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Linda G. Griffith

Linda G. Griffith

D-Index & Metrics

Biology and Biochemistry

D-Index
94
Citations
36116
World Ranking
1990
National Ranking
1085

Research.com Recognitions

  • 2018 - Fellow, National Academy of Inventors
  • 2011 - Member of the National Academy of Engineering For contributions to 3D functional biomaterials, engineered hepatic tissues, and cell transplant devices.
  • 2006 - Fellow of the MacArthur Foundation
  • 2000 - Fellow of Biomaterials Science and Engineering
  • 1999 - Fellow of the Indian National Academy of Engineering (INAE)

Overview

Linda G. Griffith is affiliated with the Massachusetts Institute of Technology (MIT) in the United States. Their research spans multiple disciplines within Medicine and Biochemistry, Genetics and Molecular Biology, with a pronounced focus on Biomedical Engineering, Molecular Biology, Immunology, Reproductive Medicine, and Obstetrics and Gynecology.

The scientist's work covers a range of topics, including:

  • Endometriosis Research and Treatment
  • 3D Printing in Biomedical Research
  • Reproductive System and Pregnancy
  • Uterine Myomas and Treatments
  • Gut microbiota and health
  • Liver physiology and pathology
  • Cancer Cells and Metastasis

Frequent publication venues for their work include:

  • bioRxiv (Cold Spring Harbor Laboratory)
  • Clinical Immunology
  • Molecular Human Reproduction
  • Biomaterials
  • Journal of Minimally Invasive Gynecology

Notable recent papers authored or coauthored by Linda G. Griffith include:

  • "Menstruation: science and society" (2020) published in American Journal of Obstetrics and Gynecology
  • "Gut-Liver Physiomimetics Reveal Paradoxical Modulation of IBD-Related Inflammation by Short-Chain Fatty Acids" (2020) published in Cell Systems
  • "A microenvironment-inspired synthetic three-dimensional model for pancreatic ductal adenocarcinoma organoids" (2021) published in Nature Materials
  • "Fully synthetic matrices for in vitro culture of primary human intestinal enteroids and endometrial organoids" (2020) published in Biomaterials
  • "Human physiomimetic model integrating microphysiological systems of the gut, liver, and brain for studies of neurodegenerative diseases" (2021) published in Science Advances

Frequent collaborators in their research include:

  • Victor Hernandez-Gordillo
  • Juan S. Gnecco
  • Alexander Brown
  • Erin Greaves
  • Kaylon L. Bruner-Tran

Throughout their career, Linda G. Griffith has received several recognitions and awards, such as:

  • Fellow of the Indian National Academy of Engineering (INAE), 1999
  • Fellow of Biomaterials Science and Engineering, 2000
  • Fellow of the MacArthur Foundation, 2006
  • Member of the National Academy of Engineering, 2011, for contributions to 3D functional biomaterials, engineered hepatic tissues, and cell transplant devices
  • Fellow, National Academy of Inventors, 2018

Best Publications

  • Tissue Engineering--Current Challenges and Expanding Opportunities

    Linda G. Griffith;Gail Naughton

  • Regulation of transport pathways in tumor vessels: Role of tumor type and microenvironment

    S. K. Hobbs;W. L. Monsky;Fan Yuan;W. G. Roberts

  • Capturing complex 3D tissue physiology in vitro.

    Linda G. Griffith;Melody A. Swartz

  • Cell adhesion and motility depend on nanoscale RGD clustering.

    G. Maheshwari;G. Brown;D.A. Lauffenburger;A. Wells

  • Engineering principles of clinical cell-based tissue engineering.

    George F. Muschler;Chizu Nakamoto;Linda G. Griffith

  • Effect of pore size and void fraction on cellular adhesion, proliferation, and matrix deposition.

    Joan Zeltinger;Jill K. Sherwood;Dionne A. Graham;Ralph Müeller

  • A three-dimensional osteochondral composite scaffold for articular cartilage repair.

    Jill K Sherwood;Susan L Riley;Robert Palazzolo;Scott C Brown

  • Emerging design principles in biomaterials and scaffolds for tissue engineering.

    Linda G. Griffith

  • A microfabricated array bioreactor for perfused 3D liver culture

    Mark J. Powers;Karel Domansky;Mohammad R. Kaazempur-Mofrad;Artemis Kalezi

  • Survival and function of hepatocytes on a novel three-dimensional synthetic biodegradable polymer scaffold with an intrinsic network of channels

    Stephen S. Kim;Hirofumi Utsunomiya;John A. Koski;Benjamin M. Wu

  • Injectable composition containing crosslinkable material and cells for forming animal tissue

    Linda G. Griffith;Anthony Atala;Charles A. Vacanti;Keith T. Paige

  • Co-regulation of cell adhesion by nanoscale RGD organization and mechanical stimulus

    Lily Y. Koo;Darrell J. Irvine;Anne M. Mayes;Douglas A. Lauffenburger

  • In vitro models for liver toxicity testing.

    Valerie Y. Soldatow;Edward L. LeCluyse;Linda G. Griffith;Ivan Rusyn

  • Microfluidic Shear Devices for Quantitative Analysis of Cell Adhesion

    Hang Lu;Lily Y. Koo;Wechung M. Wang;Douglas A. Lauffenburger

  • Perfused multiwell plate for 3D liver tissue engineering

    Karel Domansky;Walker Inman;James Serdy;Ajit Dash

  • Interconnected Microphysiological Systems for Quantitative Biology and Pharmacology Studies

    Collin D. Edington;Wen Li Kelly Chen;Emily Geishecker;Timothy Kassis

  • Integration of surface modification and 3D fabrication techniques to prepare patterned poly(L-lactide) substrates allowing regionally selective cell adhesion.

    Ann Park;Ben Wu;Linda G. Griffith

  • A microscale in vitro physiological model of the liver: predictive screens for drug metabolism and enzyme induction.

    A. Sivaraman;J. K. Leach;S. Townsend;T. Iida

  • Vascularized perfused microtissue/micro-organ arrays

    Linda G. Griffith;Steven R. Tannenbaum;Mark J. Powers;Karel Domansky

  • Current concepts review: Engineering principles of clinical cell-based tissue engineering

    George F. Muschler;Chizu Nakamoto;Linda G. Griffith

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