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Wolfgang LiedtkeRegeneron

Wolfgang LiedtkeRegeneron

D-Index & Metrics

Medicine

D-Index
80
Citations
23424
World Ranking
17109
National Ranking
8571

Overview

Wolfgang LiedtkeRegeneron is a researcher affiliated with Regeneron in the United States, specializing in medical and neuroscientific fields of study. Their work spans several subfields including physiology, molecular biology, sensory systems, pulmonary and respiratory medicine, as well as neurology.

Their research primarily focuses on topics related to ion channels and receptors, erythrocyte function and pathophysiology, exercise and physiological responses, pain mechanisms and treatments, ion channel regulation and function, blood properties and coagulation, and neurobiology and insect physiology research.

Wolfgang LiedtkeRegeneron has contributed to numerous scientific publications in key venues such as bioRxiv (Cold Spring Harbor Laboratory), SSRN Electronic Journal, UNC Libraries, Proceedings of the National Academy of Sciences, and eLife.

Frequent collaborators in their research include Farshid Guilak, Yong Chen, Alireza Savadipour, Wolfgang M. Kuebler, and Robert J. Nims, highlighting a network of colleagues with overlapping research interests.

Significant recent papers authored or coauthored by LiedtkeRegeneron include:

  • Inflammatory signaling sensitizes Piezo1 mechanotransduction in articular chondrocytes as a pathogenic feed-forward mechanism in osteoarthritis, 2021, Proceedings of the National Academy of Sciences
  • TRPV4 channel opening mediates pressure-induced pancreatitis initiated by Piezo1 activation, 2020, Journal of Clinical Investigation
  • Local Peroxynitrite Impairs Endothelial Transient Receptor Potential Vanilloid 4 Channels and Elevates Blood Pressure in Obesity, 2020, Circulation
  • Epithelia-Sensory Neuron Cross Talk Underlies Cholestatic Itch Induced by Lysophosphatidylcholine, 2021, Gastroenterology
  • A synthetic mechanogenetic gene circuit for autonomous drug delivery in engineered tissues, 2021, Science Advances

Best Publications

  • Control of stem cell fate by physical interactions with the extracellular matrix.

    Farshid Guilak;Daniel M. Cohen;Bradley T. Estes;Jeffrey M. Gimble

  • Vanilloid Receptor–Related Osmotically Activated Channel (VR-OAC), a Candidate Vertebrate Osmoreceptor

    Wolfgang Liedtke;Yong Choe;Marc A. Martí-Renom;Andrea M. Bell;Andrea M. Bell

  • Role for Stearoyl-CoA Desaturase-1 in Leptin-Mediated Weight Loss

    Paul Cohen;Makoto Miyazaki;Nicholas D. Socci;Aaron Hagge-Greenberg

  • Abnormal osmotic regulation in trpv4-/- mice

    Wolfgang Liedtke;Jeffrey M. Friedman

  • GFAP Is Necessary for the Integrity of CNS White Matter Architecture and Long-Term Maintenance of Myelination

    Wolfgang Liedtke;Winfried Edelmann;Phyllis L. Bieri;Fung Chow Chiu

  • Elementary Ca2+ signals through endothelial TRPV4 channels regulate vascular function

    Swapnil K. Sonkusare;Adrian D. Bonev;Jonathan Ledoux;Jonathan Ledoux;Wolfgang Liedtke

  • TRPV4-mediated mechanotransduction regulates the metabolic response of chondrocytes to dynamic loading.

    Christopher J. O’Conor;Holly A. Leddy;Halei C. Benefield;Wolfgang B. Liedtke

  • Mutation in the mismatch repair gene Msh6 causes cancer susceptibility

    Winfried Edelmann;Kan Yang;Asad Umar;Joerg Heyer

  • Protease‐activated receptor 2 sensitizes the transient receptor potential vanilloid 4 ion channel to cause mechanical hyperalgesia in mice

    Andrew Douglas Grant;Graeme S. Cottrell;Silva Amadesi;Marcello Trevisani

  • Mammalian TRPV4 (VR-OAC) directs behavioral responses to osmotic and mechanical stimuli in Caenorhabditis elegans.

    Wolfgang Liedtke;David M. Tobin;Cornelia I. Bargmann;Jeffrey M. Friedman

  • Deletion of the transient receptor potential cation channel TRPV4 impairs murine bladder voiding

    Thomas Gevaert;Joris Vriens;Andrei Segal;Wouter Everaerts

  • TRPV4 is a regulator of adipose oxidative metabolism, inflammation and energy homeostasis

    Li Ye;Sandra Kleiner;Jun Wu;Rajan Sah

  • Transient Receptor Potential Vanilloid 4–Mediated Disruption of the Alveolar Septal Barrier A Novel Mechanism of Acute Lung Injury

    Diego F. Alvarez;Judy A. King;David Weber;Emile Addison

  • Functional characterization of TRPV4 as an osmotically sensitive ion channel in porcine articular chondrocytes

    Mimi N. Phan;Holly A. Leddy;Bartholomew J. Votta;Sanjay Kumar

  • Arterial response to shear stress critically depends on endothelial TRPV4 expression.

    Veronika Hartmannsgruber;Willm-Thomas Heyken;Michael Kacik;Anuradha Kaistha

  • Selective Role for TRPV4 Ion Channels in Visceral Sensory Pathways

    Stuart M. Brierley;Amanda J. Page;Amanda J. Page;Patrick A. Hughes;Patrick A. Hughes;Birgit Adam

  • A role for AQP5 in activation of TRPV4 by hypotonicity: concerted involvement of AQP5 and TRPV4 in regulation of cell volume recovery

    Xibao Liu;Bidhan B. Bandyopadhyay;Tetsuji Nakamoto;Brij B. Singh

  • Regulation of Pain and Itch by TRP Channels

    Carlene Moore;Rupali Gupta;Sven-Eric Jordt;Yong Chen

  • TRPV4-dependent dilation of peripheral resistance arteries influences arterial pressure.

    Scott Earley;Thierry Pauyo;Rebecca Drapp;Matthew J. Tavares

  • TRPV4 mediates pain-related behavior induced by mild hypertonic stimuli in the presence of inflammatory mediator.

    Nicole Alessandri-Haber;Elizabeth Joseph;Olayinka A. Dina;Wolfgang Liedtke

Frequent Co-Authors

Farshid Guilak
Farshid Guilak Washington University in St. Louis
Nigel W. Bunnett
Nigel W. Bunnett New York University
Jeffrey M. Friedman
Jeffrey M. Friedman Rockefeller University
Charles W. Bourque
Charles W. Bourque McGill University Health Centre
Winfried Edelmann
Winfried Edelmann Albert Einstein College of Medicine
Pierangelo Geppetti
Pierangelo Geppetti University of Florence
Mark Nelson
Mark Nelson University of Vermont
Raju Kucherlapati
Raju Kucherlapati Harvard University

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