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James E. Melvin

D-Index & Metrics

Biology and Biochemistry

D-Index
51
Citations
9172
World Ranking
17194
National Ranking
7079

James E. Melvin publication distribution in Biology and Biochemistry in 2026

The chart shows the distribution of publications by all Research.com ranked scientists in the field of Biology and Biochemistry in 2026. The highlighted bar marks where James E. Melvin sits on this spectrum.

47–56 publications: 8 scientists 57–66 publications: 35 scientists 67–76 publications: 106 scientists 77–86 publications: 231 scientists 87–96 publications: 414 scientists 97–106 publications: 546 scientists 107–116 publications: 704 scientists 117–126 publications: 849 scientists 127–136 publications: 980 scientists 137–146 publications: 942 scientists 147–156 publications: 969 scientists 157–166 publications: 950 scientists 167–176 publications: 951 scientists 177–186 publications: 915 scientists 187–196 publications: 787 scientists 197–206 publications: 841 scientists 207–216 publications: 735 scientists 217–226 publications: 709 scientists 227–236 publications: 651 scientists 237–246 publications: 605 scientists 247–256 publications: 510 scientists 257–266 publications: 524 scientists 267–276 publications: 434 scientists 277–286 publications: 418 scientists 287–296 publications: 350 scientists 297–306 publications: 363 scientists 307–316 publications: 315 scientists 317–326 publications: 296 scientists 327–336 publications: 261 scientists 337–346 publications: 240 scientists 347–356 publications: 219 scientists 357–366 publications: 197 scientists 367–376 publications: 154 scientists 377–386 publications: 161 scientists 387–396 publications: 155 scientists 397–406 publications: 145 scientists 407–416 publications: 124 scientists 417–426 publications: 112 scientists 427–436 publications: 132 scientists 437–446 publications: 116 scientists 447–456 publications: 99 scientists 457–466 publications: 81 scientists 467–476 publications: 91 scientists 477–486 publications: 80 scientists 487–496 publications: 80 scientists 497–506 publications: 60 scientists 507–516 publications: 36 scientists 517–526 publications: 46 scientists 527–536 publications: 54 scientists 537–546 publications: 44 scientists 547–556 publications: 43 scientists 557–566 publications: 43 scientists 567–576 publications: 42 scientists 577–586 publications: 25 scientists 587–596 publications: 34 scientists 597–606 publications: 23 scientists 607–616 publications: 33 scientists 617–626 publications: 31 scientists 627–636 publications: 27 scientists 637–646 publications: 25 scientists 647–656 publications: 28 scientists 657–666 publications: 34 scientists 667–676 publications: 18 scientists 677–686 publications: 16 scientists 687–696 publications: 10 scientists 697–706 publications: 12 scientists 707–716 publications: 21 scientists 717–726 publications: 12 scientists 727–736 publications: 12 scientists 737–746 publications: 10 scientists 747–756 publications: 7 scientists 757–766 publications: 13 scientists 767–776 publications: 15 scientists 777–786 publications: 13 scientists 787–796 publications: 9 scientists 797–806 publications: 9 scientists 807–816 publications: 7 scientists 817–826 publications: 4 scientists 827–836 publications: 9 scientists 837–846 publications: 7 scientists 847–856 publications: 3 scientists 857–866 publications: 5 scientists 867–876 publications: 5 scientists 877–886 publications: 11 scientists 887–896 publications: 3 scientists 897–906 publications: 4 scientists 907–916 publications: 7 scientists 917–926 publications: 5 scientists 927–936 publications: 6 scientists 937–946 publications: 6 scientists 947–956 publications: 3 scientists 957–966 publications: 7 scientists 967–976 publications: 2 scientists 977–986 publications: 2 scientists 987–996 publications: 1 scientists 997–1,006 publications: 5 scientists 1,007–1,016 publications: 2 scientists 1,017–1,026 publications: 2 scientists 1,027 publications: 1 scientists 1,028+ publications: 100 scientists
47 publications 1,028+

This scientist: 141 publications — 22nd percentile

22% of scientists in this discipline score the same or lower.

The last bar groups every scientist with 1,028 publications or more.

James E. Melvin D-index placement in Biology and Biochemistry in 2026

The chart shows the D-index (discipline H-index) distribution of Biology and Biochemistry scientists ranked by Research.com in 2026. The highlighted bar marks where James E. Melvin sits on this spectrum.

40–41 D-Index: 80 scientists 42–43 D-Index: 183 scientists 44–45 D-Index: 317 scientists 46–47 D-Index: 504 scientists 48–49 D-Index: 718 scientists 50–51 D-Index: 900 scientists 52–53 D-Index: 1,026 scientists 54–55 D-Index: 1,150 scientists 56–57 D-Index: 1,236 scientists 58–59 D-Index: 1,253 scientists 60–61 D-Index: 1,163 scientists 62–63 D-Index: 1,131 scientists 64–65 D-Index: 1,032 scientists 66–67 D-Index: 897 scientists 68–69 D-Index: 814 scientists 70–71 D-Index: 715 scientists 72–73 D-Index: 709 scientists 74–75 D-Index: 596 scientists 76–77 D-Index: 512 scientists 78–79 D-Index: 473 scientists 80–81 D-Index: 412 scientists 82–83 D-Index: 373 scientists 84–85 D-Index: 358 scientists 86–87 D-Index: 285 scientists 88–89 D-Index: 273 scientists 90–91 D-Index: 227 scientists 92–93 D-Index: 208 scientists 94–95 D-Index: 193 scientists 96–97 D-Index: 153 scientists 98–99 D-Index: 157 scientists 100–101 D-Index: 148 scientists 102–103 D-Index: 120 scientists 104–105 D-Index: 113 scientists 106–107 D-Index: 100 scientists 108–109 D-Index: 86 scientists 110–111 D-Index: 67 scientists 112–113 D-Index: 72 scientists 114–115 D-Index: 73 scientists 116–117 D-Index: 64 scientists 118–119 D-Index: 53 scientists 120–121 D-Index: 60 scientists 122–123 D-Index: 54 scientists 124–125 D-Index: 43 scientists 126–127 D-Index: 38 scientists 128–129 D-Index: 49 scientists 130–131 D-Index: 26 scientists 132–133 D-Index: 18 scientists 134–135 D-Index: 23 scientists 136–137 D-Index: 32 scientists 138–139 D-Index: 32 scientists 140–141 D-Index: 27 scientists 142–143 D-Index: 19 scientists 144–145 D-Index: 22 scientists 146–147 D-Index: 12 scientists 148–149 D-Index: 16 scientists 150–151 D-Index: 14 scientists 152–153 D-Index: 10 scientists 154–155 D-Index: 13 scientists 156–157 D-Index: 10 scientists 158–159 D-Index: 7 scientists 160–161 D-Index: 9 scientists 162–163 D-Index: 13 scientists 164–165 D-Index: 4 scientists 166 D-Index: 4 scientists 167+ D-Index: 98 scientists
40 D-Index 167+

This scientist: 51 D-Index — 14th percentile

14% of scientists in this discipline score the same or lower.

The last bar groups every scientist with 167 D-Index or more.

Overview

James E. Melvin is affiliated with the National Institutes of Health in the United States and has contributed to multiple areas within medicine, biochemistry, genetics, molecular biology, and environmental science. Their research integrates aspects of molecular biology, physiology, and cellular and molecular neuroscience, with a focus on related subfields such as oncology, global and planetary change.

The scientist's work covers several key topics, including neuropeptides and animal physiology, protein hydrolysis and bioactive peptides, peptidase inhibition and analysis, erythrocyte function and pathophysiology, S100 proteins and annexins, cell adhesion molecule research, and salivary gland disorders and functions.

Notable recent papers by James E. Melvin include:

  • Design and Synthesis of Brain Penetrant Glycopeptide Analogues of PACAP With Neuroprotective Potential for Traumatic Brain Injury and Parkinsonism (2022) published in Frontiers in Drug Discovery
  • Ano6 disruption impairs acinar cell regulatory volume decrease and protein secretion in murine submandibular salivary glands (2020) published in Journal of Cellular Physiology
  • Nkx2.3 transcription factor is a key regulator of mucous cell identity in salivary glands (2024) published in Developmental Biology
  • Antarctic Krill with parasites grow slower than uninfected peers (2025) published in Marine Biology

James E. Melvin collaborates frequently with several researchers, including:

  • Taro Mukaibo
  • Christopher R. Apostol
  • Kelsey Bernard
  • Parthasaradhireddy Tanguturi
  • G Molnár

The scientist's work has appeared across a range of publication venues reflecting interdisciplinary interests:

  • Frontiers in Drug Discovery
  • Journal of Cellular Physiology
  • Developmental Biology
  • Marine Biology

Best Publications

  • The proteomes of human parotid and submandibular/sublingual gland salivas collected as the ductal secretions

    Paul Denny;Fred K. Hagen;Markus Hardt;Lujian Liao

  • Regulation of fluid and electrolyte secretion in salivary gland acinar cells.

    James E. Melvin;David Yule;Trevor Shuttleworth;Ted Begenisich

  • Salivary acinar cells from aquaporin 5-deficient mice have decreased membrane water permeability and altered cell volume regulation.

    Carissa M. Krane;James E. Melvin;Ha Van Nguyen;Linda Richardson

  • Mouse Down-regulated in Adenoma (DRA) Is an Intestinal Cl−/HCO3 − Exchanger and Is Up-regulated in Colon of Mice Lacking the NHE3 Na+/H+Exchanger

    James E. Melvin;Keerang Park;Linda Richardson;Patrick J. Schultheis

  • Proteomic Analysis of Human Parotid Gland Exosomes by Multidimensional Protein Identification Technology (MudPIT)

    Mireya Gonzalez-Begne;Bingwen Lu;Xuemei Han;Fred K. Hagen

  • The intermediate-conductance calcium-activated potassium channel KCa3.1 contributes to atherogenesis in mice and humans

    Kazuyoshi Toyama;Heike Wulff;K. George Chandy;Philippe Azam

  • A role for AQP5 in activation of TRPV4 by hypotonicity: concerted involvement of AQP5 and TRPV4 in regulation of cell volume recovery

    Xibao Liu;Bidhan B. Bandyopadhyay;Tetsuji Nakamoto;Brij B. Singh

  • Systematic comparison of the human saliva and plasma proteomes

    Weihong Yan;Rolf Apweiler;Brian M Balgley;Pinmanee Boontheung

  • Physiological Roles of the Intermediate Conductance, Ca2+-activated Potassium Channel Kcnn4

    Ted Begenisich;Tesuji Nakamoto;Catherine E. Ovitt;Keith Nehrke

  • Tmem16A Encodes the Ca2+-activated Cl− Channel in Mouse Submandibular Salivary Gland Acinar Cells

    Victor G. Romanenko;Marcelo A. Catalán;David A. Brown;Ilva Putzier

  • Severe impairment of salivation in Na+/K+/2Cl- cotransporter (NKCC1)-deficient mice.

    Richard L. Evans;Keerang Park;R. James Turner;Gene E. Watson

  • Activation of calcium-dependent chloride channels in rat parotid acinar cells.

    J Arreola;J E Melvin;T Begenisich

  • Molecular Cloning and Functional Expression of a Rat Na+/H+ Exchanger (NHE5) Highly Expressed in Brain

    Surat Attaphitaya;Keerang Park;James E. Melvin

  • Interaction between transcellular and paracellular water transport pathways through Aquaporin 5 and the tight junction complex

    Jitesh D. Kawedia;Michelle L. Nieman;Gregory P. Boivin;James E. Melvin

  • The salivary gland fluid secretion mechanism.

    Marcelo A Catalán;Tetsuji Nakamoto;James E Melvin

  • Loss of hyperpolarization-activated Cl(-) current in salivary acinar cells from Clcn2 knockout mice.

    Keith Nehrke;Jorge Arreola;Ha-Van Nguyen;Jodi Pilato

  • Regulation of chloride channels in secretory epithelia.

    T. Begenisich;J.E. Melvin

  • Secretion and cell volume regulation by salivary acinar cells from mice lacking expression of the Clcn3 Cl- channel gene.

    Jorge Arreola;Ted Begenisich;Keith Nehrke;Ha‐Van Nguyen

  • Basolateral localization of native ClC-2 chloride channels in absorptive intestinal epithelial cells and basolateral sorting encoded by a CBS-2 domain di-leucine motif.

    Gaspar Peña-Münzenmayer;Marcelo Catalán;Isabel Cornejo;Isabel Cornejo;Carlos D. Figueroa

  • The role of HCO3- and Na+/H+ exchange in the response of rat parotid acinar cells to muscarinic stimulation.

    J E Melvin;A Moran;R J Turner

Frequent Co-Authors

Gary E. Shull
Gary E. Shull University of Cincinnati Medical Center
John R. Yates
John R. Yates Scripps Research Institute
David I. Yule
David I. Yule University of Rochester
David T.W. Wong
David T.W. Wong University of California, Los Angeles
Arthur R. Hand
Arthur R. Hand University of Connecticut
Seth L. Alper
Seth L. Alper Beth Israel Deaconess Medical Center
Indu S. Ambudkar
Indu S. Ambudkar National Institutes of Health
Carlo Brugnara
Carlo Brugnara Boston Children's Hospital
Wolfgang LiedtkeRegeneron
Wolfgang LiedtkeRegeneron Regeneron (United States)
Bruce J. Baum
Bruce J. Baum National Institutes of Health

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Best Scientists Citing James E. Melvin

David T.W. Wong

David T.W. Wong

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Publications: 50

Indu S. Ambudkar

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National Institutes of Health

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Seth L. Alper

Seth L. Alper

Beth Israel Deaconess Medical Center

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Shmuel Muallem

Shmuel Muallem

National Institutes of Health

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University of Cincinnati Medical Center

Publications: 32

Thomas J. Jentsch

Thomas J. Jentsch

Charité - University Medicine Berlin

Publications: 30

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Heike Wulff

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Publications: 30

David I. Yule

David I. Yule

University of Rochester

Publications: 29

H. Criss Hartzell

H. Criss Hartzell

Emory University

Publications: 28

Bruce J. Baum

Bruce J. Baum

National Institutes of Health

Publications: 27

Juha Kere

Juha Kere

Karolinska Institute

Publications: 25

Karl Kunzelmann

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Publications: 24

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Yasunobu Okada

Kyoto Prefectural University of Medicine

Publications: 22

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Luis J. V. Galietta

Telethon Institute Of Genetics And Medicine

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