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D-Index & Metrics

Biology and Biochemistry

D-Index
56
Citations
13939
World Ranking
14265
National Ranking
6015

Research.com Recognitions

  • 2014 - Fellow of the Indian National Academy of Engineering (INAE)

Overview

Eric V. Shusta is affiliated with the University of Wisconsin-Madison in the United States. Their research spans across several fields, primarily focusing on Biochemistry, Genetics and Molecular Biology, Neuroscience, and Medicine.

The main subfields of study for this researcher include Molecular Biology, Neurology, Cancer Research, Radiology, Nuclear Medicine and Imaging, and Immunology. Their work covers key topics such as Barrier Structure and Function Studies, Monoclonal and Polyclonal Antibodies Research, Pluripotent Stem Cells Research, Single-cell and spatial transcriptomics, Neuroinflammation and Neurodegeneration Mechanisms, MicroRNA in disease regulation, and Cancer-related molecular mechanisms research.

Frequent co-authors collaborating with Eric V. Shusta include:

  • Sean P. Palecek
  • Benjamin D. Gastfriend
  • Koji L. Foreman
  • Moriah E. Katt
  • Britta Engelhardt

The most common publication venues are:

  • Pharmaceutics
  • bioRxiv (Cold Spring Harbor Laboratory)
  • Methods in molecular biology
  • Scientific Reports
  • Fluids and Barriers of the CNS

Recent notable papers include:

  • Neuronal Activity Regulates Blood-Brain Barrier Efflux Transport through Endothelial Circadian Genes, 2020, Neuron
  • Transcriptomic comparison of human and mouse brain microvessels, 2020, Scientific Reports
  • A human three-dimensional neural-perivascular 'assembloid' promotes astrocytic development and enables modeling of SARS-CoV-2 neuropathology, 2021, Nature Medicine
  • Commentary on human pluripotent stem cell-based blood-brain barrier models, 2020, Fluids and Barriers of the CNS
  • Intrinsic blood-brain barrier dysfunction contributes to multiple sclerosis pathogenesis, 2022, Brain

Eric V. Shusta has been recognized with the award of Fellow of the Indian National Academy of Engineering (INAE) in 2014.

Best Publications

  • Derivation of blood-brain barrier endothelial cells from human pluripotent stem cells

    Ethan S Lippmann;Samira M Azarin;Jennifer E Kay;Randy A Nessler

  • In vitro models of the blood-brain barrier: An overview of commonly used brain endothelial cell culture models and guidelines for their use

    Hans C. Helms;N. Joan Abbott;Malgorzata Burek;Romeo Cecchelli

  • Blood-Brain Barrier Transport of Therapeutics via Receptor- Mediation

    Angela R. Jones;Eric V. Shusta

  • Strategies to advance translational research into brain barriers

    Edward Neuwelt;N Joan Abbott;Lauren Abrey;William A Banks

  • A retinoic acid-enhanced, multicellular human blood-brain barrier model derived from stem cell sources

    Ethan S. Lippmann;Abraham Al-Ahmad;Samira M. Azarin;Sean P. Palecek

  • Hypoxia-enhanced Blood-Brain Barrier Chip recapitulates human barrier function and shuttling of drugs and antibodies.

    Tae-Eun Park;Nur Mustafaoglu;Anna Herland;Anna Herland;Anna Herland;Ryan Hasselkus

  • In vitro evolution of a T cell receptor with high affinity for peptide/MHC

    Phillip D. Holler;Philmore O. Holman;Eric V. Shusta;Sean O'Herrin

  • Targeting Receptor-Mediated Transport for Delivery of Biologics Across the Blood-Brain Barrier

    Jason M. Lajoie;Eric V. Shusta

  • Yeast cell surface display of proteins and uses thereof

    Dane K. Wittrup;Michele C. Kieke;David M. Kranz;Eric Shusta

  • Increasing the secretory capacity of Saccharomyces cerevisiae for production of single-chain antibody fragments

    E V Shusta;R T Raines;A Plückthun;K D Wittrup

  • Efficient Differentiation of Human Pluripotent Stem Cells to Endothelial Progenitors via Small-Molecule Activation of WNT Signaling

    Xiaojun Lian;Xiaoping Bao;Abraham Al-Ahmad;Jialu Liu

  • Directed evolution of a stable scaffold for T-cell receptor engineering

    E V Shusta;P D Holler;M C Kieke;D M Kranz

  • Yeast polypeptide fusion surface display levels predict thermal stability and soluble secretion efficiency.

    Eric V Shusta;Michele C Kieke;Evan Parke;David M Kranz

  • Selection of functional T cell receptor mutants from a yeast surface-display library.

    Michele C. Kieke;Eric V. Shusta;Eric T. Boder;Luc Teyton

  • A decade of yeast surface display technology: where are we now?

    Lauren R. Pepper;Yong Ku Cho;Eric T. Boder;Eric V. Shusta

  • An isogenic blood-brain barrier model comprising brain endothelial cells, astrocytes, and neurons derived from human induced pluripotent stem cells.

    Scott G. Canfield;Matthew J. Stebbins;Bethsymarie Soto Morales;Shusaku W. Asai

  • Modeling Psychomotor Retardation using iPSCs from MCT8-Deficient Patients Indicates a Prominent Role for the Blood-Brain Barrier

    Gad D. Vatine;Abraham Al-Ahmad;Abraham Al-Ahmad;Bianca K. Barriga;Soshana Svendsen

  • Directed differentiation of human pluripotent stem cells to blood-brain barrier endothelial cells.

    Tongcheng Qian;Shaenah E. Maguire;Scott G. Canfield;Xiaoping Bao

  • Puromycin‐purified rat brain microvascular endothelial cell cultures exhibit improved barrier properties in response to glucocorticoid induction

    Anthony R Calabria;Christian Weidenfeller;Angela R Jones;Helga E de Vries

  • Human pluripotent stem cell-derived brain pericyte-like cells induce blood-brain barrier properties.

    Matthew J. Stebbins;Benjamin D. Gastfriend;Scott G. Canfield;Ming-Song Lee

Frequent Co-Authors

Sean P. Palecek
Sean P. Palecek University of Wisconsin–Madison
David M. Kranz
David M. Kranz University of Illinois at Urbana-Champaign
Donald E. Ingber
Donald E. Ingber Harvard University
Clive N. Svendsen
Clive N. Svendsen Cedars-Sinai Medical Center
William M. Pardridge
William M. Pardridge University of California, Los Angeles
Ruben J. Boado
Ruben J. Boado University of California, Los Angeles
Kelly S. Doran
Kelly S. Doran University of Colorado Denver
Nicholas L. Abbott
Nicholas L. Abbott Cornell University

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