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Biology and Biochemistry

D-Index
56
Citations
13364
World Ranking
14288
National Ranking
22

Overview

Mária A. Deli is affiliated with the Biological Research Centre in Hungary. Their research primarily focuses on the study of blood-brain barrier (BBB) dynamics and associated molecular and cellular mechanisms. The scientist's work contributes to understanding the complex interplay of physical and biochemical factors that influence BBB function and drug delivery systems targeting the central nervous system.

The main fields of study for Mária A. Deli include Medicine, Biochemistry, Genetics and Molecular Biology, and Neuroscience. These disciplines support their investigations into the biological and physiological processes underlying barrier integrity, molecular transport, and neurological disease mechanisms.

The scientist's subfields of study highlight a detailed focus on Molecular Biology, Neurology, Cellular and Molecular Neuroscience, Biomedical Engineering, and Pharmaceutical Science. These areas reflect their interdisciplinary approach combining basic biological research with applied pharmaceutical strategies.

Mária A. Deli's research covers multiple topics related to barrier structure and function, drug transport, and neurological diseases. The key topics of their work include:

  • Barrier Structure and Function Studies
  • Drug Transport and Resistance Mechanisms
  • Advanced Drug Delivery Systems
  • Nanoparticle-Based Drug Delivery
  • Neurological Disease Mechanisms and Treatments
  • Lipid Membrane Structure and Behavior
  • Neuroinflammation and Neurodegeneration Mechanisms

Among their recent published papers are studies that focus on blood-brain barrier properties and drug transport mechanisms:

  • "Transendothelial Electrical Resistance Measurement across the Blood-Brain Barrier: A Critical Review of Methods," 2021, Micromachines
  • "ApoE-Targeting Increases the Transfer of Solid Lipid Nanoparticles with Donepezil Cargo across a Culture Model of the Blood-Brain Barrier," 2020, Pharmaceutics
  • "Surface charge, glycocalyx, and blood-brain barrier function," 2021, Tissue Barriers
  • "Flow induces barrier and glycocalyx-related genes and negative surface charge in a lab-on-a-chip human blood-brain barrier model," 2021, Journal of Cerebral Blood Flow & Metabolism
  • "Glycocalyx regulates the strength and kinetics of cancer cell adhesion revealed by biophysical models based on high resolution label-free optical data," 2020, Scientific Reports

Mária A. Deli frequently collaborates with several researchers, indicating a networked approach to scientific investigation. Notable frequent co-authors include:

  • Fruzsina R. Walter
  • Ana Raquel Santa-Maria
  • Szilvia Veszelka
  • Mária Mészáros
  • Ilona Gróf

The scientist often publishes in journals that focus on pharmacology, neuroscience, and barrier research. Some of the most frequent publication venues are:

  • Pharmaceutics
  • Fluids and Barriers of the CNS
  • International Journal of Molecular Sciences
  • bioRxiv (Cold Spring Harbor Laboratory)
  • International Journal of Pharmaceutics

Best Publications

  • A new blood–brain barrier model using primary rat brain endothelial cells, pericytes and astrocytes

    Shinsuke Nakagawa;Mária A. Deli;Hiroko Kawaguchi;Takeshi Shimizudani

  • In vitro models of the blood-brain barrier: An overview of commonly used brain endothelial cell culture models and guidelines for their use

    Hans C. Helms;N. Joan Abbott;Malgorzata Burek;Romeo Cecchelli

  • Detection and isolation of cell-derived microparticles are compromised by protein complexes resulting from shared biophysical parameters

    Bence György;Károly Módos;Éva Pállinger;Krisztina Pálóczi

  • Pericytes from brain microvessels strengthen the barrier integrity in primary cultures of rat brain endothelial cells.

    Shinsuke Nakagawa;Mária A. Deli;Mária A. Deli;Shinobu Nakao;Masaru Honda

  • Potential use of tight junction modulators to reversibly open membranous barriers and improve drug delivery

    Mária A. Deli

  • Puromycin-based purification of rat brain capillary endothelial cell cultures. Effect on the expression of blood-brain barrier-specific properties.

    N Perriere;PH Demeuse;E Garcia;A Regina

  • Antibiotic-resistant bacteria show widespread collateral sensitivity to antimicrobial peptides

    Viktória Lázár;Viktória Lázár;Ana Martins;Réka Spohn;Lejla Daruka

  • HIV‐1 Tat protein alters tight junction protein expression and distribution in cultured brain endothelial cells

    Ibolya E. András;Hong Pu;Mária A. Deli;Avindra Nath

  • Comparison of brain capillary endothelial cell-based and epithelial (MDCK-MDR1, Caco-2, and VB-Caco-2) cell-based surrogate blood-brain barrier penetration models

    Éva Hellinger;Szilvia Veszelka;Andrea E. Tóth;Fruzsina Walter

  • Exposure of tumor necrosis factor-alpha to luminal membrane of bovine brain capillary endothelial cells cocultured with astrocytes induces a delayed increase of permeability and cytoplasmic stress fiber formation of actin.

    M A Deli;L Descamps;M P Dehouck;R Cecchelli

  • A functional in vitro model of rat blood-brain barrier for molecular analysis of efflux transporters.

    Nicolas Perrière;Salah Yousif;Sylvie Cazaubon;Nathalie Chaverot

  • Role of the blood-brain barrier in the nutrition of the central nervous system.

    Patricia Campos-Bedolla;Fruzsina R. Walter;Szilvia Veszelka;Mária A. Deli

  • Evaluation of cytotoxicity of surfactants used in self-micro emulsifying drug delivery systems and their effects on paracellular transport in Caco-2 cell monolayer.

    Zoltán Ujhelyi;Ferenc Fenyvesi;Judit Váradi;Pálma Fehér

  • Intracellular transport of Toxoplasma gondii through the blood-brain barrier.

    Sabrina M. Lachenmaier;Mária A. Deli;Markus Meissner;Oliver Liesenfeld

  • Experimental acute pancreatitis results in increased blood–brain barrier permeability in the rat: a potential role for tumor necrosis factor and interleukin 6

    Gyula Farkas;János Márton;Zsuzsanna Nagy;Yvette Mándi

  • The NMDA and AMPA/KA receptors are involved in glutamate-induced alterations of occludin expression and phosphorylation in brain endothelial cells.

    Ibolya E András;Mária A Deli;Szilvia Veszelka;Kentaro Hayashi

  • A versatile lab-on-a-chip tool for modeling biological barriers

    Fruzsina Walter;Sándor Valkai;András Kincses;András Petneházi

  • Expression of Glutamate Receptors on Cultured Cerebral Endothelial Cells

    István A. Krizbai;Mária A. Deli;Anikó Pestenácz;László Siklós

  • Signaling mechanisms of HIV-1 Tat-induced alterations of claudin-5 expression in brain endothelial cells.

    Ibolya E András;Hong Pu;Jing Tian;Mária A Deli

  • Kinetic analysis of the toxicity of pharmaceutical excipients cremophor EL and RH40 on endothelial and epithelial cells

    Lóránd Kiss;Fruzsina R. Walter;Alexandra Bocsik;Alexandra Bocsik;Szilvia Veszelka

Frequent Co-Authors

Masami Niwa
Masami Niwa Nagasaki University
Ferenc Joó
Ferenc Joó University of Debrecen
Piroska Szabó-Révész
Piroska Szabó-Révész University of Szeged
Gábor Rákhely
Gábor Rákhely University of Szeged
András Falus
András Falus Semmelweis University
Yoichi Ueta
Yoichi Ueta University of Occupational and Environmental Health Japan
Roméo Cecchelli
Roméo Cecchelli Artois University
Gérard Torpier
Gérard Torpier Institut Pasteur
László Vécsei
László Vécsei University of Szeged
Edit I. Buzás
Edit I. Buzás Semmelweis University

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