2014 - Fellow of the Indian National Academy of Engineering (INAE)
Sean P. Palecek spends much of his time researching Cell biology, Embryonic stem cell, Induced pluripotent stem cell, Cellular differentiation and Extracellular matrix. He specializes in Cell biology, namely Stem cell. His Embryonic stem cell study incorporates themes from Immunology, Molecular biology and Matrigel.
His Induced pluripotent stem cell research is multidisciplinary, incorporating elements of SOX2, Internal medicine, Monocarboxylate transporter and Blood–brain barrier. His Cellular differentiation study integrates concerns from other disciplines, such as Endothelial stem cell, Wnt signaling pathway, Activin type 2 receptors, NODAL and Flow cytometry. His Extracellular matrix research incorporates elements of Mechanotransduction, Cell migration and Cell type.
Sean P. Palecek mainly investigates Cell biology, Induced pluripotent stem cell, Embryonic stem cell, Stem cell and Cellular differentiation. His biological study spans a wide range of topics, including Endothelial stem cell, Cell culture and Cell. His Cell culture study combines topics in areas such as Biotechnology and Nanotechnology.
Sean P. Palecek has included themes like In vitro, Regenerative medicine, Cell type and Blood–brain barrier in his Induced pluripotent stem cell study. His Embryonic stem cell study which covers Extracellular matrix that intersects with Biophysics. His research in Cellular differentiation intersects with topics in Flow cytometry, Immunology, Keratinocyte, Directed differentiation and Cell fate determination.
His primary areas of study are Induced pluripotent stem cell, Cell biology, Blood–brain barrier, Pericyte and Cell. Sean P. Palecek has researched Induced pluripotent stem cell in several fields, including Progenitor cell, Phenotype, Computational biology and Cellular differentiation. His work in Cellular differentiation tackles topics such as Gene expression which are related to areas like Sarcomere organization.
His studies in Cell biology integrate themes in fields like In vitro, Transcriptome, Neural crest, Morphogenesis and Cell type. The concepts of his Blood–brain barrier study are interwoven with issues in Human Induced Pluripotent Stem Cells, Neurovascular bundle, Stem cell and Tight junction. His research integrates issues of Embryonic stem cell and Flow cytometry in his study of Forebrain.
His scientific interests lie mostly in Induced pluripotent stem cell, Cell biology, Blood–brain barrier, Barrier function and Human brain. His work in Induced pluripotent stem cell addresses issues such as Progenitor cell, which are connected to fields such as Neuroscience, Calcium signaling, Mesoderm, Wnt signaling pathway and Directed differentiation. His Cell biology research integrates issues from Pericyte, Ion channel, Cellular differentiation and In vivo.
He interconnects Human Induced Pluripotent Stem Cells, Neurovascular bundle, Stem cell and Astrocyte in the investigation of issues within Blood–brain barrier. His Stem cell research is multidisciplinary, incorporating perspectives in Embryonic stem cell, Forebrain and Neural crest. His Barrier function study incorporates themes from Extracellular matrix component, Endothelium, Tight junction and CD44.
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Integrin-ligand binding properties govern cell migration speed through cell-substratum adhesiveness
Sean P. Palecek;Joseph C. Loftus;Mark H. Ginsberg;Douglas A. Lauffenburger.
Functional Cardiomyocytes Derived From Human Induced Pluripotent Stem Cells
Jianhua Zhang;Gisela F. Wilson;Andrew G. Soerens;Chad H. Koonce.
Circulation Research (2009)
Robust cardiomyocyte differentiation from human pluripotent stem cells via temporal modulation of canonical Wnt signaling
Xiaojun Lian;Cheston Hsiao;Gisela Wilson;Kexian Zhu.
Proceedings of the National Academy of Sciences of the United States of America (2012)
Directed cardiomyocyte differentiation from human pluripotent stem cells by modulating Wnt/β-catenin signaling under fully defined conditions
Xiaojun Lian;Jianhua Zhang;Samira M Azarin;Kexian Zhu.
Nature Protocols (2013)
Derivation of blood-brain barrier endothelial cells from human pluripotent stem cells
Ethan S Lippmann;Samira M Azarin;Jennifer E Kay;Randy A Nessler.
Nature Biotechnology (2012)
Regulation of Cell Migration by the Calcium-dependent Protease Calpain
Anna Huttenlocher;Sean P. Palecek;Qin Lu;Wenli Zhang.
Journal of Biological Chemistry (1997)
Extracellular Matrix Promotes Highly Efficient Cardiac Differentiation of Human Pluripotent Stem Cells: The Matrix Sandwich Method
Jianhua Zhang;Matthew Klos;Gisela F. Wilson;Amanda M. Herman.
Circulation Research (2012)
Physical and biochemical regulation of integrin release during rear detachment of migrating cells.
Sean P. Palecek;Anna Huttenlocher;Alan F. Horwitz;Douglas A. Lauffenburger.
Journal of Cell Science (1998)
A retinoic acid-enhanced, multicellular human blood-brain barrier model derived from stem cell sources
Ethan S. Lippmann;Abraham Al-Ahmad;Samira M. Azarin;Sean P. Palecek.
Scientific Reports (2015)
3-D microwell culture of human embryonic stem cells
Jeffrey C. Mohr;Jeffrey C. Mohr;Juan J. de Pablo;Juan J. de Pablo;Sean P. Palecek;Sean P. Palecek.
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