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D-Index & Metrics

Biology and Biochemistry

D-Index
93
Citations
36040
World Ranking
2080
National Ranking
145

Overview

Hartwig Wolburg is affiliated with the University of Tübingen in Germany and has contributed to research primarily in the fields of neuroscience and biochemistry, genetics, and molecular biology. Their work focuses on the structural and functional aspects of biological barriers, neuronal disease mechanisms, and molecular interactions within cellular environments.

The main fields of study represented in their publications include:

  • Neuroscience
  • Biochemistry, Genetics and Molecular Biology

Subfields of research encompass:

  • Neurology
  • Molecular Biology
  • Immunology and Allergy
  • Cell Biology
  • Cancer Research

The key research topics Hartwig Wolburg has addressed are:

  • Barrier Structure and Function Studies
  • Neurological Disease Mechanisms and Treatments
  • Cell Adhesion Molecules Research
  • Connexins and lens biology
  • Angiogenesis and VEGF in Cancer
  • Caveolin-1 and cellular processes
  • Cancer-related molecular mechanisms research

Hartwig Wolburg has published several papers demonstrating their engagement with these areas. Selected recent publications include:

  • "Tight junctions in the blood-brain barrier promote edema formation and infarct size in stroke - Ambivalent effects of sealing proteins", 2020, Journal of Cerebral Blood Flow & Metabolism
  • "Mural Cell SRF Controls Pericyte Migration, Vessel Patterning and Blood Flow", 2022, Circulation Research
  • "M01 as a novel drug enhancer for specifically targeting the blood-brain barrier.", 2021, Journal of Controlled Release
  • "Mural cell SRF controls pericyte migration, vessel patterning and blood flow", 2021, bioRxiv (Cold Spring Harbor Laboratory)
  • "Gαi2 Signaling Regulates Neonatal Respiratory Adaptation", 2025, International Journal of Molecular Sciences

The diversity of publication venues reflects interdisciplinary collaboration and research dissemination across neuroscience, molecular biology, and clinical studies. Frequent publication venues include:

  • Journal of Cerebral Blood Flow & Metabolism
  • Circulation Research
  • Journal of Controlled Release
  • bioRxiv (Cold Spring Harbor Laboratory)
  • International Journal of Molecular Sciences

Collaboration is evident through repeated coauthorship with several researchers, indicating ongoing research partnerships. Frequent coauthors include:

  • Lars Winkler
  • Olga Breitkreuz-Korff
  • Sophie Dithmer
  • Ingolf E. Blasig
  • Reiner F. Haseloff

Best Publications

  • Distinct roles of the receptor tyrosine kinases Tie-1 and Tie-2 in blood vessel formation

    Thomas N. Sato;Yuzuru Tozawa;Urban Deutsch;Karen Wolburg-Buchholz

  • Tight junctions of the blood-brain barrier: development, composition and regulation.

    Hartwig Wolburg;Andrea Lippoldt;Andrea Lippoldt

  • Lack of pericytes leads to endothelial hyperplasia and abnormal vascular morphogenesis.

    Mats Hellström;Holger Gerhardt;Holger Gerhardt;Mattias Kalén;Xuri Li

  • Aβ42‐driven cerebral amyloidosis in transgenic mice reveals early and robust pathology

    Rebecca Radde;Tristan Bolmont;Stephan A Kaeser;Janaky Coomaraswamy

  • Wnt/β-catenin signaling controls development of the blood–brain barrier

    Stefan Liebner;Monica Corada;Thorsten Bangsow;Jane Babbage

  • Vascular endothelial growth factor induces endothelial fenestrations in vitro.

    Sybille Esser;Karen Wolburg;Hartwig Wolburg;Georg Breier

  • Development of the blood-brain barrier.

    Werner Risau;Hartwig Wolburg

  • Loss of function mutations in the gene encoding Omi/HtrA2 in Parkinson's disease

    Karsten M. Strauss;L. Miguel Martins;Helene Plun-Favreau;Frank P. Marx

  • Viscoelastic properties of individual glial cells and neurons in the CNS

    Yun-Bi Lu;Kristian Franze;Gerald Seifert;Christian Steinhäuser

  • Peripherally Applied Aβ-Containing Inoculates Induce Cerebral β-Amyloidosis

    Yvonne S. Eisele;Ulrike Obermüller;Ulrike Obermüller;Götz Heilbronner;Götz Heilbronner;Frank Baumann;Frank Baumann

  • Formation and maintenance of Alzheimer’s disease beta-amyloid plaques in the absence of microglia

    Stefan Grathwohl;R.E. Kälin;T. Bolmont;S. Prokop

  • Localization of claudin-3 in tight junctions of the blood-brain barrier is selectively lost during experimental autoimmune encephalomyelitis and human glioblastoma multiforme

    Hartwig Wolburg;Karen Wolburg-Buchholz;Karen Wolburg-Buchholz;Jörg Kraus;Gesa Rascher-Eggstein

  • Claudin-1 and claudin-5 expression and tight junction morphology are altered in blood vessels of human glioblastoma multiforme

    S Liebner;A Fischmann;G Rascher;F Duffner

  • Brain endothelial cells and the glio-vascular complex

    Hartwig Wolburg;Susan Noell;Andreas Mack;Karen Wolburg-Buchholz

  • Modulation of tight junction structure in blood-brain barrier endothelial cells. Effects of tissue culture, second messengers and cocultured astrocytes

    H. Wolburg;J. Neuhaus;U. Kniesel;B. Krauss

  • Formation of tight junction: determinants of homophilic interaction between classic claudins

    Jörg Piontek;Lars Winkler;Hartwig Wolburg;Sebastian L. Müller

  • Mini-review: Transendothelial migration of leukocytes: through the front door or around the side of the house?

    Britta Engelhardt;Hartwig Wolburg

  • Choroid plexus: biology and pathology

    Hartwig Wolburg;Werner Paulus

  • Reduced basal autophagy and impaired mitochondrial dynamics due to loss of Parkinson's disease-associated protein DJ-1.

    Guido Krebiehl;Sabine Ruckerbauer;Lena F. Burbulla;Nicole Kieper

  • Molecular outcomes of neuromyelitis optica (NMO)-IgG binding to aquaporin-4 in astrocytes

    Shannon R. Hinson;Michael F. Romero;Bogdan F. Gh. Popescu;Claudia F. Lucchinetti

Frequent Co-Authors

Andreas Reichenbach
Andreas Reichenbach Leipzig University
Holger Gerhardt
Holger Gerhardt Max Delbrück Center for Molecular Medicine
Britta Engelhardt
Britta Engelhardt University of Bern
Ingolf E. Blasig
Ingolf E. Blasig Leibniz Institute for Neurobiology
Dietmar Vestweber
Dietmar Vestweber Max Planck Society
Olaf Riess
Olaf Riess University of Tübingen
Urban Deutsch
Urban Deutsch University of Bern
Werner Risau
Werner Risau Max Planck Society
Rejko Krüger
Rejko Krüger University of Luxembourg
Paul M. Mathews
Paul M. Mathews New York University

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