Isaac M. Chiu

Best Publications

• Nociceptor Sensory Neuron-Immune Interactions in Pain and Inflammation.

  Felipe A. Pinho-Ribeiro;Waldiceu A. Verri;Isaac M. Chiu

  988
  Citations

• Bacteria activate sensory neurons that modulate pain and inflammation

  Isaac M. Chiu;Balthasar A. Heesters;Balthasar A. Heesters;Nader Ghasemlou;Christian A. Von Hehn

  929
  Citations

• Neurogenic inflammation and the peripheral nervous system in host defense and immunopathology

  Isaac M Chiu;Isaac M Chiu;Christian A von Hehn;Christian A von Hehn;Clifford J Woolf;Clifford J Woolf

  729
  Citations

• A Neurodegeneration-Specific Gene-Expression Signature of Acutely Isolated Microglia from an Amyotrophic Lateral Sclerosis Mouse Model

  Isaac M. Chiu;Emiko T.A. Morimoto;Hani Goodarzi;Jennifer T. Liao

  727
  Citations

• The neuropeptide NMU amplifies ILC2-driven allergic lung inflammation

  Antonia Wallrapp;Samantha J. Riesenfeld;Patrick R. Burkett;Raja-Elie E. Abdulnour

  634
  Citations

• The human natural killer cell immune synapse

  Daniel M. Davis;Isaac Chiu;Marlys Fassett;George B. Cohen

  505
  Citations

• Pain and immunity: implications for host defence

  Pankaj Baral;Swalpa Udit;Isaac M. Chiu

  454
  Citations

• Silencing Nociceptor Neurons Reduces Allergic Airway Inflammation

  Sebastien Talbot;Sebastien Talbot;Raja-Elie E Abdulnour;Patrick Ryland Burkett;Seungkyu Lee;Seungkyu Lee

  426
  Citations

• T lymphocytes potentiate endogenous neuroprotective inflammation in a mouse model of ALS.

  Isaac M. Chiu;Adam Chen;Yi Zheng;Bela Kosaras

  425
  Citations

• Blocking Neuronal Signaling to Immune Cells Treats Streptococcal Invasive Infection

  Felipe A. Pinho-Ribeiro;Buket Baddal;Rianne Haarsma;Maghnus O’Seaghdha

  421
  Citations

• Nociceptor sensory neurons suppress neutrophil and γδ T cell responses in bacterial lung infections and lethal pneumonia

  Pankaj Baral;Benjamin D Umans;Lu Li;Antonia Wallrapp

  403
  Citations

• Gut-Innervating Nociceptor Neurons Regulate Peyer’s Patch Microfold Cells and SFB Levels to Mediate Salmonella Host Defense

  Nicole Y. Lai;Melissa A. Musser;Melissa A. Musser;Felipe A. Pinho-Ribeiro;Pankaj Baral

  317
  Citations

• Toll-like receptor 8 functions as a negative regulator of neurite outgrowth and inducer of neuronal apoptosis

  Yinghua Ma;Jianxue Li;Isaac Chiu;Yawen Wang

  311
  Citations

• Gut-licensed IFNγ+ NK cells drive LAMP1+TRAIL+ anti-inflammatory astrocytes

  Liliana M. Sanmarco;Michael A. Wheeler;Michael A. Wheeler;Cristina Gutiérrez-Vázquez;Carolina Manganeli Polonio

  298
  Citations

• Hyperactivation of sympathetic nerves drives depletion of melanocyte stem cells

  Bing Zhang;Sai Ma;Sai Ma;Sai Ma;Inbal Rachmin;Megan He

  272
  Citations

• Identification of a specific self-reactive IgM antibody that initiates intestinal ischemia/reperfusion injury

  Ming Zhang;William G. Austen;Isaac Chiu;Elisabeth M. Alicot

  263
  Citations

• Identification of the target self-antigens in reperfusion injury

  Ming Zhang;Elisabeth M. Alicot;Isaac Chiu;Jinan Li

  262
  Citations

• The intestinal neuro-immune axis: crosstalk between neurons, immune cells, and microbes.

  Amanda Jacobson;Daping Yang;Madeleine Vella;Isaac M. Chiu

  259
  Citations

• Substance P Release by Sensory Neurons Triggers Dendritic Cell Migration and Initiates the Type-2 Immune Response to Allergens

  Caroline Perner;Cameron H. Flayer;Xueping Zhu;Pamela A. Aderhold

  245
  Citations

• Neuro-immune Interactions in the Tissues

  Coco Chu;David Artis;Isaac M. Chiu

  244
  Citations