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D-Index & Metrics

Biology and Biochemistry

D-Index
98
Citations
33812
World Ranking
1668
National Ranking
930

Research.com Recognitions

  • 1993 - Fellow of the American Academy of Arts and Sciences
  • 1991 - Member of the National Academy of Sciences

Overview

R. John Collier is affiliated with Harvard University in the United States. Their research spans multiple fields including Biochemistry, Genetics and Molecular Biology, Immunology and Microbiology, and Medicine, with a specific focus on Molecular Biology, Immunology, Physiology, Microbiology, and Radiology, Nuclear Medicine and Imaging.

The scientist has contributed to several topics in the biomedical domain, including:

  • Ion channel regulation and function
  • Bacillus and Francisella bacterial research
  • Immunotherapy and Immune Responses
  • Pain Mechanisms and Treatments
  • Antimicrobial Peptides and Activities
  • T-cell and B-cell Immunology
  • Nicotinic Acetylcholine Receptors Study

Collier's recent publications cover areas related to bacterial toxins, immune tolerance, and pain signaling. Notable papers include:

  • "Anthrax toxins regulate pain signaling and can deliver molecular cargoes into ANTXR2+ DRG sensory neurons," 2021, Nature Neuroscience
  • "An in vivo selection-derived d-peptide for engineering erythrocyte-binding antigens that promote immune tolerance," 2021, Proceedings of the National Academy of Sciences
  • "Anthrax Toxin as a Molecular Platform to Target Nociceptive Neurons and Modulate Pain," 2020, bioRxiv (Cold Spring Harbor Laboratory)
  • "Erythrocyte-targeted immunomodulatory antigens enabled by in vivo selection of D-peptides," 2020, bioRxiv (Cold Spring Harbor Laboratory)

These publications have appeared in venues including bioRxiv (Cold Spring Harbor Laboratory), Nature Neuroscience, and the Proceedings of the National Academy of Sciences, with bioRxiv hosting multiple preprints by Collier.

Frequent collaborators of Collier are Bradley L. Pentelute, Nicole Yang, Jörg Isensee, Dylan V. Neel, and Sai Liu. The scientist has engaged closely with these co-authors in work related to immunology, molecular biology, and bacterial mechanisms.

Professional recognition includes election as a Member of the National Academy of Sciences in 1991 and a Fellow of the American Academy of Arts and Sciences in 1993.

Best Publications

  • Identification of the cellular receptor for anthrax toxin.

    K A Bradley;J Mogridge;J Mogridge;M Mourez;R J Collier

  • Crystal structure of the anthrax toxin protective antigen.

    C Petosa;R.J Collier;K.R Klimpel;S.H Leppla

  • The crystal structure of diphtheria toxin

    Seunghyon Choe;Melanie J. Bennett;Gary Fujii;Paul M. G. Curmi

  • Anthrax toxin: receptor binding, internalization, pore formation, and translocation.

    John A. T. Young;R. John Collier

  • Diphtheria toxin: mode of action and structure.

    R J Collier

  • Structure of exotoxin A of Pseudomonas aeruginosa at 3.0-Angstrom resolution.

    V S Allured;R J Collier;S F Carroll;D B McKay

  • Crystal structure of the zeta isoform of the 14-3-3 protein.

    Dong Liu;J. Bienkowska;C. Petosa;R. J. Collier

  • Anthrax protective antigen forms oligomers during intoxication of mammalian cells.

    J C Milne;D Furlong;P C Hanna;J S Wall

  • Crystal structure of the anthrax lethal factor

    AD Pannifer;TY Wong;Robert Schwarzenbacher;M Renatus

  • Structure and Activity of Diphtheria Toxin I. THIOL-DEPENDENT DISSOCIATION OF A FRACTION OF TOXIN INTO ENZYMICALLY ACTIVE AND INACTIVE FRAGMENTS

    R. J. Collier;Judith Kandel

  • On the role of macrophages in anthrax.

    P C Hanna;D Acosta;D Acosta;R J Collier

  • Understanding the mode of action of diphtheria toxin: a perspective on progress during the 20th century

    R.J Collier

  • Nucleotide sequence of the structural gene for diphtheria toxin carried by corynebacteriophage beta.

    L Greenfield;M J Bjorn;G Horn;D Fong

  • Designing a polyvalent inhibitor of anthrax toxin

    Michael Mourez;Ravi S. Kane;Jeremy Mogridge;Steve Metallo

  • Anthrax toxin: channel-forming activity of protective antigen in planar phospholipid bilayers

    R. O. Blaustein;Theresa M Koehler;R. J. Collier;A. Finkelstein

  • Antibody-directed cytotoxic agents: use of monoclonal antibody to direct the action of toxin A chains to colorectal carcinoma cells

    D G Gilliland;Z Steplewski;R J Collier;K F Mitchell

  • Anthrax protective antigen: prepore-to-pore conversion.

    Miller Cj;Elliott Jl;Collier Rj

  • The eukaryotic host factor that activates exoenzyme S of Pseudomonas aeruginosa is a member of the 14-3-3 protein family.

    Haian Fu;J. Coburn;R. J. Collier

  • pH-dependent perforation of macrophage phagosomes by listeriolysin O from Listeria monocytogenes.

    Kathryn E. Beauregard;Kyung Dall Lee;R. John Collier;Joel A. Swanson

  • Interaction of the protein kinase Raf-1 with 14-3-3 proteins

    Haian Fu;Kai Xia;D. C. Pallas;Can Cui

Frequent Co-Authors

John J. Mekalanos
John J. Mekalanos Harvard Medical School
Michael N. Starnbach
Michael N. Starnbach Harvard University
David Eisenberg
David Eisenberg Harvard University
Isaac M. Chiu
Isaac M. Chiu Harvard University
Wayne I. Lencer
Wayne I. Lencer Harvard University
Marianne Manchester
Marianne Manchester University of Montana
Brenda A. Wilson
Brenda A. Wilson University of Illinois at Urbana-Champaign
Arturo Casadevall
Arturo Casadevall Johns Hopkins University
Klaus Aktories
Klaus Aktories University of Freiburg

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