Erlend A. Nagelhus mostly deals with Aquaporin 4, Cell biology, Neuroscience, Aquaporin and Astrocyte. His Aquaporin 4 research incorporates elements of Blood–brain barrier, Immunology, Molecular biology, Barrier function and Knockout mouse. His research in Cell biology intersects with topics in Osmotic concentration, Osmotic shock and Edema.
In his study, Potassium channel, Interstitial fluid, Biophysics and Epilepsy is strongly linked to Extracellular, which falls under the umbrella field of Neuroscience. His Aquaporin research incorporates themes from Neuropil, Immunogold labelling, Retina and Neuroglia. His Astrocyte research integrates issues from Cellular neuroscience, Inhibitory postsynaptic potential, Ataxia, Depolarization and Hyperammonemia.
His scientific interests lie mostly in Aquaporin 4, Neuroscience, Cell biology, Pathology and Immunogold labelling. His Aquaporin 4 research includes elements of Biophysics, Glymphatic system, Cerebrospinal fluid and Blood–brain barrier. The study incorporates disciplines such as Extracellular and Glutamate receptor in addition to Neuroscience.
His work on Aquaporin as part of general Cell biology research is frequently linked to Water transport and Syntrophin, bridging the gap between disciplines. His Pathology research incorporates elements of Astrogliosis and Intracranial pressure. Erlend A. Nagelhus works mostly in the field of Immunogold labelling, limiting it down to topics relating to Membrane and, in certain cases, Ependymal Cell.
Erlend A. Nagelhus spends much of his time researching Aquaporin 4, Neuroscience, Pathology, Glutamate receptor and Glymphatic system. His work deals with themes such as Effective diffusion coefficient, Biophysics and Inositol, which intersect with Aquaporin 4. His work carried out in the field of Pathology brings together such families of science as Astrogliosis and Intracranial pressure.
His studies in Glutamate receptor integrate themes in fields like Astrocyte, Excitatory postsynaptic potential, Hippocampal formation, Long-term potentiation and Cell biology. His study in the field of Ca2 signaling is also linked to topics like Two-photon excitation microscopy. The concepts of his Glymphatic system study are interwoven with issues in Extracellular fluid and Interstitial fluid.
Erlend A. Nagelhus focuses on Neuroscience, Aquaporin 4, Calcium signaling, Pathology and Parenchyma. Erlend A. Nagelhus conducts interdisciplinary study in the fields of Neuroscience and Whisking in animals through his research. Erlend A. Nagelhus has included themes like Glymphatic system, Cerebral blood flow and Amyloid in his Aquaporin 4 study.
His work is connected to Dementia, Neurodegeneration, Cerebrospinal fluid and Immunogold labelling, as a part of Pathology. His studies deal with areas such as Immunohistochemistry, Ependymal Cell, Cerebral cortex and Membrane, Cell membrane as well as Parenchyma. His study in Membrane is interdisciplinary in nature, drawing from both Extracellular fluid, Interstitial space and Interstitial fluid.
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A paravascular pathway facilitates CSF flow through the brain parenchyma and the clearance of interstitial solutes, including amyloid β.
Jeffrey J. Iliff;Minghuan Wang;Minghuan Wang;Yonghong Liao;Benjamin A. Plogg.
Science Translational Medicine (2012)
SPECIALIZED MEMBRANE DOMAINS FOR WATER TRANSPORT IN GLIAL CELLS : HIGH-RESOLUTION IMMUNOGOLD CYTOCHEMISTRY OF AQUAPORIN-4 IN RAT BRAIN
Søren Nielsen;Erlend Arnulf Nagelhus;Mahmood Amiry-Moghaddam;Charles Bourque.
The Journal of Neuroscience (1997)
Immunogold evidence suggests that coupling of K+ siphoning and water transport in rat retinal Müller cells is mediated by a coenrichment of Kir4.1 and AQP4 in specific membrane domains
Erlend A. Nagelhus;Yoshiyuki Horio;Atsushi Inanobe;Akikazu Fujita.
Glia (1999)
Aquaporin-4 in the central nervous system: Cellular and subcellular distribution and coexpression with KIR4.1
E.A. Nagelhus;T.M. Mathiisen;O.P. Ottersen.
Neuroscience (2004)
Aquaporin-4 Water Channel Protein in the Rat Retina and Optic Nerve: Polarized Expression in Müller Cells and Fibrous Astrocytes
Erlend A. Nagelhus;Margaret L. Veruki;Reidun Torp;Finn M. Haug.
The Journal of Neuroscience (1998)
Physiological Roles of Aquaporin-4 in Brain
Erlend A. Nagelhus;Ole P. Ottersen.
Physiological Reviews (2013)
Delayed K+ clearance associated with aquaporin-4 mislocalization: Phenotypic defects in brains of α-syntrophin-null mice
Mahmood Amiry-Moghaddam;Anne Williamson;Maria Palomba;Tore Eid.
Proceedings of the National Academy of Sciences of the United States of America (2003)
Aquaporins in complex tissues: distribution of aquaporins 1–5 in human and rat eye
Steffen Hamann;Thomas Zeuthen;Morten La Cour;Erlend A. Nagelhus.
American Journal of Physiology-cell Physiology (1998)
Critical role of aquaporin-4 (AQP4) in astrocytic Ca2+ signaling events elicited by cerebral edema
Alexander S. Thrane;Phillip M. Rappold;Takumi Fujita;Arnulfo Torres.
Proceedings of the National Academy of Sciences of the United States of America (2011)
Glial-conditional deletion of aquaporin-4 (Aqp4) reduces blood–brain water uptake and confers barrier function on perivascular astrocyte endfeet
Nadia Nabil Haj-Yasein;Gry Fluge Vindedal;Martine Eilert-Olsen;Georg Andreas Gundersen.
Proceedings of the National Academy of Sciences of the United States of America (2011)
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