World's Best Scientists 2026 revealed!

D-Index & Metrics

Chemistry

D-Index
57
Citations
9811
World Ranking
11293
National Ranking
219

Chris de Graaf publication distribution in Chemistry in 2026

The chart shows the distribution of publications by all Research.com ranked scientists in the field of Chemistry in 2026. The highlighted bar marks where Chris de Graaf sits on this spectrum.

61–80 publications: 66 scientists 81–100 publications: 302 scientists 101–120 publications: 623 scientists 121–140 publications: 918 scientists 141–160 publications: 1,218 scientists 161–180 publications: 1,350 scientists 181–200 publications: 1,344 scientists 201–220 publications: 1,281 scientists 221–240 publications: 1,216 scientists 241–260 publications: 1,100 scientists 261–280 publications: 979 scientists 281–300 publications: 939 scientists 301–320 publications: 764 scientists 321–340 publications: 643 scientists 341–360 publications: 628 scientists 361–380 publications: 522 scientists 381–400 publications: 459 scientists 401–420 publications: 397 scientists 421–440 publications: 327 scientists 441–460 publications: 270 scientists 461–480 publications: 265 scientists 481–500 publications: 252 scientists 501–520 publications: 201 scientists 521–540 publications: 185 scientists 541–560 publications: 148 scientists 561–580 publications: 148 scientists 581–600 publications: 132 scientists 601–620 publications: 114 scientists 621–640 publications: 104 scientists 641–660 publications: 91 scientists 661–680 publications: 92 scientists 681–700 publications: 73 scientists 701–720 publications: 57 scientists 721–740 publications: 54 scientists 741–760 publications: 67 scientists 761–780 publications: 45 scientists 781–800 publications: 46 scientists 801–820 publications: 39 scientists 821–840 publications: 32 scientists 841–860 publications: 36 scientists 861–880 publications: 29 scientists 881–900 publications: 26 scientists 901–920 publications: 24 scientists 921–940 publications: 14 scientists 941–960 publications: 23 scientists 961–980 publications: 28 scientists 981–1,000 publications: 15 scientists 1,001–1,020 publications: 29 scientists 1,021–1,040 publications: 12 scientists 1,041–1,060 publications: 19 scientists 1,061–1,080 publications: 12 scientists 1,081–1,100 publications: 6 scientists 1,101–1,120 publications: 8 scientists 1,121–1,140 publications: 12 scientists 1,141–1,160 publications: 5 scientists 1,161–1,180 publications: 6 scientists 1,181–1,200 publications: 14 scientists 1,201–1,220 publications: 7 scientists 1,221–1,240 publications: 2 scientists 1,241–1,260 publications: 6 scientists 1,261–1,280 publications: 4 scientists 1,281–1,294 publications: 6 scientists 1,295+ publications: 100 scientists
61 publications 1,295+

This scientist: 135 publications — 9th percentile

9% of scientists in this discipline score the same or lower.

The last bar groups every scientist with 1,295 publications or more.

Chris de Graaf D-index placement in Chemistry in 2026

The chart shows the D-index (discipline H-index) distribution of Chemistry scientists ranked by Research.com in 2026. The highlighted bar marks where Chris de Graaf sits on this spectrum.

40–41 D-Index: 289 scientists 42–43 D-Index: 612 scientists 44–45 D-Index: 808 scientists 46–47 D-Index: 776 scientists 48–49 D-Index: 835 scientists 50–51 D-Index: 861 scientists 52–53 D-Index: 872 scientists 54–55 D-Index: 933 scientists 56–57 D-Index: 1,051 scientists 58–59 D-Index: 930 scientists 60–61 D-Index: 882 scientists 62–63 D-Index: 834 scientists 64–65 D-Index: 731 scientists 66–67 D-Index: 775 scientists 68–69 D-Index: 683 scientists 70–71 D-Index: 646 scientists 72–73 D-Index: 561 scientists 74–75 D-Index: 501 scientists 76–77 D-Index: 437 scientists 78–79 D-Index: 388 scientists 80–81 D-Index: 354 scientists 82–83 D-Index: 292 scientists 84–85 D-Index: 275 scientists 86–87 D-Index: 254 scientists 88–89 D-Index: 235 scientists 90–91 D-Index: 185 scientists 92–93 D-Index: 192 scientists 94–95 D-Index: 155 scientists 96–97 D-Index: 163 scientists 98–99 D-Index: 125 scientists 100–101 D-Index: 105 scientists 102–103 D-Index: 105 scientists 104–105 D-Index: 112 scientists 106–107 D-Index: 88 scientists 108–109 D-Index: 68 scientists 110–111 D-Index: 69 scientists 112–113 D-Index: 65 scientists 114–115 D-Index: 79 scientists 116–117 D-Index: 61 scientists 118–119 D-Index: 44 scientists 120–121 D-Index: 37 scientists 122–123 D-Index: 40 scientists 124–125 D-Index: 33 scientists 126–127 D-Index: 26 scientists 128–129 D-Index: 34 scientists 130–131 D-Index: 35 scientists 132–133 D-Index: 25 scientists 134–135 D-Index: 27 scientists 136–137 D-Index: 17 scientists 138–139 D-Index: 16 scientists 140–141 D-Index: 20 scientists 142–143 D-Index: 20 scientists 144–145 D-Index: 15 scientists 146–147 D-Index: 9 scientists 148–149 D-Index: 9 scientists 150–151 D-Index: 16 scientists 152–153 D-Index: 11 scientists 154–155 D-Index: 9 scientists 156–157 D-Index: 3 scientists 158 D-Index: 3 scientists 159+ D-Index: 98 scientists
40 D-Index 159+

This scientist: 57 D-Index — 39th percentile

39% of scientists in this discipline score the same or lower.

The last bar groups every scientist with 159 D-Index or more.

Overview

Chris de Graaf is affiliated with Vrije Universiteit Amsterdam in the Netherlands. Their research focus falls within the broad field of Biochemistry, Genetics and Molecular Biology, with a particular emphasis on Molecular Biology, Cellular and Molecular Neuroscience, and Computational Theory and Mathematics among other subfields.

The scientist's recent publications illustrate a strong involvement in receptor biology and drug discovery. Notable papers include:

  • Impact of GPCR Structures on Drug Discovery, 2020, Cell
  • Advances in therapeutic peptides targeting G protein-coupled receptors, 2020, Nature Reviews Drug Discovery
  • KLIFS: an overhaul after the first 5 years of supporting kinase research, 2020, Nucleic Acids Research
  • Structure-Based Virtual Screening for Ligands of G Protein-Coupled Receptors: What Can Molecular Docking Do for You?, 2021, Pharmacological Reviews
  • From structure to clinic: Design of a muscarinic M1 receptor agonist with the potential to treat Alzheimer's disease, 2021, Cell

Their research encompasses topics such as Receptor Mechanisms and Signaling, Computational Drug Discovery Methods, and Neuropeptides and Animal Physiology. Additional topics include Machine Learning in Materials Science, Chemical Synthesis and Analysis, Chemokine receptors and signaling, and Monoclonal and Polyclonal Antibodies Research.

Chris de Graaf frequently publishes in journals such as:

  • Journal of Cheminformatics
  • Journal of Chemical Information and Modeling
  • bioRxiv (Cold Spring Harbor Laboratory)
  • Cell
  • Proceedings of the National Academy of Sciences

The scientist often collaborates with several colleagues, including Rob Leurs, Iwan J. P. de Esch, Andreas Bender, Noel M. O'Boyle, and Francesca Deflorian.

Best Publications

  • Generic GPCR residue numbers – aligning topology maps while minding the gaps

    Vignir Isberg;Chris de Graaf;Andrea Bortolato;Vadim Cherezov

  • Structure of the human glucagon class B G-protein-coupled receptor

    Fai Yiu Siu;Min He;Chris De Graaf;Gye Won Han

  • Glucagon-like peptide-1 and its class B G protein-coupled receptors: A long march to therapeutic successes

    Chris de Graaf;Dan Donnelly;Denise Wootten;Jesper Lau

  • Impact of GPCR Structures on Drug Discovery

    Miles Congreve;Chris de Graaf;Nigel A. Swain;Christopher G. Tate

  • KLIFS: a knowledge-based structural database to navigate kinase-ligand interaction space.

    Oscar P J van Linden;Albert J Kooistra;Rob Leurs;Iwan J P de Esch

  • Ligand efficiency as a guide in fragment hit selection and optimization

    Sabine Schultes;Chris de Graaf;Eric E.J. Haaksma;Eric E.J. Haaksma;Iwan J.P. de Esch

  • Cytochrome P450 in Silico: An Integrative Modeling Approach

    de Graaf, , C.;N.P.E. Vermeulen;K.A. Feenstra

  • Advances in therapeutic peptides targeting G protein-coupled receptors

    Anthony P. Davenport;Conor C. G. Scully;Chris de Graaf;Alastair J. H. Brown

  • Insights into the structure of class B GPCRs.

    Kaspar Hollenstein;Chris de Graaf;Andrea Bortolato;Ming-Wei Wang

  • Crystal structure-based virtual screening for novel fragment-like ligands of the human histamine H1 receptor

    Chris de Graaf;Albert J. Kooistra;Henry F. Vischer;Vsevolod Katritch

  • Human GLP-1 receptor transmembrane domain structure in complex with allosteric modulators

    Gaojie Song;Dehua Yang;Yuxia Wang;Chris de Graaf

  • Diazepam-bound GABAA receptor models identify new benzodiazepine binding-site ligands

    Lars Richter;Chris de Graaf;Werner Sieghart;Zdravko Varagic

  • Kinetics for Drug Discovery: an industry-driven effort to target drug residence time.

    Doris A. Schuetz;Wilhelmus Egbertus Arnout de Witte;Yin Cheong Wong;Bernhard Knasmueller

  • Structure of the full-length glucagon class B G-protein-coupled receptor

    Haonan Zhang;Anna Qiao;Dehua Yang;Linlin Yang

  • Structure-Based Virtual Screening for Ligands of G Protein–Coupled Receptors: What Can Molecular Docking Do for You?

    Unknown

  • KLIFS: a structural kinase-ligand interaction database

    Albert J. Kooistra;Georgi K. Kanev;Oscar P.J. van Linden;Rob Leurs

  • Binding mode prediction of cytochrome p450 and thymidine kinase protein-ligand complexes by consideration of water and rescoring in automated docking.

    Chris de Graaf;Pavel Pospisil;Wouter Pos;Gerd Folkers

  • Catalytic site prediction and virtual screening of cytochrome P450 2D6 substrates by consideration of water and rescoring in automated docking.

    Chris de Graaf;Chris Oostenbrink;Peter H. J. Keizers;Tushar van der Wijst

  • Selective structure-based virtual screening for full and partial agonists of the beta2 adrenergic receptor.

    Chris de Graaf;Didier Rognan

  • Extending the Structural View of Class B GPCRs

    Chris de Graaf;Gaojie Song;Can Cao;Qiang Zhao

  • Structural Analysis of Chemokine Receptor–Ligand Interactions

    Marta Arimont;Shan-Liang Sun;Rob Leurs;Martine Smit

Frequent Co-Authors

Iwan J. P. de Esch
Iwan J. P. de Esch Vrije Universiteit Amsterdam
Rob Leurs
Rob Leurs Vrije Universiteit Amsterdam
Raymond C. Stevens
Raymond C. Stevens University of Southern California
Nico P. E. Vermeulen
Nico P. E. Vermeulen Vrije Universiteit Amsterdam
Ming-Wei Wang
Ming-Wei Wang Chinese Academy of Sciences
Martine J. Smit
Martine J. Smit Vrije Universiteit Amsterdam
Didier Rognan
Didier Rognan University of Strasbourg
Jan N. M. Commandeur
Jan N. M. Commandeur Vrije Universiteit Amsterdam
Andreas Bender
Andreas Bender University of Cambridge
Miles Congreve
Miles Congreve University of Hertfordshire

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