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Silvia Giordano

Silvia Giordano

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Biology and Biochemistry
Italy
2023

D-Index & Metrics

Biology and Biochemistry

D-Index
82
Citations
25272
World Ranking
3672
National Ranking
73

Research.com Recognitions

  • 2023 - Research.com Biology and Biochemistry in Italy Leader Award

Overview

Silvia Giordano is affiliated with the University of Turin in Italy and has made contributions to the fields of Medicine and Biochemistry, Genetics, and Molecular Biology. Their research work spans a considerable volume within oncology and molecular biology, with a strong focus on cancer research and related topics.

Research topics explored by Silvia Giordano include:

  • Gastric Cancer Management and Outcomes
  • Cancer Genomics and Diagnostics
  • Liver physiology and pathology
  • Colorectal Cancer Treatments and Studies
  • HER2/EGFR in Cancer Research
  • Genetic factors in colorectal cancer
  • Cancer Cells and Metastasis

Their publications highlight a focus on cancer types such as gastric, liver, and colorectal cancers, as well as the molecular and genetic mechanisms involved in these diseases.

Some recent papers authored or co-authored by Silvia Giordano include:

  • "Microsatellite instability in Gastric Cancer: Between lights and shadows" (2021), published in Cancer Treatment Reviews
  • "FGFR2 fusion proteins drive oncogenic transformation of mouse liver organoids towards cholangiocarcinoma" (2021), published in Journal of Hepatology
  • "The importance of being CAFs (in cancer resistance to targeted therapies)" (2022), published in Journal of Experimental & Clinical Cancer Research
  • "Thyroid hormone inhibits hepatocellular carcinoma progression via induction of differentiation and metabolic reprogramming" (2020), published in Journal of Hepatology
  • "Electrostatic Intraperitoneal Aerosol Delivery of Nanoparticles: Proof of Concept and Preclinical Validation" (2020), published in Advanced Healthcare Materials

Frequent co-authors in their research include:

  • Simona Corso
  • Simone Ribero
  • Pietro Quaglino
  • Sara E. Bellomo
  • Filippo Pietrantonio

Silvia Giordano has been published extensively in several venues, with the most frequent outlets listed as:

  • Cancers
  • Journal of Experimental & Clinical Cancer Research
  • bioRxiv (Cold Spring Harbor Laboratory)
  • Journal of Hepatology
  • Clinical Cancer Research

Their work broadly intersects with subfields including oncology, molecular biology, cancer research, pulmonary and respiratory medicine, and epidemiology, reflecting a multidisciplinary approach to understanding cancer biology and treatment resistance.

Best Publications

  • Hypoxia promotes invasive growth by transcriptional activation of the met protooncogene.

    Selma Pennacchietti;Paolo Michieli;Maria Galluzzo;Massimiliano Mazzone

  • A multifunctional docking site mediates signaling and transformation by the hepatocyte growth factor/scatter factor receptor family

    Carola Ponzetto;Alberto Bardelli;Alberto Bardelli;Zhu Zhen;Flavio Maina

  • Drug development of MET inhibitors : targeting oncogene addiction and expedience

    Paolo M. Comoglio;Silvia Giordano;Livio Trusolino

  • Overexpression and amplification of the Met/HGF receptor gene during the progression of colorectal cancer

    M F Di Renzo;M Olivero;A Giacomini;H Porte

  • Amplification of the MET Receptor Drives Resistance to Anti-EGFR Therapies in Colorectal Cancer

    Alberto Bardelli;Simona Corso;Andrea Bertotti;Sebastijan Hobor

  • Expression of the Met/HGF receptor in normal and neoplastic human tissues.

    M. F. Di Renzo;R. P. Narsimhan;M. Olivero;S. Bretti

  • The Dual Roles of NRF2 in Cancer

    Silvia Menegon;Amedeo Columbano;Silvia Giordano

  • Tyrosine kinase receptor indistinguishable from the c-met protein.

    S. Giordano;C. Ponzetto;M. F. Di Renzo;C. S. Cooper

  • From single- to multi- target drugs in cancer therapy: when aspecificity becomes an advantage

    Annalisa Petrelli;Silvia Giordano

  • The endophilin–CIN85–Cbl complex mediates ligand-dependent downregulation of c-Met

    Annalisa Petrelli;Giorgio F. Gilestro;Stefania Lanzardo;Paolo M. Comoglio

  • The Semaphorin 4D receptor controls invasive growth by coupling with Met

    Silvia Giordano;Simona Corso;Paolo Conrotto;Stefania Artigiani

  • Negative receptor signalling

    Ivan Dikic;Silvia Giordano

  • Somatic mutations of the MET oncogene are selected during metastatic spread of human HNSC carcinomas

    M F Di Renzo;M Olivero;T Martone;A Maffe

  • Cell motility is controlled by SF2/ASF through alternative splicing of the Ron protooncogene

    Claudia Ghigna;Silvia Giordano;Haihong Shen;Federica Benvenuto

  • MicroRNAs: New tools for diagnosis, prognosis, and therapy in hepatocellular carcinoma?†

    Silvia Giordano;Amedeo Columbano

  • Tumor angiogenesis and progression are enhanced by Sema4D produced by tumor-associated macrophages.

    Jose Rafael Sierra;Simona Corso;Luisa Caione;Virna Cepero

  • Cancer therapy: can the challenge be MET?

    Simona Corso;Paolo M. Comoglio;Silvia Giordano

  • Sema4D induces angiogenesis through Met recruitment by Plexin B1.

    Paolo Conrotto;Donatella Valdembri;Simona Corso;Guido Serini

  • Biosynthesis of the protein encoded by the c-met proto-oncogene.

    Giordano S;Di Renzo Mf;Narsimhan Rp;Cooper Cs

  • Molecular mechanisms of acquired resistance to tyrosine kinase targeted therapy

    J. Rafael Sierra;J. Rafael Sierra;Virna Cepero;Virna Cepero;Silvia Giordano

Frequent Co-Authors

Paolo M. Comoglio
Paolo M. Comoglio FIRC Institute of Molecular Oncology
Amedeo Columbano
Amedeo Columbano University of Cagliari
Luca Tamagnone
Luca Tamagnone Catholic University of the Sacred Heart
Enzo Medico
Enzo Medico University of Turin
Anna Sapino
Anna Sapino University of Turin
Alberto Bardelli
Alberto Bardelli University of Turin
Luigi Naldini
Luigi Naldini Vita-Salute San Raffaele University
Massimo Aglietta
Massimo Aglietta University of Turin
Paola Chiarugi
Paola Chiarugi University of Florence
Maria M. Mota
Maria M. Mota University of Lisbon

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