatment with sodium dodecyl sulfate (SDS)

    Dennis Brown;John Lydon;Margaret McLaughlin;Alan Stuart-Tilley

  • The SLC26 gene family of anion transporters and channels.

    Seth L. Alper;Alok K. Sharma;Alok K. Sharma

  • Mutations causing medullary cystic kidney disease type 1 lie in a large VNTR in MUC1 missed by massively parallel sequencing

    Andrew Kirby;Andreas Gnirke;David B Jaffe;Veronika Barešová

  • Anion Exchanger 1 (Band 3) Is Required to Prevent Erythrocyte Membrane Surface Loss but Not to Form the Membrane Skeleton

    Luanne L Peters;Ramesh A Shivdasani;Shih-Chun Liu;Manjit Hanspal

  • Autosomal dominant tubulointerstitial kidney disease: diagnosis, classification, and management--A KDIGO consensus report.

    Kai Uwe Eckardt;Seth L. Alper;Corinne Antignac;Corinne Antignac;Anthony J. Bleyer

  • Innate immunity pathways regulate the nephropathy gene Apolipoprotein L1.

    Brendan Nichols;Prachi Jog;Jessica H. Lee;Daniel Blackler

  • Multiple clinical forms of dehydrated hereditary stomatocytosis arise from mutations in PIEZO1

    Immacolata Andolfo;Seth L. Alper;Lucia De Franceschi;Carla Auriemma

  • The Band 3-Related Anion Exchanger (AE) Gene Family

    Seth L. Alper

  • Inflammation-dependent cerebrospinal fluid hypersecretion by the choroid plexus epithelium in posthemorrhagic hydrocephalus

    Jason K Karimy;Jinwei Zhang;Jinwei Zhang;David B Kurland;Brianna Carusillo Theriault

  • Glymphatic System Impairment in Alzheimer's Disease and Idiopathic Normal Pressure Hydrocephalus.

    Benjamin C. Reeves;Jason K. Karimy;Adam J. Kundishora;Humberto Mestre

  • Therapy with oral clotrimazole induces inhibition of the Gardos channel and reduction of erythrocyte dehydration in patients with sickle cell disease.

    Carlo Brugnara;Beatrice Gee;Carrie C. Armsby;Susan Kurth

  • Molecular physiology of SLC4 anion exchangers

    Seth L. Alper

  • Molecular physiology and genetics of Na+-independent SLC4 anion exchangers.

    Seth L. Alper

  • Physiological Roles of the Intermediate Conductance, Ca2+-activated Potassium Channel Kcnn4

    Ted Begenisich;Tesuji Nakamoto;Catherine E. Ovitt;Keith Nehrke

Frequent Co-Authors

Carlo Brugnara
Carlo Brugnara Boston Children's Hospital
Martin R. Pollak
Martin R. Pollak Beth Israel Deaconess Medical Center
Wayne I. Lencer
Wayne I. Lencer Harvard University
Kristopher T. Kahle
Kristopher T. Kahle Yale University
Dennis Brown
Dennis Brown Harvard University
Achille Iolascon
Achille Iolascon University of Naples Federico II
Roberto A. Gaxiola
Roberto A. Gaxiola Arizona State University
Dandan Sun
Dandan Sun University of Pittsburgh
Richard P. Lifton
Richard P. Lifton Rockefeller University

If you think any of the details on this page are incorrect, let us know.

Report an issue

We appreciate your kind effort to assist us to improve this page, it would be helpful providing us with as much detail as possible in the text box below:

Best Scientists Citing Seth L. Alper

Trending Scientists

Recently Published Articles