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Chris de Graaf

D-Index & Metrics

Discipline name D-Index World Ranking Current World Ranking National Ranking Current National Ranking Publications Citations
Chemistry 57 11293 10178 219 187 135 9811

Chris de Graaf publications per year

The chart shows the history of publications by Chris de Graaf between 2004 and 2026, highlighting the no. of papers published in each year and offering an overview of the publication velocity of this scholar. Chris de Graaf published across 23 years, from 2004 to 2026, averaging 8 papers a year. Output peaked at 23 publications in 2016. 19 of the 184 publications appeared in the last two years.

No. of publications
5 10 15 20
Bar chart. Horizontal axis: year, 2004 to 2026. Vertical axis: number of publications, 0 to 23. Peak 23 publications in 2016. 2004: 2 publications 2005: 8 publications 2006: 4 publications 2007: 4 publications 2008: 2 publications 2009: 3 publications 2010: 4 publications 2011: 12 publications 2012: 9 publications 2013: 7 publications 2014: 7 publications 2015: 8 publications 2016: 23 publications 2017: 8 publications 2018: 10 publications 2019: 11 publications 2020: 8 publications 2021: 8 publications 2022: 8 publications 2023: 9 publications 2024: 10 publications 2025: 5 publications 2026: 14 publications
2004 2026

184 publications in total across all disciplines

View publications per year as a table
Chris de Graaf: publications per year, 2004 to 2026
Year Publications
2004 2
2005 8
2006 4
2007 4
2008 2
2009 3
2010 4
2011 12
2012 9
2013 7
2014 7
2015 8
2016 23
2017 8
2018 10
2019 11
2020 8
2021 8
2022 8
2023 9
2024 10
2025 5
2026 14
Total 184
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Chris de Graaf publication distribution in Chemistry in 2026

The chart shows the distribution of publications by all Research.com ranked scientists in the field of Chemistry in 2026. The highlighted bar marks where Chris de Graaf sits on this spectrum.

No. of scientists
250 500 750 1,000 1,250
Bar chart with 63 bars. Horizontal axis: publications, 61–80 to 1,295+. Vertical axis: number of scientists, 0 to 1,350. Most scientists, 1,350, have 161–180 publications. The last bar groups every scientist with 1,295 publications or more. The highlighted bar, 121–140 publications, is where this scientist sits. 61–80 publications: 66 scientists 81–100 publications: 302 scientists 101–120 publications: 623 scientists 121–140 publications: 918 scientists 141–160 publications: 1,218 scientists 161–180 publications: 1,350 scientists 181–200 publications: 1,344 scientists 201–220 publications: 1,281 scientists 221–240 publications: 1,216 scientists 241–260 publications: 1,100 scientists 261–280 publications: 979 scientists 281–300 publications: 939 scientists 301–320 publications: 764 scientists 321–340 publications: 643 scientists 341–360 publications: 628 scientists 361–380 publications: 522 scientists 381–400 publications: 459 scientists 401–420 publications: 397 scientists 421–440 publications: 327 scientists 441–460 publications: 270 scientists 461–480 publications: 265 scientists 481–500 publications: 252 scientists 501–520 publications: 201 scientists 521–540 publications: 185 scientists 541–560 publications: 148 scientists 561–580 publications: 148 scientists 581–600 publications: 132 scientists 601–620 publications: 114 scientists 621–640 publications: 104 scientists 641–660 publications: 91 scientists 661–680 publications: 92 scientists 681–700 publications: 73 scientists 701–720 publications: 57 scientists 721–740 publications: 54 scientists 741–760 publications: 67 scientists 761–780 publications: 45 scientists 781–800 publications: 46 scientists 801–820 publications: 39 scientists 821–840 publications: 32 scientists 841–860 publications: 36 scientists 861–880 publications: 29 scientists 881–900 publications: 26 scientists 901–920 publications: 24 scientists 921–940 publications: 14 scientists 941–960 publications: 23 scientists 961–980 publications: 28 scientists 981–1,000 publications: 15 scientists 1,001–1,020 publications: 29 scientists 1,021–1,040 publications: 12 scientists 1,041–1,060 publications: 19 scientists 1,061–1,080 publications: 12 scientists 1,081–1,100 publications: 6 scientists 1,101–1,120 publications: 8 scientists 1,121–1,140 publications: 12 scientists 1,141–1,160 publications: 5 scientists 1,161–1,180 publications: 6 scientists 1,181–1,200 publications: 14 scientists 1,201–1,220 publications: 7 scientists 1,221–1,240 publications: 2 scientists 1,241–1,260 publications: 6 scientists 1,261–1,280 publications: 4 scientists 1,281–1,294 publications: 6 scientists 1,295+ publications: 100 scientists
61–80 publications 1,295+

This scientist: 135 publications — 9th percentile

9% of scientists in this discipline score the same or lower.

The last bar groups every scientist with 1,295 publications or more.

View publications distribution as a table
Number of Chemistry scientists by publication count, Research.com 2026 ranking edition. Based on 17,934 ranked scientists.
Publications Scientists This scientist
61–80 66
81–100 302
101–120 623
121–140 918 135
141–160 1,218
161–180 1,350
181–200 1,344
201–220 1,281
221–240 1,216
241–260 1,100
261–280 979
281–300 939
301–320 764
321–340 643
341–360 628
361–380 522
381–400 459
401–420 397
421–440 327
441–460 270
461–480 265
481–500 252
501–520 201
521–540 185
541–560 148
561–580 148
581–600 132
601–620 114
621–640 104
641–660 91
661–680 92
681–700 73
701–720 57
721–740 54
741–760 67
761–780 45
781–800 46
801–820 39
821–840 32
841–860 36
861–880 29
881–900 26
901–920 24
921–940 14
941–960 23
961–980 28
981–1,000 15
1,001–1,020 29
1,021–1,040 12
1,041–1,060 19
1,061–1,080 12
1,081–1,100 6
1,101–1,120 8
1,121–1,140 12
1,141–1,160 5
1,161–1,180 6
1,181–1,200 14
1,201–1,220 7
1,221–1,240 2
1,241–1,260 6
1,261–1,280 4
1,281–1,294 6
1,295+ 100
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Chris de Graaf D-index placement in Chemistry in 2026

The chart shows the D-index (discipline H-index) distribution of Chemistry scientists ranked by Research.com in 2026. The highlighted bar marks where Chris de Graaf sits on this spectrum.

No. of scientists
250 500 750 1,000
Bar chart with 61 bars. Horizontal axis: D-Index, 40–41 to 159+. Vertical axis: number of scientists, 0 to 1,051. Most scientists, 1,051, have 56–57 D-Index. The last bar groups every scientist with 159 D-Index or more. The highlighted bar, 56–57 D-Index, is where this scientist sits. 40–41 D-Index: 289 scientists 42–43 D-Index: 612 scientists 44–45 D-Index: 808 scientists 46–47 D-Index: 776 scientists 48–49 D-Index: 835 scientists 50–51 D-Index: 861 scientists 52–53 D-Index: 872 scientists 54–55 D-Index: 933 scientists 56–57 D-Index: 1,051 scientists 58–59 D-Index: 930 scientists 60–61 D-Index: 882 scientists 62–63 D-Index: 834 scientists 64–65 D-Index: 731 scientists 66–67 D-Index: 775 scientists 68–69 D-Index: 683 scientists 70–71 D-Index: 646 scientists 72–73 D-Index: 561 scientists 74–75 D-Index: 501 scientists 76–77 D-Index: 437 scientists 78–79 D-Index: 388 scientists 80–81 D-Index: 354 scientists 82–83 D-Index: 292 scientists 84–85 D-Index: 275 scientists 86–87 D-Index: 254 scientists 88–89 D-Index: 235 scientists 90–91 D-Index: 185 scientists 92–93 D-Index: 192 scientists 94–95 D-Index: 155 scientists 96–97 D-Index: 163 scientists 98–99 D-Index: 125 scientists 100–101 D-Index: 105 scientists 102–103 D-Index: 105 scientists 104–105 D-Index: 112 scientists 106–107 D-Index: 88 scientists 108–109 D-Index: 68 scientists 110–111 D-Index: 69 scientists 112–113 D-Index: 65 scientists 114–115 D-Index: 79 scientists 116–117 D-Index: 61 scientists 118–119 D-Index: 44 scientists 120–121 D-Index: 37 scientists 122–123 D-Index: 40 scientists 124–125 D-Index: 33 scientists 126–127 D-Index: 26 scientists 128–129 D-Index: 34 scientists 130–131 D-Index: 35 scientists 132–133 D-Index: 25 scientists 134–135 D-Index: 27 scientists 136–137 D-Index: 17 scientists 138–139 D-Index: 16 scientists 140–141 D-Index: 20 scientists 142–143 D-Index: 20 scientists 144–145 D-Index: 15 scientists 146–147 D-Index: 9 scientists 148–149 D-Index: 9 scientists 150–151 D-Index: 16 scientists 152–153 D-Index: 11 scientists 154–155 D-Index: 9 scientists 156–157 D-Index: 3 scientists 158 D-Index: 3 scientists 159+ D-Index: 98 scientists
40–41 D-Index 159+

This scientist: 57 D-Index — 39th percentile

39% of scientists in this discipline score the same or lower.

The last bar groups every scientist with 159 D-Index or more.

View D-Index distribution as a table
Number of Chemistry scientists by D-index, Research.com 2026 ranking edition. Based on 17,934 ranked scientists.
D-Index Scientists This scientist
40–41 289
42–43 612
44–45 808
46–47 776
48–49 835
50–51 861
52–53 872
54–55 933
56–57 1,051 57
58–59 930
60–61 882
62–63 834
64–65 731
66–67 775
68–69 683
70–71 646
72–73 561
74–75 501
76–77 437
78–79 388
80–81 354
82–83 292
84–85 275
86–87 254
88–89 235
90–91 185
92–93 192
94–95 155
96–97 163
98–99 125
100–101 105
102–103 105
104–105 112
106–107 88
108–109 68
110–111 69
112–113 65
114–115 79
116–117 61
118–119 44
120–121 37
122–123 40
124–125 33
126–127 26
128–129 34
130–131 35
132–133 25
134–135 27
136–137 17
138–139 16
140–141 20
142–143 20
144–145 15
146–147 9
148–149 9
150–151 16
152–153 11
154–155 9
156–157 3
158 3
159+ 98
Download as CSV

Overview

Chris de Graaf is affiliated with Vrije Universiteit Amsterdam in the Netherlands. Their research focus falls within the broad field of Biochemistry, Genetics and Molecular Biology, with a particular emphasis on Molecular Biology, Cellular and Molecular Neuroscience, and Computational Theory and Mathematics among other subfields.

The scientist's recent publications illustrate a strong involvement in receptor biology and drug discovery. Notable papers include:

  • Impact of GPCR Structures on Drug Discovery, 2020, Cell
  • Advances in therapeutic peptides targeting G protein-coupled receptors, 2020, Nature Reviews Drug Discovery
  • KLIFS: an overhaul after the first 5 years of supporting kinase research, 2020, Nucleic Acids Research
  • Structure-Based Virtual Screening for Ligands of G Protein-Coupled Receptors: What Can Molecular Docking Do for You?, 2021, Pharmacological Reviews
  • From structure to clinic: Design of a muscarinic M1 receptor agonist with the potential to treat Alzheimer's disease, 2021, Cell

Their research encompasses topics such as Receptor Mechanisms and Signaling, Computational Drug Discovery Methods, and Neuropeptides and Animal Physiology. Additional topics include Machine Learning in Materials Science, Chemical Synthesis and Analysis, Chemokine receptors and signaling, and Monoclonal and Polyclonal Antibodies Research.

Chris de Graaf frequently publishes in journals such as:

  • Journal of Cheminformatics
  • Journal of Chemical Information and Modeling
  • bioRxiv (Cold Spring Harbor Laboratory)
  • Cell
  • Proceedings of the National Academy of Sciences

The scientist often collaborates with several colleagues, including Rob Leurs, Iwan J. P. de Esch, Andreas Bender, Noel M. O'Boyle, and Francesca Deflorian.

Best Publications

  • Generic GPCR residue numbers – aligning topology maps while minding the gaps

    Vignir Isberg;Chris de Graaf;Andrea Bortolato;Vadim Cherezov

  • Structure of the human glucagon class B G-protein-coupled receptor

    Fai Yiu Siu;Min He;Chris De Graaf;Gye Won Han

  • Glucagon-like peptide-1 and its class B G protein-coupled receptors: A long march to therapeutic successes

    Chris de Graaf;Dan Donnelly;Denise Wootten;Jesper Lau

  • Impact of GPCR Structures on Drug Discovery

    Miles Congreve;Chris de Graaf;Nigel A. Swain;Christopher G. Tate

  • KLIFS: a knowledge-based structural database to navigate kinase-ligand interaction space.

    Oscar P J van Linden;Albert J Kooistra;Rob Leurs;Iwan J P de Esch

  • Ligand efficiency as a guide in fragment hit selection and optimization

    Sabine Schultes;Chris de Graaf;Eric E.J. Haaksma;Eric E.J. Haaksma;Iwan J.P. de Esch

  • Cytochrome P450 in Silico: An Integrative Modeling Approach

    de Graaf, , C.;N.P.E. Vermeulen;K.A. Feenstra

  • Advances in therapeutic peptides targeting G protein-coupled receptors

    Anthony P. Davenport;Conor C. G. Scully;Chris de Graaf;Alastair J. H. Brown

  • Insights into the structure of class B GPCRs.

    Kaspar Hollenstein;Chris de Graaf;Andrea Bortolato;Ming-Wei Wang

  • Crystal structure-based virtual screening for novel fragment-like ligands of the human histamine H1 receptor

    Chris de Graaf;Albert J. Kooistra;Henry F. Vischer;Vsevolod Katritch

  • Human GLP-1 receptor transmembrane domain structure in complex with allosteric modulators

    Gaojie Song;Dehua Yang;Yuxia Wang;Chris de Graaf

  • Diazepam-bound GABAA receptor models identify new benzodiazepine binding-site ligands

    Lars Richter;Chris de Graaf;Werner Sieghart;Zdravko Varagic

  • Kinetics for Drug Discovery: an industry-driven effort to target drug residence time.

    Doris A. Schuetz;Wilhelmus Egbertus Arnout de Witte;Yin Cheong Wong;Bernhard Knasmueller

  • Structure of the full-length glucagon class B G-protein-coupled receptor

    Haonan Zhang;Anna Qiao;Dehua Yang;Linlin Yang

  • Structure-Based Virtual Screening for Ligands of G Protein–Coupled Receptors: What Can Molecular Docking Do for You?

    Unknown

  • KLIFS: a structural kinase-ligand interaction database

    Albert J. Kooistra;Georgi K. Kanev;Oscar P.J. van Linden;Rob Leurs

  • Binding mode prediction of cytochrome p450 and thymidine kinase protein-ligand complexes by consideration of water and rescoring in automated docking.

    Chris de Graaf;Pavel Pospisil;Wouter Pos;Gerd Folkers

  • Catalytic site prediction and virtual screening of cytochrome P450 2D6 substrates by consideration of water and rescoring in automated docking.

    Chris de Graaf;Chris Oostenbrink;Peter H. J. Keizers;Tushar van der Wijst

  • Selective structure-based virtual screening for full and partial agonists of the beta2 adrenergic receptor.

    Chris de Graaf;Didier Rognan

  • Extending the Structural View of Class B GPCRs

    Chris de Graaf;Gaojie Song;Can Cao;Qiang Zhao

  • Structural Analysis of Chemokine Receptor–Ligand Interactions

    Marta Arimont;Shan-Liang Sun;Rob Leurs;Martine Smit

Frequent Co-Authors

Iwan J. P. de Esch
Iwan J. P. de Esch Vrije Universiteit Amsterdam
Rob Leurs
Rob Leurs Vrije Universiteit Amsterdam
Raymond C. Stevens
Raymond C. Stevens University of Southern California
Nico P. E. Vermeulen
Nico P. E. Vermeulen Vrije Universiteit Amsterdam
Ming-Wei Wang
Ming-Wei Wang Chinese Academy of Sciences
Martine J. Smit
Martine J. Smit Vrije Universiteit Amsterdam
Didier Rognan
Didier Rognan University of Strasbourg
Jan N. M. Commandeur
Jan N. M. Commandeur Vrije Universiteit Amsterdam
Andreas Bender
Andreas Bender University of Cambridge
Miles Congreve
Miles Congreve University of Hertfordshire

External Links

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Finally, those considering advanced healthcare roles may wonder is it hard to become a pharmacist. While the path is demanding, a solid chemistry background is essential for success in this professional field.

Best Scientists Citing Chris de Graaf

Ming-Wei Wang

Ming-Wei Wang

Chinese Academy of Sciences

Publications: 59

Patrick M. Sexton

Patrick M. Sexton

Monash University

Publications: 58

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Denise Wootten

Monash University

Publications: 44

Stephen J. Hill

Stephen J. Hill

University of Nottingham

Publications: 40

Raymond C. Stevens

Raymond C. Stevens

University of Southern California

Publications: 40

Vsevolod Katritch

Vsevolod Katritch

University of Southern California

Publications: 38

Rebecca C. Wade

Rebecca C. Wade

Heidelberg Institute for Theoretical Studies

Publications: 37

Arthur Christopoulos

Arthur Christopoulos

Monash University

Publications: 34

H. Eric Xu

H. Eric Xu

Chinese Academy of Sciences

Publications: 34

Vadim Cherezov

Vadim Cherezov

University of Southern California

Publications: 32

Brian K. Shoichet

Brian K. Shoichet

University of California, San Francisco

Publications: 30

Bryan L. Roth

Bryan L. Roth

University of North Carolina at Chapel Hill

Publications: 27

Laurence J. Miller

Laurence J. Miller

Mayo Clinic

Publications: 23

Ruben Abagyan

Ruben Abagyan

University of California, San Diego

Publications: 23

Debbie L. Hay

Debbie L. Hay

University of Otago

Publications: 22

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Mette M. Rosenkilde

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