D-Index & Metrics Best Publications

D-Index & Metrics D-index (Discipline H-index) only includes papers and citation values for an examined discipline in contrast to General H-index which accounts for publications across all disciplines.

Discipline name D-index D-index (Discipline H-index) only includes papers and citation values for an examined discipline in contrast to General H-index which accounts for publications across all disciplines. Citations Publications World Ranking National Ranking
Biology and Biochemistry D-index 65 Citations 17,444 181 World Ranking 4105 National Ranking 2056

Research.com Recognitions

Awards & Achievements

2014 - Fellow of the Indian National Academy of Engineering (INAE)

Overview

What is he best known for?

The fields of study he is best known for:

  • Gene
  • Enzyme
  • DNA

Sean P. Palecek spends much of his time researching Cell biology, Embryonic stem cell, Induced pluripotent stem cell, Cellular differentiation and Extracellular matrix. He specializes in Cell biology, namely Stem cell. His Embryonic stem cell study incorporates themes from Immunology, Molecular biology and Matrigel.

His Induced pluripotent stem cell research is multidisciplinary, incorporating elements of SOX2, Internal medicine, Monocarboxylate transporter and Blood–brain barrier. His Cellular differentiation study integrates concerns from other disciplines, such as Endothelial stem cell, Wnt signaling pathway, Activin type 2 receptors, NODAL and Flow cytometry. His Extracellular matrix research incorporates elements of Mechanotransduction, Cell migration and Cell type.

His most cited work include:

  • Integrin-ligand binding properties govern cell migration speed through cell-substratum adhesiveness (1232 citations)
  • Functional Cardiomyocytes Derived From Human Induced Pluripotent Stem Cells (1103 citations)
  • Robust cardiomyocyte differentiation from human pluripotent stem cells via temporal modulation of canonical Wnt signaling (1002 citations)

What are the main themes of his work throughout his whole career to date?

Sean P. Palecek mainly investigates Cell biology, Induced pluripotent stem cell, Embryonic stem cell, Stem cell and Cellular differentiation. His biological study spans a wide range of topics, including Endothelial stem cell, Cell culture and Cell. His Cell culture study combines topics in areas such as Biotechnology and Nanotechnology.

Sean P. Palecek has included themes like In vitro, Regenerative medicine, Cell type and Blood–brain barrier in his Induced pluripotent stem cell study. His Embryonic stem cell study which covers Extracellular matrix that intersects with Biophysics. His research in Cellular differentiation intersects with topics in Flow cytometry, Immunology, Keratinocyte, Directed differentiation and Cell fate determination.

He most often published in these fields:

  • Cell biology (62.44%)
  • Induced pluripotent stem cell (38.91%)
  • Embryonic stem cell (34.39%)

What were the highlights of his more recent work (between 2018-2021)?

  • Induced pluripotent stem cell (38.91%)
  • Cell biology (62.44%)
  • Blood–brain barrier (12.67%)

In recent papers he was focusing on the following fields of study:

His primary areas of study are Induced pluripotent stem cell, Cell biology, Blood–brain barrier, Pericyte and Cell. Sean P. Palecek has researched Induced pluripotent stem cell in several fields, including Progenitor cell, Phenotype, Computational biology and Cellular differentiation. His work in Cellular differentiation tackles topics such as Gene expression which are related to areas like Sarcomere organization.

His studies in Cell biology integrate themes in fields like In vitro, Transcriptome, Neural crest, Morphogenesis and Cell type. The concepts of his Blood–brain barrier study are interwoven with issues in Human Induced Pluripotent Stem Cells, Neurovascular bundle, Stem cell and Tight junction. His research integrates issues of Embryonic stem cell and Flow cytometry in his study of Forebrain.

Between 2018 and 2021, his most popular works were:

  • Hypoxia-enhanced Blood-Brain Barrier Chip recapitulates human barrier function and shuttling of drugs and antibodies. (120 citations)
  • Human pluripotent stem cell–derived brain pericyte–like cells induce blood-brain barrier properties (53 citations)
  • An isogenic neurovascular unit model comprised of human induced pluripotent stem cell-derived brain microvascular endothelial cells, pericytes, astrocytes, and neurons (31 citations)

In his most recent research, the most cited papers focused on:

  • Gene
  • Enzyme
  • DNA

His scientific interests lie mostly in Induced pluripotent stem cell, Cell biology, Blood–brain barrier, Barrier function and Human brain. His work in Induced pluripotent stem cell addresses issues such as Progenitor cell, which are connected to fields such as Neuroscience, Calcium signaling, Mesoderm, Wnt signaling pathway and Directed differentiation. His Cell biology research integrates issues from Pericyte, Ion channel, Cellular differentiation and In vivo.

He interconnects Human Induced Pluripotent Stem Cells, Neurovascular bundle, Stem cell and Astrocyte in the investigation of issues within Blood–brain barrier. His Stem cell research is multidisciplinary, incorporating perspectives in Embryonic stem cell, Forebrain and Neural crest. His Barrier function study incorporates themes from Extracellular matrix component, Endothelium, Tight junction and CD44.

This overview was generated by a machine learning system which analysed the scientist’s body of work. If you have any feedback, you can contact us here.

Best Publications

Integrin-ligand binding properties govern cell migration speed through cell-substratum adhesiveness

Sean P. Palecek;Joseph C. Loftus;Mark H. Ginsberg;Douglas A. Lauffenburger.
Nature (1997)

1637 Citations

Functional Cardiomyocytes Derived From Human Induced Pluripotent Stem Cells

Jianhua Zhang;Gisela F. Wilson;Andrew G. Soerens;Chad H. Koonce.
Circulation Research (2009)

1471 Citations

Robust cardiomyocyte differentiation from human pluripotent stem cells via temporal modulation of canonical Wnt signaling

Xiaojun Lian;Cheston Hsiao;Gisela Wilson;Kexian Zhu.
Proceedings of the National Academy of Sciences of the United States of America (2012)

1232 Citations

Directed cardiomyocyte differentiation from human pluripotent stem cells by modulating Wnt/β-catenin signaling under fully defined conditions

Xiaojun Lian;Jianhua Zhang;Samira M Azarin;Kexian Zhu.
Nature Protocols (2013)

1105 Citations

Derivation of blood-brain barrier endothelial cells from human pluripotent stem cells

Ethan S Lippmann;Samira M Azarin;Jennifer E Kay;Randy A Nessler.
Nature Biotechnology (2012)

485 Citations

Regulation of Cell Migration by the Calcium-dependent Protease Calpain

Anna Huttenlocher;Sean P. Palecek;Qin Lu;Wenli Zhang.
Journal of Biological Chemistry (1997)

462 Citations

Extracellular Matrix Promotes Highly Efficient Cardiac Differentiation of Human Pluripotent Stem Cells: The Matrix Sandwich Method

Jianhua Zhang;Matthew Klos;Gisela F. Wilson;Amanda M. Herman.
Circulation Research (2012)

450 Citations

Physical and biochemical regulation of integrin release during rear detachment of migrating cells.

Sean P. Palecek;Anna Huttenlocher;Alan F. Horwitz;Douglas A. Lauffenburger.
Journal of Cell Science (1998)

347 Citations

A retinoic acid-enhanced, multicellular human blood-brain barrier model derived from stem cell sources

Ethan S. Lippmann;Abraham Al-Ahmad;Samira M. Azarin;Sean P. Palecek.
Scientific Reports (2015)

304 Citations

3-D microwell culture of human embryonic stem cells

Jeffrey C. Mohr;Jeffrey C. Mohr;Juan J. de Pablo;Juan J. de Pablo;Sean P. Palecek;Sean P. Palecek.
Biomaterials (2006)

272 Citations

Editorial Boards

BMC Biotechnology
(Impact Factor: 3.329)

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