World's Best Scientists 2026 revealed!
Erlend A. Nagelhus

Erlend A. Nagelhus

D-Index & Metrics

Neuroscience

D-Index
47
Citations
17383
World Ranking
6292
National Ranking
30

Overview

Erlend A. Nagelhus is affiliated with the University of Oslo in Norway and specializes in research across multiple domains within neuroscience and related biomedical sciences. Their work primarily addresses cellular and molecular mechanisms underlying brain function and neurological disorders.

The scientist's recent papers include:

  • Impaired glymphatic function and clearance of tau in an Alzheimer's disease model, 2020, Brain
  • LTP Induction Boosts Glutamate Spillover by Driving Withdrawal of Perisynaptic Astroglia, 2020, Neuron
  • Astrocytic Ca2+ signaling is reduced during sleep and is involved in the regulation of slow wave sleep, 2020, Nature Communications
  • Impaired astrocytic Ca2+ signaling in awake-behaving Alzheimer's disease transgenic mice, 2022, eLife
  • Optic Atrophy 1 Controls Human Neuronal Development by Preventing Aberrant Nuclear DNA Methylation, 2020, iScience

Their frequent co-authors are:

  • Wannan Tang
  • Ole Petter Ottersen
  • Vidar R. Jensen
  • Knut Sindre Åbjørsbråten
  • Rune Enger

Common publication venues for their work include:

  • Glia
  • bioRxiv (Cold Spring Harbor Laboratory)
  • Brain
  • Neuron
  • Nature Communications

The main fields of study covered by Nagelhus comprise:

  • Neuroscience
  • Medicine
  • Biochemistry, Genetics and Molecular Biology

Within these broader fields, subfields of focus include:

  • Cellular and Molecular Neuroscience
  • Molecular Biology
  • Neurology
  • Pediatrics, Perinatology and Child Health
  • Cognitive Neuroscience

The primary topics explored in their research are:

  • Neuroscience and Neuropharmacology Research
  • Neuroinflammation and Neurodegeneration Mechanisms
  • Cerebrospinal fluid and hydrocephalus
  • Fetal and Pediatric Neurological Disorders
  • Alzheimer's disease research and treatments
  • Retinal Development and Disorders
  • Traumatic Brain Injury Research

Best Publications

  • A paravascular pathway facilitates CSF flow through the brain parenchyma and the clearance of interstitial solutes, including amyloid β.

    Jeffrey J. Iliff;Minghuan Wang;Minghuan Wang;Yonghong Liao;Benjamin A. Plogg

  • SPECIALIZED MEMBRANE DOMAINS FOR WATER TRANSPORT IN GLIAL CELLS : HIGH-RESOLUTION IMMUNOGOLD CYTOCHEMISTRY OF AQUAPORIN-4 IN RAT BRAIN

    Søren Nielsen;Erlend Arnulf Nagelhus;Mahmood Amiry-Moghaddam;Charles Bourque

  • Physiological Roles of Aquaporin-4 in Brain

    Erlend A. Nagelhus;Ole P. Ottersen

  • Immunogold evidence suggests that coupling of K+ siphoning and water transport in rat retinal Müller cells is mediated by a coenrichment of Kir4.1 and AQP4 in specific membrane domains

    Erlend A. Nagelhus;Yoshiyuki Horio;Atsushi Inanobe;Akikazu Fujita

  • Aquaporin-4 in the central nervous system: Cellular and subcellular distribution and coexpression with KIR4.1

    E.A. Nagelhus;T.M. Mathiisen;O.P. Ottersen

  • Aquaporin-4 Water Channel Protein in the Rat Retina and Optic Nerve: Polarized Expression in Müller Cells and Fibrous Astrocytes

    Erlend A. Nagelhus;Margaret L. Veruki;Reidun Torp;Finn M. Haug

  • Impaired glymphatic function and clearance of tau in an Alzheimer's disease model.

    Ian F. Harrison;Ozama Ismail;Asif Machhada;Niall Colgan;Niall Colgan

  • Delayed K+ clearance associated with aquaporin-4 mislocalization: Phenotypic defects in brains of α-syntrophin-null mice

    Mahmood Amiry-Moghaddam;Anne Williamson;Maria Palomba;Tore Eid

  • Glial-conditional deletion of aquaporin-4 (Aqp4) reduces blood–brain water uptake and confers barrier function on perivascular astrocyte endfeet

    Nadia Nabil Haj-Yasein;Gry Fluge Vindedal;Martine Eilert-Olsen;Georg Andreas Gundersen

  • Aquaporins in complex tissues: distribution of aquaporins 1–5 in human and rat eye

    Steffen Hamann;Thomas Zeuthen;Morten La Cour;Erlend A. Nagelhus

  • General anesthesia selectively disrupts astrocyte calcium signaling in the awake mouse cortex

    Alexander Stanley Thrane;Alexander Stanley Thrane;Vinita Rangroo Thrane;Vinita Rangroo Thrane;Douglas Zeppenfeld;Nanhong Lou

  • Ammonia triggers neuronal disinhibition and seizures by impairing astrocyte potassium buffering

    Vinita Rangroo Thrane;Alexander S Thrane;Fushun Wang;Maria L Cotrina

  • Critical role of aquaporin-4 (AQP4) in astrocytic Ca2+ signaling events elicited by cerebral edema

    Alexander S. Thrane;Phillip M. Rappold;Takumi Fujita;Arnulfo Torres

  • Interstitial solute transport in 3D reconstructed neuropil occurs by diffusion rather than bulk flow.

    Karl Erik Holter;Karl Erik Holter;Benjamin Dam Kehlet;Benjamin Dam Kehlet;Anna Devor;Anna Devor;Terrence J. Sejnowski;Terrence J. Sejnowski

  • LTP Induction Boosts Glutamate Spillover by Driving Withdrawal of Perisynaptic Astroglia.

    Christian Henneberger;Christian Henneberger;Christian Henneberger;Lucie Bard;Aude Panatier;Aude Panatier;Aude Panatier;James P. Reynolds

  • Paravascular microcirculation facilitates rapid lipid transport and astrocyte signaling in the brain

    Vinita Rangroo Thrane;Vinita Rangroo Thrane;Alexander S. Thrane;Alexander S. Thrane;Benjamin A. Plog;Meenakshisundaram Thiyagarajan

  • Ontogeny of water transport in rat brain: postnatal expression of the aquaporin-4 water channel.

    H Wen;E A Nagelhus;E A Nagelhus;M Amiry-Moghaddam;M Amiry-Moghaddam;P Agre;P Agre

  • Astrocytic Ca2+ signaling is reduced during sleep and is involved in the regulation of slow wave sleep

    Laura Bojarskaite;Daniel Marelius Bjørnstad;Klas Pettersen;Celine Cunen

  • Aquaporin-4 and epilepsy.

    Devin K. Binder;Erlend A. Nagelhus;Ole Petter Ottersen

  • Dynamics of Ionic Shifts in Cortical Spreading Depression

    Rune Enger;Wannan Tang;Gry Fluge Vindedal;Vidar Jensen

  • Evidence that compromised K+ spatial buffering contributes to the epileptogenic effect of mutations in the human kir4.1 gene (KCNJ10)

    Nadia Nabil Haj-Yasein;Vidar Jensen;Gry Fluge Vindedal;Georg Andreas Gundersen

Frequent Co-Authors

Ole Petter Ottersen
Ole Petter Ottersen University of Oslo
Vidar Jensen
Vidar Jensen University of Oslo
Christian Henneberger
Christian Henneberger University of Bonn
Erik Taubøll
Erik Taubøll Oslo University Hospital
U. Valentin Nägerl
U. Valentin Nägerl University of Bordeaux
Michael G. Stewart
Michael G. Stewart The Open University
Dmitri A. Rusakov
Dmitri A. Rusakov University College London
Leif Gjerstad
Leif Gjerstad Oslo University Hospital
Sigbjørn Lien
Sigbjørn Lien Norwegian University of Life Sciences

If you think any of the details on this page are incorrect, let us know.

Report an issue

We appreciate your kind effort to assist us to improve this page, it would be helpful providing us with as much detail as possible in the text box below:

Best Scientists Citing Erlend A. Nagelhus

Trending Scientists