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Neuroscience

D-Index
65
Citations
12823
World Ranking
3163
National Ranking
183

Overview

Charles W. Bourque is a researcher affiliated with the McGill University Health Centre in Canada. Their primary areas of expertise lie within the fields of neuroscience and psychology, with notable contributions across multiple specialized subfields including endocrine and autonomic systems, social psychology, cellular and molecular neuroscience, neurology, and pulmonary and respiratory medicine.

Their research has focused extensively on topics such as neuroendocrine regulation and behavior, circadian rhythm and melatonin, neuroscience of respiration and sleep, neuropharmacology, photoreceptor and optogenetics research, electrolyte and hormonal disorders, and mechanisms of neuroinflammation and neurodegeneration. These topics reflect a diverse range of interests centered on understanding complex biological systems and their regulatory pathways.

Recent scholarly output includes papers published in high-impact venues, demonstrating active engagement with the scientific community. Representative publications include:

  • Sodium regulates clock time and output via an excitatory GABAergic pathway, 2020, Nature
  • Depolarizing GABA Transmission Restrains Activity-Dependent Glutamatergic Synapse Formation in the Developing Hippocampal Circuit, 2020, Frontiers in Cellular Neuroscience
  • High dietary salt amplifies osmoresponsiveness in vasopressin-releasing neurons, 2021, Cell Reports
  • Mechanism and function of phasic firing in vasopressin-releasing magnocellular neurosecretory cells, 2021, Journal of Neuroendocrinology
  • Sex-specific differences in the circadian pattern of action potential firing by rat suprachiasmatic nucleus vasopressin neurons, 2023, Journal of Neuroendocrinology

Bourque has published regularly in journals focused on neuroendocrinology and neuroscience including the Journal of Neuroendocrinology, Nature, Cell Reports, Frontiers in Cellular Neuroscience, and the Journal of Neuroscience.

Their frequent collaborators include Zahra S. Thirouin, Joshua C. Wyrosdic, Anzala Murtaz, Claire Gizowski, and Masha Prager-Khoutorsky, indicating a collaborative approach across multiple projects and disciplines.

Best Publications

  • SPECIALIZED MEMBRANE DOMAINS FOR WATER TRANSPORT IN GLIAL CELLS : HIGH-RESOLUTION IMMUNOGOLD CYTOCHEMISTRY OF AQUAPORIN-4 IN RAT BRAIN

    Søren Nielsen;Erlend Arnulf Nagelhus;Mahmood Amiry-Moghaddam;Charles Bourque

  • Central mechanisms of osmosensation and systemic osmoregulation.

    Charles W. Bourque

  • Osmoreceptors, osmoreception, and osmoregulation.

    Charles Bourque;Stéphane Oliet;Dominique Richard

  • Mechanosensitive channels transduce osmosensitivity in supraoptic neurons

    Stéphane H. R. Oliet;Charles Bourque

  • An N-terminal variant of Trpv1 channel is required for osmosensory transduction

    Reza Sharif Naeini;Marie-France Witty;Philippe Séguéla;Charles W Bourque

  • Transient Receptor Potential Vanilloid 1 Is Required for Intrinsic Osmoreception in Organum Vasculosum Lamina Terminalis Neurons and for Normal Thirst Responses to Systemic Hyperosmolality

    Sorana Ciura;Charles W. Bourque

  • Neurons diversify astrocytes in the adult brain through sonic hedgehog signaling

    W. Todd Farmer;Therése Abrahamsson;Sabrina Chierzi;Christopher Lui

  • Clock-driven vasopressin neurotransmission mediates anticipatory thirst prior to sleep

    C. Gizowski;C. Zaelzer;C. W. Bourque

  • The neural basis of homeostatic and anticipatory thirst

    Claire Gizowski;Charles W Bourque

  • Synaptic control of rat supraoptic neurones during osmotic stimulation of the organum vasculosum lamina terminalis in vitro

    D Richard;C W Bourque

  • Transient calcium-dependent potassium current in magnocellular neurosecretory cells of the rat supraoptic nucleus.

    C W Bourque

  • NMDA receptor‐mediated rhythmic bursting activity in rat supraoptic nucleus neurones in vitro.

    Bin Hu;C. W. Bourque

  • Adult NG2-Glia Are Required for Median Eminence-Mediated Leptin Sensing and Body Weight Control

    Tina Djogo;Sarah C. Robins;Sarah Schneider;Darya Kryzskaya

  • Hypertonicity Sensing in Organum Vasculosum Lamina Terminalis Neurons: A Mechanical Process Involving TRPV1 But Not TRPV4

    Sorana Ciura;Wolfgang Liedtke;Charles W. Bourque

  • Osmometry in osmosensory neurons.

    Zizhen Zhang;Charles W Bourque

  • Osmoregulation of vasopressin neurons: a synergy of intrinsic and synaptic processes.

    Charles W. Bourque

  • Central clock excites vasopressin neurons by waking osmosensory afferents during late sleep

    Eric Trudel;Charles W Bourque

  • Calcium-dependent potassium conductance in rat supraoptic nucleus neurosecretory neurons

    C. W. Bourque;J. C. R. Randle;L. P. Renaud

  • Excitatory peptides and osmotic pressure modulate mechanosensitive cation channels in concert.

    Yassar Chakfe;Yassar Chakfe;Charles W. Bourque

  • High Salt Intake Increases Blood Pressure via BDNF-Mediated Downregulation of KCC2 and Impaired Baroreflex Inhibition of Vasopressin Neurons

    Katrina Y. Choe;Su Y. Han;Perrine Gaub;Brent Shell

  • Properties of supraoptic magnocellular neurones isolated from the adult rat.

    S. H. R. Oliet;C. W. Bourque

Frequent Co-Authors

Leo P. Renaud
Leo P. Renaud Montreal General Hospital
Keith K. Murai
Keith K. Murai McGill University Health Centre
Gareth Leng
Gareth Leng University of Edinburgh
Angel Alonso
Angel Alonso Montreal Neurological Institute and Hospital
Mike Ludwig
Mike Ludwig University of Edinburgh
Jack H. Jhamandas
Jack H. Jhamandas University of Alberta
Pierre Drapeau
Pierre Drapeau University of Montreal
Erlend A. Nagelhus
Erlend A. Nagelhus University of Oslo
Alfredo Ribeiro-da-Silva
Alfredo Ribeiro-da-Silva McGill University
P. Jesper Sjöström
P. Jesper Sjöström McGill University

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