World's Best Scientists 2026 revealed!
George F. Vande Woude

George F. Vande Woude

D-Index & Metrics

Biology and Biochemistry

D-Index
98
Citations
42486
World Ranking
1637
National Ranking
916

Overview

What is he best known for?

The fields of study he is best known for:

  • Gene
  • Cancer
  • Genetics

George F. Vande Woude mainly investigates Cancer research, Hepatocyte growth factor, Molecular biology, Tyrosine kinase and Receptor tyrosine kinase. His biological study spans a wide range of topics, including Carcinogenesis, Cancer, Metastasis, Signal transduction and C-Met. His Cancer study incorporates themes from c-Met inhibitor and Endocrinology.

George F. Vande Woude focuses mostly in the field of Signal transduction, narrowing it down to matters related to Receptor and, in some cases, In vivo. His work carried out in the field of Hepatocyte growth factor brings together such families of science as Cell, Thrombospondin 1, STAT protein and Cell biology. His Molecular biology study combines topics in areas such as Meiosis, RNA, Xenopus, Proto-Oncogene Proteins c-met and Kinase.

His most cited work include:

  • Met, metastasis, motility and more (2154 citations)
  • Targeting MET in cancer: rationale and progress (1002 citations)
  • Proteolytic Inactivation of MAP-Kinase-Kinase by Anthrax Lethal Factor (912 citations)

What are the main themes of his work throughout his whole career to date?

George F. Vande Woude spends much of his time researching Cancer research, Hepatocyte growth factor, Molecular biology, Cancer and Receptor tyrosine kinase. His studies deal with areas such as Paracrine signalling, Tyrosine kinase, Signal transduction, Immunology and Metastasis as well as Cancer research. The various areas that George F. Vande Woude examines in his Hepatocyte growth factor study include Autocrine signalling, Cell growth and Cell biology.

George F. Vande Woude interconnects Cell culture, Genetics, RNA, Xenopus and Proto-Oncogene Proteins c-met in the investigation of issues within Molecular biology. His Cancer study combines topics from a wide range of disciplines, such as Lung cancer and Oncology. His work deals with themes such as Carcinogenesis and Monoclonal antibody, which intersect with Receptor tyrosine kinase.

He most often published in these fields:

  • Cancer research (43.68%)
  • Hepatocyte growth factor (29.89%)
  • Molecular biology (24.14%)

What were the highlights of his more recent work (between 2012-2019)?

  • Cancer research (43.68%)
  • Hepatocyte growth factor (29.89%)
  • Receptor tyrosine kinase (20.11%)

In recent papers he was focusing on the following fields of study:

The scientist’s investigation covers issues in Cancer research, Hepatocyte growth factor, Receptor tyrosine kinase, Cancer and Signal transduction. His Cancer research research is multidisciplinary, incorporating perspectives in Tyrosine kinase, Proto-oncogene tyrosine-protein kinase Src, Breast cancer, PI3K/AKT/mTOR pathway and Monoclonal antibody. The concepts of his Hepatocyte growth factor study are interwoven with issues in Targeted therapy and Mechanism of action.

His studies in Receptor tyrosine kinase integrate themes in fields like Onartuzumab, Coiled coil, Binding site and MAPK/ERK pathway. He is studying Cancer cell, which is a component of Cancer. His study on Signal transduction also encompasses disciplines like

  • Carcinogenesis that connect with fields like Cadherin, Proto-Oncogene Proteins c-met and Immunology,
  • Phosphorylation most often made with reference to Mutation.

Between 2012 and 2019, his most popular works were:

  • Monovalent antibody design and mechanism of action of onartuzumab, a MET antagonist with anti-tumor activity as a therapeutic agent (162 citations)
  • MET: A Critical Player in Tumorigenesis and Therapeutic Target (80 citations)
  • Chromosome instability drives phenotypic switching to metastasis. (34 citations)

In his most recent research, the most cited papers focused on:

  • Gene
  • Cancer
  • Genetics

George F. Vande Woude mainly focuses on Cancer research, Receptor tyrosine kinase, Hepatocyte growth factor, Signal transduction and Tyrosine kinase. George F. Vande Woude has researched Cancer research in several fields, including Molecular biology, Targeted therapy and Hepatitis B virus. His work on ERBB3 as part of general Receptor tyrosine kinase study is frequently linked to Context, bridging the gap between disciplines.

George F. Vande Woude combines subjects such as Hepatitis B, Cancer, Bioinformatics and Hepatitis with his study of Hepatocyte growth factor. George F. Vande Woude has included themes like Cell growth, Erlotinib Hydrochloride, Erlotinib, EGFR inhibitors and Pharmacology in his Signal transduction study. The study incorporates disciplines such as Protein kinase B, Gene knockdown, Breast cancer, PI3K/AKT/mTOR pathway and MAPK/ERK pathway in addition to Tyrosine kinase.

Best Publications

  • Met, metastasis, motility and more

    Carmen Birchmeier;Walter Birchmeier;Ermanno Gherardi;George F. Vande Woude

  • Targeting MET in cancer: rationale and progress

    Ermanno Gherardi;Ermanno Gherardi;Walter Birchmeier;Carmen Birchmeier;George Vande Woude

  • Proteolytic Inactivation of MAP-Kinase-Kinase by Anthrax Lethal Factor

    Nicholas S. Duesbery;Craig P. Webb;Stephen H. Leppla;Valery M. Gordon

  • Molecular cloning of a new transforming gene from a chemically transformed human cell line

    Colin S. Cooper;Morag Park;Donald G. Blair;Michael A. Tainsky

  • Abnormal Centrosome Amplification in the Absence of p53

    Kenji Fukasawa;Taesaeng Choi;Ryoko Kuriyama;Shen Rulong

  • Function of c-mos proto-oncogene product in meiotic maturation in Xenopus oocytes

    Noriyuki Sagata;Marianne Oskarsson;Terry Copeland;John Brumbaugh

  • Mechanism of met oncogene activation

    Morag Park;Michael Dean;Colin S. Cooper;Martin Schmidt

  • Novel Therapeutic Inhibitors of the c-Met Signaling Pathway in Cancer

    Joseph Paul Eder;George F. Vande Woude;Scott A. Boerner;Patricia M. LoRusso

  • Met receptor tyrosine kinase: enhanced signaling through adapter proteins

    Kyle A Furge;Yu-Wen Zhang;George F Vande Woude

  • Activating mutations for the Met tyrosine kinase receptor in human cancer

    Michael Jeffers;Laura Schmidt;Noboru Nakaigawa;Craig P. Webb

  • Anti-apoptotic signaling by hepatocyte growth factor/Met via the phosphatidylinositol 3-kinase/Akt and mitogen-activated protein kinase pathways

    Guang-Hui Xiao;Michael Jeffers;Alfonso Bellacosa;Yasuhiro Mitsuuchi

  • Hepatocyte growth factor/scatter factor mediates angiogenesis through positive VEGF and negative thrombospondin 1 regulation

    Yu Wen Zhang;Yanli Su;Olga V. Volpert;George F. Vande Woude

  • A novel germ line juxtamembrane Met mutation in human gastric cancer.

    Jae-Ho Lee;San-Uk Han;Hyeseong Cho;Barbara Jennings

  • Inactivation of Lrg-47 and Irg-47 Reveals a Family of Interferon γ–Inducible Genes with Essential, Pathogen-Specific Roles in Resistance to Infection

    Carmen M. Collazo;George S. Yap;Gregory D. Sempowski;Kimberly C. Lusby;Kimberly C. Lusby

  • Properties of a normal mouse cell DNA sequence (sarc) homologous to the src sequence of Moloney sarcoma virus.

    Marianne Oskarsson;William L. McClements;Donald G. Blair;J. V. Maizel

  • HGF/SF‐met signaling in the control of branching morphogenesis and invasion

    Yu-Wen Zhang;George F. Vande Woude

  • The human met oncogene is related to the tyrosine kinase oncogenes

    Michael Dean;Morag Park;Michelle M. Le Beau;Terry S. Robins

  • Specific proteolysis of the c-mos proto-oncogene product by calpain on fertilization of Xenopus eggs

    Nobumoto Watanabe;George F. Vande Woude;Yoji Ikawa;Noriyuki Sagata

  • Cytoplasmic control of nuclear behavior during meiotic maturation of frog oocytes

    Nicholas S. Vande Duesbery;George F. Vande Woude

  • Erratum: Targeting MET in cancer: rationale and progress

    Ermanno Gherardi;Walter Birchmeier;Carmen Birchmeier;George Vande Woude

Frequent Co-Authors

James H. Resau
James H. Resau Van Andel Institute
Beatrice S. Knudsen
Beatrice S. Knudsen University of Utah
Gregory A. Taylor
Gregory A. Taylor Duke University
Ermanno Gherardi
Ermanno Gherardi University of Pavia
Michael Dean
Michael Dean National Institutes of Health
H. Eric Xu
H. Eric Xu Chinese Academy of Sciences
Morag Park
Morag Park McGill University
Stephen H. Leppla
Stephen H. Leppla National Institutes of Health
Carmen Birchmeier
Carmen Birchmeier Max Delbrück Center for Molecular Medicine
Michael E. Berens
Michael E. Berens Translational Genomics Research Institute

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