What is he best known for?
The fields of study he is best known for:
Cell biology, Signal transduction, Epidermal growth factor, Cell migration and Cell adhesion are his primary areas of study.
His study in Cell biology is interdisciplinary in nature, drawing from both Receptor, Integrin, Epidermal growth factor receptor and Calpain.
His research integrates issues of Computational biology, Systems biology, Bioinformatics and Autocrine signalling in his study of Signal transduction.
The study incorporates disciplines such as Extracellular matrix, Biological system and Motility in addition to Cell migration.
His research in Cell adhesion tackles topics such as Fibronectin which are related to areas like Shear stress.
Douglas A. Lauffenburger focuses mostly in the field of Cell, narrowing it down to matters related to Immunology and, in some cases, Secretion.
His most cited work include:
- Cell Migration: A Physically Integrated Molecular Process (3428 citations)
- Causal Protein-Signaling Networks Derived from Multiparameter Single-Cell Data (1291 citations)
- Integrin-ligand binding properties govern cell migration speed through cell-substratum adhesiveness (1232 citations)
What are the main themes of his work throughout his whole career to date?
His main research concerns Cell biology, Signal transduction, Immunology, Cell and Receptor.
His Cell biology research includes elements of Epidermal growth factor, Cell migration, Autocrine signalling and Epidermal growth factor receptor.
The Cell migration study which covers Extracellular matrix that intersects with Integrin.
His Signal transduction study combines topics from a wide range of disciplines, such as Cancer research, Phosphorylation and Bioinformatics.
Antibody, Cytokine, Immune system and T cell are the primary areas of interest in his Immunology study.
His research investigates the connection between Motility and topics such as Biophysics that intersect with issues in Chemotaxis, Biochemistry and Cell adhesion.
He most often published in these fields:
- Cell biology (36.75%)
- Signal transduction (16.27%)
- Immunology (16.01%)
What were the highlights of his more recent work (between 2014-2021)?
- Immunology (16.01%)
- Cell biology (36.75%)
- Cancer research (10.10%)
In recent papers he was focusing on the following fields of study:
The scientist’s investigation covers issues in Immunology, Cell biology, Cancer research, Immune system and Antibody.
His studies in Signal transduction, Extracellular matrix, MAPK/ERK pathway, Cell signaling and Crosstalk are all subfields of Cell biology research.
His research in Signal transduction focuses on subjects like Phosphorylation, which are connected to Epidermal growth factor and Kinase.
His Cancer research study combines topics in areas such as Cancer, Metastasis, Cell and Receptor tyrosine kinase.
His Cell research includes themes of Tumor microenvironment, Phenotype, Computational biology and Matrix metalloproteinase.
He interconnects Vaccination, Virology and Immunity in the investigation of issues within Antibody.
Between 2014 and 2021, his most popular works were:
- Single-shot Ad26 vaccine protects against SARS-CoV-2 in rhesus macaques. (303 citations)
- Eradication of large established tumors in mice by combination immunotherapy that engages innate and adaptive immune responses (267 citations)
- A Functional Role for Antibodies in Tuberculosis (251 citations)
In his most recent research, the most cited papers focused on:
Douglas A. Lauffenburger mostly deals with Immunology, Antibody, Cell biology, Cancer research and Cytokine.
His work in Immunology addresses issues such as Proteases, which are connected to fields such as Menstrual cycle, Cell adhesion molecule, Hormone and Luteal phase.
The various areas that Douglas A. Lauffenburger examines in his Antibody study include Innate immune system, Immune system, Immunity and Vaccination.
His Cell biology research incorporates themes from Receptor and Downregulation and upregulation.
His Cancer research research incorporates elements of Cancer, Metastasis, Signal transduction and Phosphoproteomics.
His Signal transduction research integrates issues from Epidermal growth factor, Autocrine signalling, Systems biology, Bioinformatics and Phosphorylation.
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