James E. Melvin mainly investigates Internal medicine, Endocrinology, Cell biology, Saliva and Secretion. His Internal medicine study incorporates themes from Biophysics and In vivo. His Endocrinology study combines topics from a wide range of disciplines, such as Cell culture, Transient receptor potential channel, Glucuronate and Channel blocker.
His Cell biology research integrates issues from Acinar cell, Apical sorting and Intestinal epithelium. The Saliva study combines topics in areas such as Submandibular gland, Proteome, Parotid gland and Cell type. His study explores the link between Secretion and topics such as Salivary gland that cross with problems in Molecular cloning.
His scientific interests lie mostly in Internal medicine, Endocrinology, Cell biology, Secretion and Saliva. James E. Melvin interconnects Cotransporter, Biophysics, Parotid gland and Intracellular in the investigation of issues within Internal medicine. His research integrates issues of Extracellular, Salivary gland and Muscarinic acetylcholine receptor in his study of Endocrinology.
James E. Melvin combines subjects such as Transporter, Caenorhabditis elegans, Ion transporter and Green fluorescent protein with his study of Cell biology. In his research, Patch clamp is intimately related to Membrane potential, which falls under the overarching field of Secretion. His Saliva research incorporates themes from Proteome, Sublingual gland, Reabsorption, Proteomics and Immunology.
James E. Melvin focuses on Cell biology, Secretion, Internal medicine, Endocrinology and Saliva. His Cell biology research is multidisciplinary, incorporating elements of Cell, Transcription factor, Ion transporter, Exocrine gland and Membrane potential. The concepts of his Ion transporter study are interwoven with issues in Outer enamel epithelium and Intracellular.
His work carried out in the field of Secretion brings together such families of science as Cotransporter, Parotid gland, Molecular biology, Apical membrane and Acinar cell. His Saliva research includes elements of Potential biomarkers, Submandibular gland, Reabsorption and Proteomics, Biomarker discovery. James E. Melvin has included themes like Gene expression and Epithelial sodium channel in his Salivary gland study.
James E. Melvin spends much of his time researching Secretion, Saliva, Internal medicine, Endocrinology and Major Salivary Gland. His work is dedicated to discovering how Secretion, Parotid gland are connected with Clinical trial, Adverse effect, Molecular biology and Biopsy and other disciplines. His studies in Saliva integrate themes in fields like Submandibular gland, Acinar cell, Chloride channel and Muscarinic acetylcholine receptor.
He works on Internal medicine which deals in particular with Receptor. His research ties Cell biology and Salivary gland together. Membrane potential is closely connected to Lacrimal gland in his research, which is encompassed under the umbrella topic of Cell biology.
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The proteomes of human parotid and submandibular/sublingual gland salivas collected as the ductal secretions
Paul Denny;Fred K. Hagen;Markus Hardt;Lujian Liao.
Journal of Proteome Research (2008)
Regulation of fluid and electrolyte secretion in salivary gland acinar cells.
James E. Melvin;David Yule;Trevor Shuttleworth;Ted Begenisich.
Annual Review of Physiology (2005)
Salivary acinar cells from aquaporin 5-deficient mice have decreased membrane water permeability and altered cell volume regulation.
Carissa M. Krane;James E. Melvin;Ha Van Nguyen;Linda Richardson.
Journal of Biological Chemistry (2001)
Mouse Down-regulated in Adenoma (DRA) Is an Intestinal Cl−/HCO3 − Exchanger and Is Up-regulated in Colon of Mice Lacking the NHE3 Na+/H+Exchanger
James E. Melvin;Keerang Park;Linda Richardson;Patrick J. Schultheis.
Journal of Biological Chemistry (1999)
Proteomic Analysis of Human Parotid Gland Exosomes by Multidimensional Protein Identification Technology (MudPIT)
Mireya Gonzalez-Begne;Bingwen Lu;Xuemei Han;Fred K. Hagen.
Journal of Proteome Research (2009)
The intermediate-conductance calcium-activated potassium channel KCa3.1 contributes to atherogenesis in mice and humans
Kazuyoshi Toyama;Heike Wulff;K. George Chandy;Philippe Azam.
Journal of Clinical Investigation (2008)
A role for AQP5 in activation of TRPV4 by hypotonicity: concerted involvement of AQP5 and TRPV4 in regulation of cell volume recovery
Xibao Liu;Bidhan B. Bandyopadhyay;Tetsuji Nakamoto;Brij B. Singh.
Journal of Biological Chemistry (2006)
Physiological Roles of the Intermediate Conductance, Ca2+-activated Potassium Channel Kcnn4
Ted Begenisich;Tesuji Nakamoto;Catherine E. Ovitt;Keith Nehrke.
Journal of Biological Chemistry (2004)
Systematic comparison of the human saliva and plasma proteomes
Weihong Yan;Rolf Apweiler;Brian M Balgley;Pinmanee Boontheung.
Proteomics Clinical Applications (2009)
Severe impairment of salivation in Na+/K+/2Cl- cotransporter (NKCC1)-deficient mice.
Richard L. Evans;Keerang Park;R. James Turner;Gene E. Watson.
Journal of Biological Chemistry (2000)
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