Leonardo Pardo

Overview

Best Publications

• Crystal structure of the µ-opioid receptor bound to a morphinan antagonist

  Aashish Manglik;Andrew C. Kruse;Tong Sun Kobilka;Foon Sun Thian

  1616
  Citations

• Ligand-specific regulation of the extracellular surface of a G-protein-coupled receptor

  Michael P. Bokoch;Yaozhong Zou;Søren G F Rasmussen;Corey W. Liu

  585
  Citations

• A molecular dissection of the glycoprotein hormone receptors.

  Gilbert Vassart;Leonardo Pardo;Sabine Costagliola

  480
  Citations

• Glycoprotein hormone receptors: determinants in leucine-rich repeats responsible for ligand specificity

  Guillaume Smits;Mercedes Campillo;Cédric Govaerts;Cédric Govaerts;Véronique Janssens

  234
  Citations

• Cognitive Impairment Induced by Delta9-tetrahydrocannabinol Occurs through Heteromers between Cannabinoid CB1 and Serotonin 5-HT2A Receptors.

  Xavier Viñals;Estefanía Moreno;Laurence Lanfumey;Arnau Cordomí

  232
  Citations

• Pharmacogenomic and Structural Analysis of Constitutive G Protein–Coupled Receptor Activity

  Martine J Smit;Henry F Vischer;Remko A Bakker;Aldo Jongejan

  230
  Citations

• Ligand-regulated oligomerization of β2-adrenoceptors in a model lipid bilayer

  Juan José Fung;Xavier Deupi;Leonardo Pardo;Xiao Jie Yao

  221
  Citations

• Serine and Threonine Residues Bend α-Helices in the χ1 = g− Conformation

  Juan A. Ballesteros;Xavier Deupi;Mireia Olivella;Eric E.J. Haaksma

  209
  Citations

• Serotonin 5-HT6 receptor antagonists for the treatment of cognitive deficiency in Alzheimer's disease.

  Bellinda Benhamú;Mar Martín-Fontecha;Henar Vázquez-Villa;Leonardo Pardo

  171
  Citations

• The TXP motif in the second transmembrane helix of CCR5. A structural determinant of chemokine-induced activation.

  Cédric Govaerts;Cédric Blanpain;Xavier Deupi;Sébastien Ballet

  171
  Citations

• Membrane Protein Simulations Using AMBER Force Field and Berger Lipid Parameters

  Arnau Cordomí;Gianluigi Caltabiano;Leonardo Pardo

  165
  Citations

• Synthesis and pharmacophore modeling of naphthoquinone derivatives with cytotoxic activity in human promyelocytic leukemia HL-60 cell line.

  Elisa Pérez-Sacau;Raquel G. Díaz-Peńate;Ana Estévez-Braun;Angel G. Ravelo

  163
  Citations

• The role of internal water molecules in the structure and function of the rhodopsin family of G protein-coupled receptors.

  Leonardo Pardo;Xavier Deupi;Nicole Dölker;María Luz López-Rodríguez

  150
  Citations

• An activation switch in the rhodopsin family of G protein-coupled receptors: the thyrotropin receptor.

  Eneko Urizar;Eneko Urizar;Sylvie Claeysen;Xavier Deupí;Cedric Govaerts

  142
  Citations

• Interactions between Intracellular Domains as Key Determinants of the Quaternary Structure and Function of Receptor Heteromers

  Gemma Navarro;Sergi Ferré;Arnau Cordomi;Estefania Moreno

  141
  Citations

• Quaternary structure of a G-protein-coupled receptor heterotetramer in complex with Gi and Gs

  Gemma Navarro;Arnau Cordomí;Monika Zelman-Femiak;Monika Zelman-Femiak;Marc Brugarolas

  129
  Citations

• A Conserved Asn in Transmembrane Helix 7 Is an On/Off Switch in the Activation of the Thyrotropin Receptor

  Cédric Govaerts;Anne Lefort;Sabine Costagliola;Shoshana Wodak

  127
  Citations

• Evidence for functional pre-coupled complexes of receptor heteromers and adenylyl cyclase.

  Gemma Navarro;Arnau Cordomí;Verónica Casadó-Anguera;Estefanía Moreno

  126
  Citations

• A Three-Dimensional Pharmacophore Model for 5-Hydroxytryptamine6 (5-HT6) Receptor Antagonists

  María L López-Rodríguez;Bellinda Benhamú;Tania de la Fuente;Arantxa Sanz

  123
  Citations

• Linking agonist binding to histamine H1 receptor activation.

  Aldo Jongejan;Martijn Bruysters;Juan A Ballesteros;Eric Haaksma

  122
  Citations

• Ligand-regulated oligomerization of b 2 -adrenoceptors in a model lipid bilayer This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits distribution,andreproductioninanymedium,providedtheoriginalauthorandsourcearecredited.Thislicensedoesnot permit commercial exploitation without specific permission.

  Xavier Deupi;Leonardo Pardo;Xiao Jie Yao;Gisselle A Velez-Ruiz

  2
  Citations