Paola Chiarugi

Overview

Best Publications

• Anoikis molecular pathways and its role in cancer progression

  Paolo Paoli;Elisa Giannoni;Paola Chiarugi

  1139
  Citations

• Anoikis: an emerging hallmark in health and diseases

  ML Taddei;E Giannoni;T Fiaschi;P Chiarugi

  672
  Citations

• Reciprocal Activation of Prostate Cancer Cells and Cancer-Associated Fibroblasts Stimulates Epithelial-Mesenchymal Transition and Cancer Stemness

  Elisa Giannoni;Francesca Bianchini;Lorenzo Masieri;Sergio Serni

  655
  Citations

• Anoikis: a necessary death program for anchorage-dependent cells.

  Paola Chiarugi;Elisa Giannoni

  652
  Citations

• Cancer-associated-fibroblasts and tumour cells: a diabolic liaison driving cancer progression

  Paolo Cirri;Paola Chiarugi

  648
  Citations

• Intracellular Reactive Oxygen Species Activate Src Tyrosine Kinase during Cell Adhesion and Anchorage-Dependent Cell Growth

  Elisa Giannoni;Francesca Buricchi;Giovanni Raugei;Giampietro Ramponi

  603
  Citations

• Cancer-associated fibroblasts and M2-polarized macrophages synergize during prostate carcinoma progression.

  G Comito;E Giannoni;C P Segura;P Barcellos-de-Souza

  551
  Citations

• Reactive oxygen species as essential mediators of cell adhesion: the oxidative inhibition of a FAK tyrosine phosphatase is required for cell adhesion.

  Paola Chiarugi;Giovambattista Pani;Elisa Giannoni;Letizia Taddei

  506
  Citations

• Reciprocal Metabolic Reprogramming through Lactate Shuttle Coordinately Influences Tumor-Stroma Interplay

  Tania Fiaschi;Alberto Marini;Elisa Giannoni;Maria Letizia Taddei

  463
  Citations

• Redox regulation of protein tyrosine phosphatases during receptor tyrosine kinase signal transduction

  Paola Chiarugi;Paolo Cirri

  451
  Citations

• Oxidative stress, tumor microenvironment, and metabolic reprogramming: a diabolic liaison

  Tania Fiaschi;Paola Chiarugi

  375
  Citations

• HNE interacts directly with JNK isoforms in human hepatic stellate cells.

  M Parola;G Robino;F Marra;M Pinzani

  359
  Citations

• Lactate: A Metabolic Driver in the Tumour Landscape.

  Luigi Ippolito;Andrea Morandi;Elisa Giannoni;Paola Chiarugi

  349
  Citations

• Microenvironment and tumor cell plasticity: An easy way out.

  Maria Letizia Taddei;Elisa Giannoni;Giuseppina Comito;Paola Chiarugi

  307
  Citations

• Two vicinal cysteines confer a peculiar redox regulation to low molecular weight protein tyrosine phosphatase in response to platelet-derived growth factor receptor stimulation.

  Paola Chiarugi;Tania Fiaschi;Maria Letizia Taddei;Doriana Talini

  275
  Citations

• EMT and oxidative stress: a bidirectional interplay affecting tumor malignancy.

  Elisa Giannoni;Matteo Parri;Paola Chiarugi

  254
  Citations

• Dual Role of Mitochondrial Reactive Oxygen Species in Hypoxia Signaling: Activation of Nuclear Factor-κB via c-SRC– and Oxidant-Dependent Cell Death

  Josep M. Lluis;Francesca Buricchi;Paola Chiarugi;Albert Morales

  246
  Citations

• Protein Tyrosine Phosphorylation and Reversible Oxidation: Two Cross-Talking Posttranslation Modifications

  Paola Chiarugi;Francesca Buricchi

  239
  Citations

• Cancer associated fibroblasts exploit reactive oxygen species through a proinflammatory signature leading to epithelial mesenchymal transition and stemness.

  Elisa Giannoni;Francesca Bianchini;Lido Calorini;Paola Chiarugi

  225
  Citations

• Increased Lactate Secretion by Cancer Cells Sustains Non-cell-autonomous Adaptive Resistance to MET and EGFR Targeted Therapies.

  Maria Apicella;Elisa Giannoni;Stephany Fiore;Karin Johanna Ferrari

  224
  Citations