What is he best known for?
The fields of study he is best known for:
The scientist’s investigation covers issues in Biochemistry, Glutathione, Stereochemistry, Cytochrome P450 and Pharmacology.
Biochemistry is represented through his Microsome, Enzyme, Lipid peroxidation, Metabolism and Xenobiotic research.
His research in Glutathione intersects with topics in Carcinogen, Biotransformation, Toxicity and Dithiothreitol.
His research integrates issues of Prodrug, Drug metabolism and Genetics in his study of Cytochrome P450.
His study looks at the relationship between Pharmacology and topics such as Antioxidant, which overlap with Cytotoxicity and Biological activity.
His research investigates the link between Pollution and topics such as Sentinel species that cross with problems in Pollutant.
His most cited work include:
- Fish bioaccumulation and biomarkers in environmental risk assessment: a review (3431 citations)
- Comprehensive medicinal chemistry (1536 citations)
- Biomarkers of free radical damage: Applications in experimental animals and in humans (761 citations)
What are the main themes of his work throughout his whole career to date?
Nico P. E. Vermeulen mainly investigates Biochemistry, Cytochrome P450, Stereochemistry, Glutathione and Pharmacology.
In his research, Cytotoxicity is intimately related to Toxicity, which falls under the overarching field of Biochemistry.
His research investigates the connection between Cytochrome P450 and topics such as Mutant that intersect with issues in Regioselectivity.
The Stereochemistry study which covers Active site that intersects with Binding site.
His Glutathione research includes elements of Lipid peroxidation and Reactive intermediate.
His work on Acetaminophen as part of general Pharmacology research is frequently linked to Cisplatin, bridging the gap between disciplines.
He most often published in these fields:
- Biochemistry (45.64%)
- Cytochrome P450 (23.33%)
- Stereochemistry (22.56%)
What were the highlights of his more recent work (between 2014-2021)?
- Biochemistry (45.64%)
- Cytochrome P450 (23.33%)
- Pharmacology (16.92%)
In recent papers he was focusing on the following fields of study:
Nico P. E. Vermeulen mainly focuses on Biochemistry, Cytochrome P450, Pharmacology, Enzyme and Endocrine system.
His study involves Glutathione, NAD+ kinase, Acetaminophen, Drug metabolism and Glutathione S-transferase, a branch of Biochemistry.
His Cytochrome P450 research incorporates themes from Molecular biology, Bioassay, Mutant and Acetonitrile.
He interconnects Monooxygenase, Biosynthesis, Hydroxylation, Cofactor and Biotransformation in the investigation of issues within Mutant.
His Pharmacology research includes themes of Microsome, UGT2B7, Glucuronidation, Metabolite and Metabolism.
His Enzyme study incorporates themes from Diclofenac and Liver injury.
Between 2014 and 2021, his most popular works were:
- Legacy data sharing to improve drug safety assessment: the eTOX project. (28 citations)
- Evidence-based selection of training compounds for use in the mechanism-based integrated prediction of drug-induced liver injury in man. (28 citations)
- Inter-donor variability of phase I/phase II metabolism of three reference drugs in cryopreserved primary human hepatocytes in suspension and monolayer. (24 citations)
In his most recent research, the most cited papers focused on:
His primary scientific interests are in Pharmacology, Cytochrome P450, Enzyme, Metabolism and Interaction energy.
The Pharmacology study combines topics in areas such as Glutathione, Hormonal activity and CYP2C8.
His Cytochrome P450 research is multidisciplinary, relying on both Glucuronosyltransferase, Mutant, Toxicity and Stereochemistry.
His Stereochemistry research focuses on subjects like Benzoquinone, which are linked to Cytochrome.
The concepts of his Enzyme study are interwoven with issues in Diclofenac and Liver injury.
Biosynthesis is the subject of his research, which falls under Biochemistry.
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