H. Steven Wiley

What is he best known for?

The fields of study he is best known for:

• Gene
• Signal transduction
• Genetics

The scientist’s investigation covers issues in Cell biology, Epidermal growth factor, Receptor, Signal transduction and Epidermal growth factor receptor. His research brings together the fields of Endocytic cycle and Cell biology. His studies in Epidermal growth factor integrate themes in fields like ERBB3 and MAPK/ERK pathway.

His MAPK/ERK pathway research is multidisciplinary, relying on both Confluency, Cell signaling and Cytoplasm. Signal transduction connects with themes related to Endosome in his study. As a part of the same scientific study, H. Steven Wiley usually deals with the Epidermal growth factor receptor, concentrating on Endocytosis and frequently concerns with Cell type, Antibody, Cell physiology, Mutation and Mutant.

His most cited work include:

• The enhanced tumorigenic activity of a mutant epidermal growth factor receptor common in human cancers is mediated by threshold levels of constitutive tyrosine phosphorylation and unattenuated signaling. (531 citations)
• Flow-cytometric isolation of human antibodies from a nonimmune Saccharomyces cerevisiae surface display library (473 citations)
• Trafficking of the ErbB receptors and its influence on signaling. (328 citations)

What are the main themes of his work throughout his whole career to date?

His primary areas of investigation include Cell biology, Epidermal growth factor receptor, Receptor, Signal transduction and Epidermal growth factor. The concepts of his Cell biology study are interwoven with issues in Internalization and Autocrine signalling. His studies in Epidermal growth factor receptor integrate themes in fields like Downregulation and upregulation and Transactivation.

His Receptor study incorporates themes from Molecular biology and Cell membrane. Confluency, Cytoplasm and Selected reaction monitoring is closely connected to Phosphorylation in his research, which is encompassed under the umbrella topic of Signal transduction. His Epidermal growth factor research is multidisciplinary, relying on both Endosome and Tyrosine phosphorylation.

He most often published in these fields:

• Cell biology (67.09%)
• Epidermal growth factor receptor (43.04%)
• Receptor (36.71%)

What were the highlights of his more recent work (between 2011-2019)?

• Receptor (36.71%)
• Phosphorylation (16.46%)
• Selected reaction monitoring (3.80%)

In recent papers he was focusing on the following fields of study:

His primary areas of study are Receptor, Phosphorylation, Selected reaction monitoring, Signal transduction and Epidermal growth factor receptor. His Receptor research is multidisciplinary, incorporating perspectives in Melanoma, Kinase, Cell biology and Transduction. His work is connected to Receptor tyrosine kinase and ERBB3, as a part of Cell biology.

His Protein kinase A and MAPK/ERK pathway study in the realm of Phosphorylation interacts with subjects such as Phosphoproteomics and Context. Epidermal growth factor receptor and ErbB are frequently intertwined in his study. His Cancer research incorporates elements of Epidermal growth factor, Autocrine signalling and Cancer research.

Between 2011 and 2019, his most popular works were:

• Sensitive targeted quantification of ERK phosphorylation dynamics and stoichiometry in human cells without affinity enrichment. (27 citations)
• Targeted Quantification of Phosphorylation Dynamics in the Context of EGFR-MAPK Pathway. (24 citations)
• Coregulation of Terpenoid Pathway Genes and Prediction of Isoprene Production in Bacillus subtilis Using Transcriptomics (21 citations)

In his most recent research, the most cited papers focused on:

• Gene
• Genetics
• Signal transduction

H. Steven Wiley mostly deals with Selected reaction monitoring, Phosphorylation, Reagent, Terpenoid and Bacillus subtilis. His work carried out in the field of Selected reaction monitoring brings together such families of science as Epidermal growth factor receptor and Signal transduction, MAPK/ERK pathway, Biochemistry. His work on Protein kinase A as part of general Phosphorylation research is frequently linked to Context, bridging the gap between disciplines.

Gene isoform, Targeted mass spectrometry, Chromatography, Proteomics and Biophysics are fields of study that intersect with his Reagent study. H. Steven Wiley combines subjects such as Transcriptome, Gene expression and Gene with his study of Terpenoid. His Bacillus subtilis study spans across into subjects like Genetics and Regulation of gene expression.