2026 Sangeeta S. Chavan: Immunology Researcher – H-Index, Publications & Awards

Discipline name	D-Index	World Ranking	Current World Ranking	National Ranking	Current National Ranking	Publications	Citations
Immunology	57	3588	3308	1661	1520	188	15598

Overview

Sangeeta S. Chavan is affiliated with the Feinstein Institute for Medical Research in the United States. Their research primarily focuses on the intersection of neuroscience and medicine, with a particular emphasis on vagus nerve stimulation and related neurophysiological mechanisms.

The main fields of study represented in their work include Neuroscience and Medicine, with substantial contributions to several subfields:

Neurology
Molecular Biology
Cardiology and Cardiovascular Medicine
Physiology
Sensory Systems

The topics covered extensively in their research portfolio span various areas relevant to neurostimulation and autonomic control:

Vagus Nerve Stimulation Research
Nicotinic Acetylcholine Receptors Study
Heart Rate Variability and Autonomic Control
Neuroscience of respiration and sleep
Ion Channels and Receptors
Neuropeptides and Animal Physiology
Neuroinflammation and Neurodegeneration Mechanisms

Sangeeta S. Chavan has co-authored multiple publications with several frequent collaborators, highlighting a networked research approach. Frequent co-authors include:

Kevin J. Tracey
Téa Tsaava
Eric H. Chang
Aisling Tynan
Michael Brines

The scientist's research output has appeared in a variety of journals, demonstrating a cross-disciplinary engagement with both specialized and broader biomedical audiences. Frequent publication venues include:

The FASEB Journal
Bioelectronic Medicine
Molecular Medicine
The Journal of Immunology
bioRxiv (Cold Spring Harbor Laboratory)

Selected recent papers highlight key themes in their research:

Transcutaneous auricular vagus nerve stimulation reduces pain and fatigue in patients with systemic lupus erythematosus: a randomised, double-blind, sham-controlled pilot trial (2020), Annals of the Rheumatic Diseases
Involvement of Neural Transient Receptor Potential Channels in Peripheral Inflammation (2020), Frontiers in Immunology
Identification of a brainstem locus that inhibits tumor necrosis factor (2020), Proceedings of the National Academy of Sciences
HMGB1 released from nociceptors mediates inflammation (2021), Proceedings of the National Academy of Sciences
Stimulation of the hepatoportal nerve plexus with focused ultrasound restores glucose homoeostasis in diabetic mice, rats and swine (2022), Nature Biomedical Engineering

Best Publications

Acetylcholine-synthesizing T cells relay neural signals in a vagus nerve circuit.

Mauricio Rosas-Ballina;Peder S. Olofsson;Mahendar Ochani;Sergio I. Valdés-Ferrer

1610
Citations
Vagus nerve stimulation inhibits cytokine production and attenuates disease severity in rheumatoid arthritis

Frieda A. Koopman;Sangeeta S. Chavan;Sanda Miljko;Simeon Grazio

1045
Citations
A critical cysteine is required for HMGB1 binding to Toll-like receptor 4 and activation of macrophage cytokine release

Huan Yang;Hulda S. Hreggvidsdottir;Karin Palmblad;Haichao Wang

947
Citations
Novel role of PKR in inflammasome activation and HMGB1 release

Ben Lu;Takahisa Nakamura;Karen Inouye;Jianhua Li

861
Citations
Splenic nerve is required for cholinergic antiinflammatory pathway control of TNF in endotoxemia

Mauricio Rosas-Ballina;Mahendar Ochani;William R. Parrish;Kanta Ochani

807
Citations
Mechanisms and Therapeutic Relevance of Neuro-immune Communication

Sangeeta S. Chavan;Valentin A. Pavlov;Kevin J. Tracey

643
Citations
Brain acetylcholinesterase activity controls systemic cytokine levels through the cholinergic anti-inflammatory pathway.

Valentin A. Pavlov;William R. Parrish;Mauricio Rosas-Ballina;Mahendar Ochani

535
Citations
Molecular and Functional Neuroscience in Immunity.

Valentin A Pavlov;Sangeeta S Chavan;Kevin J Tracey

419
Citations
Modulation of TNF release by choline requires alpha7 subunit nicotinic acetylcholine receptor-mediated signaling.

William R. Parrish;Mauricio Rosas-Ballina;Margot Gallowitsch-Puerta;Mahendar Ochani

404
Citations
JAK/STAT1 signaling promotes HMGB1 hyperacetylation and nuclear translocation

Ben Lu;Daniel J. Antoine;Kevin Kwan;Peter Lundbäck

403
Citations
MD-2 is required for disulfide HMGB1-dependent TLR4 signaling

Huan Yang;Haichao Wang;Zhongliang Ju;Ahmed A. Ragab

389
Citations
High Mobility Group Box Protein 1 (HMGB1): The Prototypical Endogenous Danger Molecule.

Huan Yang;Haichao Wang;Sangeeta S Chavan;Ulf Andersson

361
Citations
Transcutaneous vagus nerve stimulation reduces serum high mobility group box 1 levels and improves survival in murine sepsis

Jared M. Huston;Margot Gallowitsch-Puerta;Mahendar Ochani;Kanta Ochani

358
Citations
The Selective α7 Agonist GTS-21 Attenuates Cytokine Production in Human Whole Blood and Human Monocytes Activated by Ligands for TLR2, TLR3, TLR4, TLR9, and RAGE

Mauricio Rosas-Ballina;Richard S. Goldstein;Margot Gallowitsch-Puerta;Lihong Yang

244
Citations
Cholinergic anti-inflammatory pathway activity and High Mobility Group Box-1 (HMGB1) serum levels in patients with rheumatoid arthritis.

Richard S Goldstein;Annette Bruchfeld;Annette Bruchfeld;Lihong Yang;Abdul R Qureshi

226
Citations
HMGB1 mediates cognitive impairment in sepsis survivors.

Sangeeta S Chavan;Patricio T Huerta;Sergio Robbiati;SI Valdes-Ferrer

224
Citations
α7 Nicotinic Acetylcholine Receptor Signaling Inhibits Inflammasome Activation by Preventing Mitochondrial DNA Release

Ben Lu;Kevin Kwan;Yaakov A. Levine;Peder S. Olofsson

215
Citations
Identification of cytokine-specific sensory neural signals by decoding murine vagus nerve activity.

Theodoros P Zanos;Harold A Silverman;Todd Levy;Tea Tsaava

202
Citations
Post-sepsis syndrome - an evolving entity that afflicts survivors of sepsis.

Zachary Mostel;Zachary Mostel;Abraham Perl;Abraham Perl;Matthew Marck;Syed F. Mehdi

192
Citations
α7 Nicotinic Acetylcholine Receptor (α7nAChR) Expression in Bone Marrow–Derived Non–T Cells Is Required for the Inflammatory Reflex

Peder S Olofsson;David A Katz;Mauricio Rosas-Ballina;Yaakov A Levine

174
Citations
Essential Neuroscience in Immunology.

Sangeeta S Chavan;Kevin J Tracey

148
Citations
Whole blood cytokine attenuation by cholinergic agonists ex vivo and relationship to vagus nerve activity in rheumatoid arthritis.

A. Bruchfeld;R. S. Goldstein;S. Chavan;N. B. Patel

132
Citations

Frequent Co-Authors

Kevin J. Tracey Feinstein Institute for Medical Research

Valentin A. Pavlov Feinstein Institute for Medical Research

Huan Yang Feinstein Institute for Medical Research

Jianhua Li Feinstein Institute for Medical Research

Ulf Andersson Karolinska University Hospital

Haichao Wang Feinstein Institute for Medical Research

Betty Diamond Feinstein Institute for Medical Research

Christine N. Metz Feinstein Institute for Medical Research

Tak W. Mak Princess Margaret Cancer Centre

Ping Wang Feinstein Institute for Medical Research

External Links

Personal website of Sangeeta S. Chavan

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